Rahman, Ardizal
Department Of Ophthalmology, Faculty Of Medicine, Universitas Andalas, Padang, Indonesia

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Rhabdomyosarcoma Orbita Elfi Risalma Puteri; Ardizal Rahman
Jurnal Kesehatan Andalas Vol 8, No 3 (2019): Online September 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i3.1064

Abstract

Rhabdomyosarcoma (RMS) merupakan tumor ganas pada jaringan lunak yang sering mengenai anak-anak. Lokasi primernya 25-30% pada orbita. Tumor ini merupakan tumor yang agresif, dengan kecenderung terjadi invasif lokal dan dapat terjadi rekurensi lokal, dengan metastasis secara hematogen dan limfatik. Dilaporkan kasus Rhabdomyosarcoma orbita pada anak laki-laki umur 12 tahun dengan progresivitas yang cepat , dengan hasil pemeriksaan patologi anatomi menunjukkan suatu embryonal rhabdomyosarcoma retroorbita serta penatalaksanaannya. Saat ini penatalaksanaan RMS orbita tidak hanya dengan penatalaksanaan bedah saja, dengan perkembangan radioterapi dan khemoterapi dapat meningkatkan survival rate penderita RMS. Selain itu dibutuhkan kolaborasi antara Konsultan Onkologi Mata dengan Bedah Saraf serta Konsultan Pediatrik Onkologi.
Metastasis Tumor ke Orbita Ardizal Rahman; Rozy Oneta
Jurnal Kesehatan Andalas Vol 7 (2018): Supplement 1
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v7i0.763

Abstract

AbstrakMetastasis ke orbita adalah entitas klinis yang langka, terjadi 2%-3% pasien dengan keganasan. Pada orang dewasa, tumor payudara dan paru-paru menyebabkan sebagian besar metastasis orbita, sedangkan pada anak-anak disebabkan oleh neuroblastoma dan leukemia. Tujuan: Untuk menggambarkan profil kasus karsinoma metastatise ke orbita di Sub Bagian Onkologi, Bagian Ophthalmologi, Rumah Sakit Dr. M. Djamil di Padang. Metode: Tinjauan retrospektif rekam medis pasien dengan karsinoma metastatise ke orbita mulai Januari 2003 - Desember 2015. Meliputi data umum, data tumor, temuan klinis, metode diagnostik dan perawatan dianalisis. Hasil: Dari 16 pasien, 10 orang dewasa dan 6 anak. Tumor primer pada anak-anak adalah leukemia 4 (66,7%), dan limfoma ganas 2 (33,3%) pasien, sedangkan pada dewasa adalah payudara 4 (40%), tiroid 4 (40%), dan leukemia 2 (20%) pasien. Usia rata-rata saat diagnosis adalah 6,8 tahun (4 bulan sampai 10 tahun) untuk anak-anak, dan 42,7 tahun (34 sampai 56 tahun) untuk orang dewasa. Orbita kiri 6 (37,5%), orbit kanan 6 (37,5%), dan kedua orbita 4 (25%) kasus. Temuan klinis yang paling sering adalah proptosis 13 (81,25%) kasus. Pengobatan diberikan kepada 14 pasien, karena 2 pasien menolak pengobatan, meliputi kemoterapi 8 (50%), radiasi 2 (12,5%), kombinasi kemoterapi + bedah 2 (12,5%), dan simtomatik 2 (12,5%) pasien. Kesimpulan: Kanker primer yang paling umum bermetastasis ke orbita adalah kanker payudara dan kanker tiroid pada orang dewasa, dan leukemia pada anak-anak.
Clinical Profile of Proptosis in Dr. M. Djamil General Hospital Padang Feby Helwina; Ardizal Rahman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 6 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i6.523

