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Talha B. Emran
Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, Bangladesh
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Elevated serum malondialdehyde (MDA), insulin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH), and reduced antioxidant vitamins in polycystic ovarian syndrome patients Abdullah A. Mahmud; Umme H. Anu; Kazi A. Foysal; Mahedi Hasan; Sazaul M. Sazib; Abdullah A. Ragib; Asad B. Taher; Md Shajjad Hossain; Mohammad S. Islam; Md Shohel Hossain; Talha B. Emran
Narra J Vol. 2 No. 1 (2022): April 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i1.56

Abstract

Elevated oxidative stress and hormonal imbalance have been suggested associate with polycystic ovarian syndromes (PCOS), a causal factor for unsuccessful pregnancy outcomes and other associated complications in women. The aim of this study was to compare the oxidative stress markers and different relevant hormone between pregnant women with and without PCOS. The levels of malondialdehyde (MDA), insulin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH), vitamin A and vitamin C were measured in 80 pregnant women with PCOS and 80 healthy pregnancies. The mean MDA and insulin levels were significantly elevated in pregnant with PCOS compared to healthy controls (1.98±0.07 vs. 1.06±0.02 nmol/mL and 11.15±0.25 vs. 6.67±0.25 mIU/L, respectively with p<0.001 for both). Compared to healthy controls, the mean concentrations of FSH (3.65±0.16 vs. 1.75±0.10 IU/L) and LH (15.67±0.63 vs. 3.65±0.16 IU/L) were significantly higher in pregnant women with PCOS, p<0.001 for both comparisons. Similarly, the concentration of serum TSH was also higher in PCOS cases compared to controls (2.79±0.22 vs.2.34±0.06, p=0.048). In contrast, the levels of vitamin A and C were lower in PCOS cases compared to healthy pregnancy group, 0.45±0.01 vs. 1.05±0.01 and 0.26±0.01 vs. 0.53±0.02, respectively with p-values <0.001 for both comparations. In conclusion, in PCOS, serum MDA, insulin, FSH, LH and TSH levels elevated while the level of antioxidant vitamins lower compared to healthy pregnant women. Unusual hormonal imbalance and increase of oxidative stress markers during the pregnancy might important to establish the PCOS diagnosis.
Willingness-to-pay for COVID-19 vaccine in ten low-middle-income countries in Asia, Africa and South America: A cross-sectional study Malik Sallam; Samsul Anwar; Amanda Yufika; Marhami Fahriani; Milda Husnah; Hendrix I. Kusuma; Rawan Raad; Namareg ME. Khiri; Rashed YA. Abdalla; Rashed Y. Adam; Mohajer IH. Ismaeil; Asma Y. Ismail; Wajdi Kacem; Zeineb Teyeb; Khaoula Aloui; Montacer Hafsi; Nesrine Ben Hadj Dahman; Manel Ferjani; Dalia Deeb; Dina Emad; Farah S. Sami; Kirellos Said Abbas; Fatma A. Monib; Subramaniam R; Suhrud Panchawagh; Khan Sharun; Sunil Anandu; Mahir Gachabayov; Md A. Haque; Talha B. Emran; Guilherme W. Wendt; Lirane ED. Ferreto; María F. Castillo-Briones; Rocío B. Inostroza-Morales; Sebastián A. Lazcano-Díaz; José T. Ordóñez-Aburto; Jorge E. Troncoso-Rojas; Emmanuel O. Balogun; Akele R. Yomi; Abiodun Durosinmi; Esther N. Adejumo; Eyiuche D. Ezigbo; Morteza Arab-Zozani; Elham Babadi; Edris Kakemam; Irfan Ullah; Najma I. Malik; Deema Dababseh; Francesco Rosiello; Seyi S. Enitan
Narra J Vol. 2 No. 1 (2022): April 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i1.74

