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All Journal Jurnal Riset Kesehatan Nasional ad-Dawaa : Journal of Pharmaceutical Sciences Udayana Journal of Social Sciences and Humanities (UJoSSH) Jurnal Pijar MIPA JRKN Jurnal Pengabdian Kepada Masyarakat Itekes Bali
Putu Indrayoni
Institut Teknologi Dan Kesehatan Bali
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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PENGARUH EKSTRAK AVERRHOA BILIMBI L. TERHADAP JUMLAH SEL BETA PANKREAS TIKUS HIPERGLIKEMIA Indrayoni, Putu; Damayanti, Ida Ayu Manik
Jurnal Riset Kesehatan Nasional Vol 5, No 2 (2021)
Publisher : Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37294/jrkn.v5i2.344

Abstract

Latar Belakang : Diabetes mellitus merupakan sejumlah gangguan metabolisme yang ditandai dengan hiperglikemia pada kondisi tanpa penanganan. Diabetes ditandai dengan tingginya kadar glukosa plasma puasa ≥ 126 mg/dL atau kadar gula darah 2 jam setelah makan ≥ 200 mg/dL selama OGTT (oral glucose tolerance test) atau kadar A1C ≥ 6,5% atau adanya krisis hiperglikemia dengan glukosa plasma acak ≥ 200 mg/dL. Bahan makanan dan modifikasi gaya hidup yang berkaitan dengan suplai antioksidan mampu menjadi profilaksis yang efektif melawan stress oksidatif pada diabetes dan komplikasinya. Salah satu sumber antioksidan alami adalah daun Averrhoa bilimbi L. yang telah digunakan secara tradisional sebagai antidiabetes. Daun A. bilimbi L. mengandung alkaloid, tannin, saponin, flavonoid, glikosida jantung, glikosida, triterpene, fenol dan karbohidrat. Efek hipoglikemia dari A. bilimbi L. diakibatkan oleh kandungan flavonoid dan saponin.Metode : Penelitian ini menggunakan tikus hiperglikemia yang diinduksi aloksan.  Perlakuan diberikan selama 21 hari dan menggunakan glibenclamid (0,66 mg/kg BB) sebagai control positif. Pewarnaan preparate sel beta menggunakan metode Gomori Aldehyde Fuschine dan Nuclear Fast Red. Pengamatan terhadap jumlah sel beta pancreas tikus dilakukan pada hari ke 7 dan ke 21 dengan menentukan jumlah rerata sel beta yang teramati pada 3 layang pandang. Analisis statistic dilakukan menggunakan program SPSS for windows 16,0 version.Hasil : Penurunan jumlah sel beta pancreas terjadi secara bermakna pada kelompok control dibandingkan dengan kelompok perlakuan (p<0,05) yaitu sebesar 32,19%.Kesimpulan : Aktivitas antioksidan A. bilimbi L. mampu mencegah penurunan jumlah sel beta pada tikus hiperglikemia.
Health Behavior of Abuan Village Community: Social Dimension Review Asthadi Mahendra Bhandesa; Putu Indrayoni; Ni Luh Putu Kartiningsih
Udayana Journal of Social Sciences and Humanities Vol 3 No 1 (2019): UJoSSH, Feburary 2019
Publisher : Research and Community Services Institutes of Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.009 KB) | DOI: 10.24843/UJoSSH.2019.v03.i01.p04

Abstract

The development of health is basically an effort to increase awareness, willingness, and the ability of every person to commit a healthy life to achieve the highest level of public health. Health behavior is influenced by several factors including physical, mental, spiritual, and social. This study aims to gain clarity about the social dimensions of the health behavior of the people of Abuan Village, Kecut, Bangli. Data collection in this research using observation, interview, and document study technique. Furthermore, the technique of data analysis is through data reduction or chosen according to research purpose. In the process of data analysis carried out throughout the study or carried out continuously from the beginning to the end of the study. Through the process of systematically tracking and arranging interview transcripts, field notes, and other materials, showed that the social dimension of health behavior in the form of a) human relationship with God; b) human relationships with humans; and c) human relationships with the environment.
PENGARUH EKSTRAK AVERRHOA BILIMBI L. TERHADAP JUMLAH SEL BETA PANKREAS TIKUS HIPERGLIKEMIA Putu Indrayoni; Ida Ayu Manik Damayanti
Jurnal Riset Kesehatan Nasional Vol. 5 No. 2 (2021)
Publisher : Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1777.724 KB) | DOI: 10.37294/jrkn.v5i2.344