Abstract

Background. Proptosis is a condition that describes a protrusion or forward shift of the eyeball and is commonly used to describe the condition of protrusion of the eyeball. Proptosis generally occurs due to a mismatch between the orbital capacity and the volume of the tissue structure in the orbital cavity. It is a common manifestation of a wide variety of diseases of the structures in and around the orbit and in some systemic diseases. This study aimed to describe the clinical profile of proptosis patients in Dr. M. Djamil General Hospital Padang. Methods. We reviewed the medical record of the oncology subdivision of ophthalmology patients associated with proptosis retrospectively, such as inflammatory, infectious, tumors, and vascular, admitted to the M.Djamil General Hospital in Padang from January 2019 to August 2020. The ocular and systemic history and examination details were recorded. Results. We found 48 proptosis patients from January 2019 to August 2020, consisting of 30(62.5%) males and 18(37,5%) females. The majority of subjects were in the Adult age group (79,17%). Unilateral and bilateral proptosis were found in 37(77%) and 11(23%), with mostly axial proptosis (83,33%). Inflammatory tumors were found in 17(35,41) and 29(60%) patients. Conclusion. Proptosis is a common clinical feature of various local and systemic diseases. Even though proptosis have diverse etiology and pathogenesis, they usually present with similar clinical manifestation. Proptosis may be one of the most important keys to disease guidance from a close structure that requires a multidisciplinary approach.
Clinical Profile of Proptosis in Dr. M. Djamil General Hospital Padang Feby Helwina; Ardizal Rahman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 6 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i6.523

Abstract

Background. Proptosis is a condition that describes a protrusion or forward shift of the eyeball and is commonly used to describe the condition of protrusion of the eyeball. Proptosis generally occurs due to a mismatch between the orbital capacity and the volume of the tissue structure in the orbital cavity. It is a common manifestation of a wide variety of diseases of the structures in and around the orbit and in some systemic diseases. This study aimed to describe the clinical profile of proptosis patients in Dr. M. Djamil General Hospital Padang. Methods. We reviewed the medical record of the oncology subdivision of ophthalmology patients associated with proptosis retrospectively, such as inflammatory, infectious, tumors, and vascular, admitted to the M.Djamil General Hospital in Padang from January 2019 to August 2020. The ocular and systemic history and examination details were recorded. Results. We found 48 proptosis patients from January 2019 to August 2020, consisting of 30(62.5%) males and 18(37,5%) females. The majority of subjects were in the Adult age group (79,17%). Unilateral and bilateral proptosis were found in 37(77%) and 11(23%), with mostly axial proptosis (83,33%). Inflammatory tumors were found in 17(35,41) and 29(60%) patients. Conclusion. Proptosis is a common clinical feature of various local and systemic diseases. Even though proptosis have diverse etiology and pathogenesis, they usually present with similar clinical manifestation. Proptosis may be one of the most important keys to disease guidance from a close structure that requires a multidisciplinary approach.
Orbital Lymphoma: Clinical Features and Management at Dr. M. Djamil General Hospital in 2018 Messia Refri Rahmi; Ardizal Rahman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 9 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i9.565

Abstract

Background: Orbital lymphoma is found in 50-60% of ocular adnexal lymphomas, with approximately 90% of orbital lymphomas being Non-Hodgkin's lymphomas. Clinical features may include proptosis, ptosis, limitation of eye movement, and salmon patch lesions on the conjunctiva. If an orbital tumor is present, an accurate histopathological examination is important in the management of orbital lymphoma. Because of nonspecific clinical signs and symptoms, some diagnostic delays may occur. The purpose of the study was to evaluate the clinical features, diagnostic approach, and treatment choice in orbital lymphomas. Methods: We identified patients diagnosed with orbital lymphoma in an outpatient clinic in Dr. M. Djamil General Hospital from January to December 2018. Patients’ medical records were reviewed retrospectively. Results: The patient group consisted of 6 patients (five males and one female) with a median age of 58 years. Proptosis and orbital swelling were the leading clinical symptoms, mainly found unilateral (five cases). The diagnosis was confirmed by a surgical biopsy. One histology result showed lymph node hyperplasia, which didn't suit the clinical manifestation and got re-reviewed. All histology results then showed non-Hodgkin’s lymphoma with the small lymphocytic type (100%). Five patients received systemic chemotherapy with the CHOP regimen protocol, and one patient refused to get further chemotherapy treatment. Conclusion: When unmatched orbital symptoms with histology results are present, re-reviewing the histology result is essential. Once the diagnosis is established, systemic chemotherapy is indicated and can proceed so there will be no delay in treatment
Orbital Lymphoma: Clinical Features and Management at Dr. M. Djamil General Hospital in 2018 Messia Refri Rahmi; Ardizal Rahman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 9 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i9.565