Abstract

Vaccine hesitancy is considered as one of the greatest challenges to control the ongoing coronavirus disease 2019 (COVID-19) pandemic. A related challenge is the unwillingness of the general public to pay for vaccination. The objective of this study was to determine willingness-to-pay (WTP) for COVID-19 vaccine among individuals from ten low-middle-income countries (LMICs) in Asia, Africa, and South America. Data were collected using an online questionnaire distributed during February - May 2021 in ten LMICs (Bangladesh, Brazil, Chile, Egypt, India, Iran, Nigeria, Pakistan, Sudan, and Tunisia). The major response variable of in this study was WTP for a COVID-19 vaccine. The assessment of COVID-19 vaccine hesitancy was based on items adopted from the World Health Organization (WHO) Strategic Advisory Group of Experts (SAGE) vaccine hesitancy scale constructs. In this study, 1337 respondents included in the final analysis where the highest number of respondents was from India, while the lowest number was from Egypt. A total of 88.9% (1188/1337) respondents were willing to pay for the COVID-19 vaccination, and 11.1% (149/1337) were not. The average WTP for COVID-19 vaccination was 87.9 US dollars ($), (range: $5-$200). The multivariate model analysis showed that the country, monthly household income, having a history of respiratory disease, the agreement that routine vaccines recommended by health workers are beneficial and having received the flu vaccination within the previous 12 months were strongly associated with the WTP. Based on the country of origin, the highest mean WTP for COVID-19 vaccine was reported in Chile, while the lowest mean WTP for the vaccine was seen among the respondents from Sudan. The availability of free COVID-19 vaccination services appears as a top priority in the LMICs for successful control of the ongoing pandemic. This is particularly important for individuals of a lower socio-economic status. The effects of complacency regarding COVID-19 extends beyond vaccine hesitancy to involve less willingness to pay for COVID-19 vaccine and a lower value of WTP for the vaccine.
Hepatitis E virus in pigs and the environment: An updated review of public health concerns Tauseef Ahmad; Hui Jin; Kuldeep Dhama; Mohd. Iqbal Yatoo; Ruchi Tiwari; Muhammad Bilal; Manish Dhawan; Talha B. Emran; Jeehan H. Alestad; Hatem M. Alhani; Habib K. BinKhalaf; Ali A. Rabaan
Narra J Vol. 2 No. 2 (2022): August 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i2.78

Abstract

Hepatitis E virus (HEV) is an important public health problem and is responsible for both acute and chronic viral hepatitis. Public health implications of HEV are derived from its transmission route, either water-borne or food-borne, and its zoonotic potential. Not only in developing countries, but HEV cases are also found in a high number in developed countries. The spread of HEV to the environment might pollute surface waters, which could act as the source of infection for both humans and animals. Identification of the virus in animal products suggests the circulation of HEV within water and food chains. High seroprevalence and circulation of HEV in livestock, in particular pigs, as well as in environmental samples warrants further investigation into pig markets. HEV virulence in different environments and meat supply chains could shed light on the possible sources of infection in humans and the degree of occupational risk. The purpose of this review is to discuss HEV infections with an emphasis on livestock- and environment-related risk factors, and food-borne, water-borne, and zoonotic transmissions.
Co-Authors Abdullah A. Mahmud Abdullah A. Ragib Abiodun Durosinmi Akele R. Yomi Ali A. Rabaan Amanda Yufika Asad B. Taher Asma Y. Ismail Dalia Deeb Deema Dababseh Dina Emad Edris Kakemam Elham Babadi Emmanuel O. Balogun Esther N. Adejumo Eyiuche D. Ezigbo Farah S. Sami Fatma A. Monib Francesco Rosiello Guilherme W. Wendt Habib K. BinKhalaf Hatem M. Alhani Hendrix I. Kusuma Hui Jin Irfan Ullah Jeehan H. Alestad Jorge E. Troncoso-Rojas José T. Ordóñez-Aburto Kazi A. Foysal Khan Sharun Khaoula Aloui Kirellos Said Abbas Kuldeep Dhama Lirane ED. Ferreto Mahedi Hasan Mahir Gachabayov Malik Sallam Manel Ferjani Manish Dhawan Marhami Fahriani María F. Castillo-Briones Md A. Haque Md Shajjad Hossain Md Shohel Hossain Milda Husnah Mohajer IH. Ismaeil Mohammad S. Islam Mohd. Iqbal Yatoo Montacer Hafsi Morteza Arab-Zozani Muhammad Bilal Najma I. Malik Namareg ME. Khiri Nesrine Ben Hadj Dahman Rashed Y. Adam Rashed YA. Abdalla Rawan Raad Rocío B. Inostroza-Morales Ruchi Tiwari Samsul Anwar Sazaul M. Sazib Sebastián A. Lazcano-Díaz Seyi S. Enitan Subramaniam R Suhrud Panchawagh Sunil Anandu Tauseef Ahmad Umme H. Anu Wajdi Kacem Zeineb Teyeb