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I Dewa Bagus Ketut Widya Pramana
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HBA1C SEBAGAI KANDIDAT BIOMARKER UNTUK PREDIKSI PROGESIVITAS GANGGUAN KOGNITIF TERKAIT DIABETES MELITUS TIPE 2 Putri Nurhayati; Achmad Mujahidin Irham; I Dewa Bagus Ketut Widya Pramana; Herpan Syafii Harahap
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.517

Abstract

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia which underlie its complications, including cognitive impairment. T2dm-associated cognitive impairment is generally characterized by the decrease in at least one cognitive domain. However, its progression can be slowed by appropriate blood glucose control. Hb1Ac is a candidate of appropriate biomarker in predicting the progression of T2DM-associated cognitive impairment. This is based on several important characteristics it has, including a good blood glucose index, low daily biological variability, relatively unaffected by stress conditions, and unaffected by variations due to loading the amount of glucose.