Abstract

Background: Orbital lymphoma is found in 50-60% of ocular adnexal lymphomas, with approximately 90% of orbital lymphomas being Non-Hodgkin's lymphomas. Clinical features may include proptosis, ptosis, limitation of eye movement, and salmon patch lesions on the conjunctiva. If an orbital tumor is present, an accurate histopathological examination is important in the management of orbital lymphoma. Because of nonspecific clinical signs and symptoms, some diagnostic delays may occur. The purpose of the study was to evaluate the clinical features, diagnostic approach, and treatment choice in orbital lymphomas. Methods: We identified patients diagnosed with orbital lymphoma in an outpatient clinic in Dr. M. Djamil General Hospital from January to December 2018. Patients’ medical records were reviewed retrospectively. Results: The patient group consisted of 6 patients (five males and one female) with a median age of 58 years. Proptosis and orbital swelling were the leading clinical symptoms, mainly found unilateral (five cases). The diagnosis was confirmed by a surgical biopsy. One histology result showed lymph node hyperplasia, which didn't suit the clinical manifestation and got re-reviewed. All histology results then showed non-Hodgkin’s lymphoma with the small lymphocytic type (100%). Five patients received systemic chemotherapy with the CHOP regimen protocol, and one patient refused to get further chemotherapy treatment. Conclusion: When unmatched orbital symptoms with histology results are present, re-reviewing the histology result is essential. Once the diagnosis is established, systemic chemotherapy is indicated and can proceed so there will be no delay in treatment
Pediatric Primary Orbital Tumors in Dr.M. Djamil General Hospital Padang Elfi Risalma; Ardizal Rahman
Majalah Oftalmologi Indonesia Vol 43 No 2 (2017): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.232 KB) | DOI: 10.35749/journal.v43i2.153

Abstract

Introduction : Primary orbital tumors of childhood are different from tumors that occur in adults. Many are congenital with early presentation. In pediatric population, a delay in diagnosis of orbital tumors , even benign tumor can lead to vision loss and deformity. Objective : To report pediatric primary orbital tumors in Dr.M.Djamil Hospital Padang. Method : A retrospective study of orbital tumors in pediatric patients admitted to DR.M.Djamil Hospital between 2003- 2016. Data were obtained from medical records which described patients characteristics based on type, sex,presentation, and management. Result : There were 36 patients of pediatric primary orbital tumors which consist of 20 boys and 16 girls, diagnosis based onclinical sympoms, CT-Scan and pathological examination. The most common tumors in pediatric was Rhabdomyosarcoma in 11 patients (30,55%), Glioma of the Optic nerve in 8 patients (22.22%), Limphoma Malignum in 5 patients (13.88%), Capillary Hemangiomas in 2 patients (5.55%), Cavernous Hemangioma in 2 patients (5.55%), AV Malformation in 2 patients (5.55%), Meningioma in 1 patient (2.77%), Neurofibromatosis in 1 patient (2.77%), Neurilemomoa in 1 patient (2.77%), Limfohemangioma in 1 patient (2.77%), osteoma in 1 patient (2.77%) and Adenoid Cystic Carcinoma in 1 patient (2,94%). Surgery had been performed in 11 patients (30.55%), chemotherapy in 7 patients (19.44%), radiotherapy in 1 patient (2,77%), Combination therapy in 2 patient (5.55%), medical therapy in 1 patient (2.77%) and the remains 14 patients (38.89%) were observed. Conclusion : There were 36 cases pediatric orbital tumors during 14 years. The most common tumor was Rhabdomyosarcoma. Management of pediatric orbital tumors consists of surgery, chemotherapy, radiotherapy and combination therapy.
Palpebral Basal Cell Carcinoma Profile at Dr. M. Djamil General Hospital Padang, Indonesia Rikha Erina; Ardizal Rahman; Mardijas Efendi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 13 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i13.652