Abstract

Latar Belakang : Diabetes mellitus merupakan sejumlah gangguan metabolisme yang ditandai dengan hiperglikemia pada kondisi tanpa penanganan. Diabetes ditandai dengan tingginya kadar glukosa plasma puasa ≥ 126 mg/dL atau kadar gula darah 2 jam setelah makan ≥ 200 mg/dL selama OGTT (oral glucose tolerance test) atau kadar A1C ≥ 6,5% atau adanya krisis hiperglikemia dengan glukosa plasma acak ≥ 200 mg/dL. Bahan makanan dan modifikasi gaya hidup yang berkaitan dengan suplai antioksidan mampu menjadi profilaksis yang efektif melawan stress oksidatif pada diabetes dan komplikasinya. Salah satu sumber antioksidan alami adalah daun Averrhoa bilimbi L. yang telah digunakan secara tradisional sebagai antidiabetes. Daun A. bilimbi L. mengandung alkaloid, tannin, saponin, flavonoid, glikosida jantung, glikosida, triterpene, fenol dan karbohidrat. Efek hipoglikemia dari A. bilimbi L. diakibatkan oleh kandungan flavonoid dan saponin.Metode : Penelitian ini menggunakan tikus hiperglikemia yang diinduksi aloksan.  Perlakuan diberikan selama 21 hari dan menggunakan glibenclamid (0,66 mg/kg BB) sebagai control positif. Pewarnaan preparate sel beta menggunakan metode Gomori Aldehyde Fuschine dan Nuclear Fast Red. Pengamatan terhadap jumlah sel beta pancreas tikus dilakukan pada hari ke 7 dan ke 21 dengan menentukan jumlah rerata sel beta yang teramati pada 3 layang pandang. Analisis statistic dilakukan menggunakan program SPSS for windows 16,0 version.Hasil : Penurunan jumlah sel beta pancreas terjadi secara bermakna pada kelompok control dibandingkan dengan kelompok perlakuan (p<0,05) yaitu sebesar 32,19%.Kesimpulan : Aktivitas antioksidan A. bilimbi L. mampu mencegah penurunan jumlah sel beta pada tikus hiperglikemia.
AKTIVITAS EKSTRAK HIBISCUS ROSA-SINENSIS L. DAN BACCAUREA RACEMOSA TERHADAP PERTUMBUHAN RAMBUT PADA ALOPECIA YANG DIINDUKSI STRESS Putu Indrayoni; Anak Agung Istri Mas Padmiswari
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 5 No 1 (2022)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v5i1.27645

Abstract

Alopecia is the loss of excess hair that causes baldness, either temporarily or permanently. Physical and emotional stress are the most common causes. This study aims to determine the activity of H. rosa-sinensis L. and B. racemosa extracts on stress-induced hair growth in alopecia. Stress induction in male Wistar albino rats was obtained using the tail suspension test (TST) method. The results of the chemical content test were the total phenol content test (4,223.06 mg/100 g), total flavonoid (10,383.12 mg/100 g) and DPPH free radical reduction of B. racemosa (EB) extracts (1,593.17 mg/L GAEAC) were greater than those of the H. rosa-sinensis L. (EH) extract. The longest hair and highest hair density were obtained in the Minoxidil 2% group. While the most hair follicles were found in the group given the combination of EH and EB = 1: 1. The content of phenolic and flavonoid substances affects the hair growth activity. KEYWORDS: alopecia, stress, hibiscus, baccaurea, DPPH
Antioxidant activity test of combination of Centella asiatica leaf extract and mint leaf extract as an alternative herbal drink A.A. Istri Mas Padmiswari; Nadya Treesna Wulansari; Putu Indrayoni
Jurnal Pijar Mipa Vol. 18 No. 1 (2023): January 2023
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v18i1.4520

