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All Journal Zenit Journal of Islamic Medicine Prosiding SENTIKUIN (Seminar Nasional Teknologi Industri, Lingkungan dan Infrastruktur)
Rahma Micho Widyanto
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Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Education Energy Engineering Industrial & Manufacturing Engineering Medicine & Pharmacology

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Sel Punca sebagai Transformasi Alternatif Terapi Widowati, Wahyu; Widyanto, Rahma Micho
Zenit Vol 2, No 1 (2013)
Publisher : Zenit

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Abstract

Stem cells are cells that became the beginning of the growth  to others cell that constract the whole body of organisms, including human. Stem cells are from embryonic, fetal, or adult cells, which are capable to proliferate to cells in a long time, which this cell doesn’t have specific function, stem cells are able to differentiate  into specific cell that build tissues and organ systems. Stem cells have charateristic including :  undifferentiated cells, this cell is self-renewal, cells can differentiate into more than one type of cells (multipotent/pluripotent). Types of stem cells include embryonic stem cells derived from embryo, or inner cell mass (ICM) and adult stem cells found in bone marrow, cord blood, umbilical cord, peripheral blood, liver, skin, brain, dental pulp, fatty tissue. The uniqueness of stem cells give new hope as an alternative therapy or cells therapy for various types especially degenerative diseases. Keywords: stem cell, cell therapy
Metode untuk Mempertahankan Kandungan Nitrit Sarang Burung Walet Selama Penyimpanan Utomo, Budi ; Widyaratri, Yuni ; Widyanto, Rahma Micho
Prosiding SENTIKUIN (Seminar Nasional Teknologi Industri, Lingkungan dan Infrastruktur) Vol 1 (2018): PROSIDING SENTIKUIN
Publisher : Fakultas Teknik Universitas Tribhuwana Tunggadewi

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Abstract

Wallet bird nest is a nest that can be consumed by humans, which is made from male swallow's saliva. Male swallow bird makes a nest with its saliva for 35 days. The purpose of this study was to determine the number of TPC (Total Plate Count), nitrite and L * a * b. The material of this study is wallet bird's nest. The method used is Completely Randomized Design (CRD) with 3 treatments and 4 replications P0 = Without treatment, P1 = room temperature, P2 = Freezer no vacuum, P3 = Vacuum freezer. The results showed that the best TPC test results obtained by room temperature treatment were 461.25 ? 39.167 x 104, and the best nitrite test was obtained in vacuum freezer treatment ie 1.42 ? 0.059, and the best L * a * b color test on room temperature treatment 1.50 ? 0.520. Conclusion of the results of this study is the best treatment in this study is the storage of swallow's nests at freezer temperature using vacum packaging seen from the TPC parameters, nitrite and redness level using the L * a * b * color meter instrument.
Antioxidant and Cytotoxic Effect of Water Extract of Ananas comosus in Human Breast Cancer Cell Line Widyanto, Rahma Micho; Halimah, Ririt Nafi'; Rahmi, Yosfi; Utomo, Budi; Proborini, Wahyu Diah; Yunimar, Yunimar
Journal of Islamic Medicine Vol 4, No 2 (2020): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2020
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v4i2.10109

Abstract

Background: Breast cancer is the most common type of cancer and the second leading cause of death in the world. One of the supporting therapeutic efforts to overcome cancer is through food, mainly fruits. Ananas comosus has been investigated for its potential as an anti-cancer. It is a source of antioxidants from the content of Vitamin C and flavonoids that work by capturing free radicals, resulting in inhibition of cancer cell proliferation.Objective :This study was conducted to determine the antioxidant activity and cytotoxicity of water extract of Ananas comosus on T-47D breast cancer cell lines.Method: The process of extracting pineapple flesh is done using water as a solvent, then tested its antioxidant activity using DPPH and cytotoxicity using MTT assay on T-47D.Result: IC50 value for antioxidant activity was 463.369 μg / mL and the IC50 for the cytotoxicity assay was 488.003 μg / mL.Conclusion : The water extract of Ananas comosus have very weak antioxidant activity and moderate cytotoxicity properties that have potential as chemo preventive agents in T-47D breast cancer cell lines.
Co-Authors Budi Utomo Halimah, Ririt Nafi' Proborini, Wahyu Diah WAHYU WIDOWATI Widyaratri, Yuni Yosfi Rahmi YUNIMAR YUNIMAR