Abstract

Background: Basal cell carcinoma (BCC) or basalioma is the world's most common type of non-melanoma skin cancer. 80% of BCC occurs in the head and neck area, and 20% occurs in the palpebrals. BCC contributes to 90-95% of malignancies that occur in the palpebrals, is more common in males, and the incidence is higher in those over 60 years of age. BCC grows slowly (slow-growing) and rarely metastasizes but can cause local destruction of surrounding structures. This study aims to explore the profile of palpebral basal cell carcinoma at Dr. M. Djamil General Hospital Padang, Indonesia. Methods: This study is a descriptive observational study. A total of 36 research subjects participated in this study. Data analysis was performed using SPSS univariately. Results: Palpebral basal cell carcinoma most often occurs in the age group of 61-70 years. Gender predilection is more common in men than women and generally occurs unilaterally. More people work outdoors than indoors. The inferior palpebral is the predilection for most tumor sites, and tumor invasion is found in the orbital area in 30.56% of cases. Wide excision and palpebral reconstruction are the most common treatment options. Conclusion: Basal cell carcinoma of the lids most often occurs in the age group of 61-70 years, gender of male, unilateral, more working outdoors, the most predilection in the inferior palpebral and tumor invasion is found in the orbital area in 30.56% of cases, The most common treatments are wide excision and palpebral reconstruction.
Comparison of Central Corneal Thickness and Lamina Cribrosa Thickness in Ethnic Indians and Ethnic Malays as Predictors of Glaucomatous Optic Neuropathy Meironi Waimir; Andrini Ariesti; Ardizal Rahman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 13 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i13.655

Abstract

Background: Glaucoma poses a public health problem because it is the second leading cause of blindness after cataracts. A thinner central corneal thickness (CCT) is also a contributor to the development of primary open-angle glaucoma (POAG). Lamina cribrosa (LC) is a structure of the optic nerve head (ONH). LC structural changes such as thinning, posterior displacement, and connective tissue deficiency are associated with the mechanism of retinal nerve fiber layer (RNFL) thickness damage, leading to glaucomatous optic neuropathy. Methods: Cross-sectional analytic observational study. A total of 36 eyes from 36 research subjects participated in this study. Data analysis was carried out using SPSS version 25. Then, univariate and bivariate analyzes were carried out to see the difference in CCT and LC thicknesses. Results: The average CCT in ethnic Indians is 514.33 ± 14,142 μm and in ethnic Malays, 542.06 ± 17,234 μm. In this study, there were differences in the average CCT in Indian ethnicity and Malay ethnicity, which was statistically meaningful with a p-value = 0.000. Conclusion: There are differences in the average central corneal thickness and lamina cribrosa thickness in ethnic Indians compared to ethnic Malays, where the central corneal thickness and lamina cribrosa thickness in ethnic Indians are thinner than ethnic Malays.
Overview of Bilateral Retinoblastoma at Dr. M. Djamil General Hospital, Padang, Indonesia Ficky Ferliando; Ardizal Rahman
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 16 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i16.699

Abstract

Background: Retinoblastoma is the most common intraocular primary malignant tumor in children. In the United States, cases of retinoblastoma are estimated to be found in 1 in 18,000 children under 5 years. The incidence of retinoblastoma ranges from 1:14.00 to 1:34.000 live births. The highest incidence occurs in developing countries. This study aimed to provide a clinical picture of bilateral retinoblastoma at Dr. M. Djamil General Hospital, Padang, Indonesia, as basic data for further policy-making in order to optimize services related to the management of bilateral retinoblastoma. Methods: This study was a descriptive observational study with 29 study subjects. Sociodemographic, clinical, and management data are presented descriptively. Data analysis was performed with the help of SPSS software version 25. Results: Based on the age group, the majority of bilateral retinoblastoma cases were less than 5 years old, with the most age range being 3-4 years. The majority of therapeutic management for cases of bilateral retinoblastoma is exenteration in combination with chemotherapy. Conclusion: A combination of surgery and chemotherapy is the most frequently used treatment for bilateral retinoblastoma at Dr. M. Djamil General Hospital, Padang, Indonesia.