Abstract

Antioxidant compounds are vital for the body. An imbalance in the body's levels of free radicals and antioxidants will cause oxidative stress and cause disease because free radicals will damage the surrounding molecules (lipids, proteins, and nucleic acids), causing damage to tissues and cells. Today many studies are interested in using natural antioxidants in food, beverages, cosmetics, and therapies derived from plants. Centella asiatica is a plant often used as a source of antioxidants because it contains active compounds such as terpenoids, flavonoids, polyphenols, tannins, carotene, and vitamin C, which have antioxidant activity. In addition to containing 78% menthol, mint leaves contain resin and tannins, which are several polyphenolic antioxidants that prevent or neutralize the effects of free radicals. Antioxidants are compounds that can delay, slow down, or inhibit oxidation reactions and fight free radicals. The results showed that the antioxidant activity of the combination of Centela asiatica leaf extract and mint leaf extract based on the results of the analysis showed that it was included in the strong category.
Counseling on the Function of Vitamins in Increasing Body Endurance and Training on Hand Washing Movements, Wearing Masks, and Keeping Distance to the Marching Band Genta Bhuwana Ganeswara I Gusti Bagus Teguh Ananta; Dewa Gede Anom Anjasmara; Putu Indrayoni
Jurnal Abdimas ITEKES Vol 1 No 1 (2021): Jurnal Abdimas ITEKES Bali September
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37294/jai.v1i1.396

Abstract

Various preventive measures in tackling the increase in COVID-19 cases must be carried out, both by the government and the community. Preventive efforts are so far the best practice to reduce the impact of the COVID-19 pandemic, given that there is no treatment that is considered effective against the SARS-CoV-2 virus. One of the government's efforts to overcome the impact of the COVID-19 pandemic is by implementing the 3M movement, namely washing hands, wearing masks, and maintaining distance. Marching band is one of the art and sports learning activities that have been the impacted by the COVID-19 pandemic. Music learning methods in the classroom can be done online, but in practice mastery of musical instruments needs to be done offline. The offline training process needs to get more attention by implementing the 3M protocol, namely maintaining distance, using masks, and washing hands. Based on this, counseling activities on the function of vitamins were carried out in increasing endurance as well as training in washing hands, wearing masks, and keeping a distance. The implementation was carried out by conducting counseling and training which was attended by 25 participants. The results of the activity showed that there was an increase in the knowledge of the training participants regarding the COVID-19 pandemic and the movement to wash hands, wear masks and keep a distance, >80% of Marching Band members Genta Bhuwana Ganeswara had good knowledge.
Communication, Information and Education Iron Supplementation and Hemoglobin Putu Indrayoni; Sri Dewi Megayanti
Jurnal Abdimas ITEKES Vol 1 No 1 (2021): Jurnal Abdimas ITEKES Bali September
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37294/jai.v1i1.400

Abstract

nemia in young women can cause decreased concentration in learning, lack of enthusiasm in activities, decreased memory and decreased learning ability at school. National prevalence of anemia in Indonesia reaches 21.7%, with anemia sufferers aged 5-14 years of 26.4% and 18.4% of patients aged 15-24 years with the highest prevalence in women. Iron nutrition anemia in adolescents becomes dangerous if not handled properly, especially in preparation for pregnancy and childbirth when they are adults. The solution related to the problem of anemia in adolescents can be in the form of providing a refresher on knowledge about good nutritional intake for students providing iron supplementation and checking Hb levels in female students. To determine the change in knowledge in adolescent students, a pre and post test was conducted using a knowledge questionnaire about the importance of iron supplementation followed by measuring the status of the risk of anemia. The data shows that the pretest results are 71.43% with sufficient knowledge and the post test shows that 100% of students have good knowledge. From the results of Hb examination, it was found that the average Hb value of female adolescent students was 12.5 gr / dl with the lowest value 11.2 gr / dl and the highest value 14.7 gr / dl. From these data it can be seen that the provision of KIE FE supplementation is useful for students of SMK Kesehatan Panca Atma Jaya Klungkung.
Co-Authors AA Istri Mas Padmiswari Asthadi Mahendra Bhandesa, Asthadi Mahendra Dewa Gede Anom Anjasmara I Gusti Bagus Teguh Ananta Ida Ayu Manik Damayanti Kartiningsih, Ni Luh Putu Made Rismawan Nadya Treesna Wulansari Negara, I Gusti Ngurah Made Kusuma Sri Dewi Megayanti