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All Journal Majalah Farmaseutik Jurnal Sains dan Kesehatan
Putri Dina Mahera Laily
Universitas Gadjah Mada
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Laporan Kasus: Terapi Covid-19 pada Pasien dengan Komorbid Hipertensi: Case Report: Covid-19 Therapy in Patients with Comorbid Hypertension Putri Dina Mahera Laily
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 2 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (284.732 KB) | DOI: 10.25026/jsk.v4i2.914

Abstract

Corona Virus Desease 2019 (COVID-19), is a disease caused by corona virus. According to the World Health Organization (WHO), COVID-19 is a tragedy in the world of global health. The main clinical manifestations are cough, fever, shortness of breath and in some cases can cause multiple organ failure, septic shock and metabolic acidosis which is difficult to correct. Where people who are elderly and have chronic disease generally have a poor prognosis. Prompt and appropriate therapy is expected to save patients. Until now, scientific evidence regarding the effectiveness and safety of these therapies is still very little. This study aims to evaluate the effectiveness and safety of COVID-19 therapy in COVID-19 patients with comorbid hypertension. The therapy used in this patient was azithromicin, ceftriaxone, levofloxacin and meropenem; Antiviral therapy was given hydroxychloroquine; symptomatic therapy for fever was given paracetamol; hypertension therapy was given amlodipine; Support therapy was given salbutamol and dexamethasone; Additional therapy was given vitamin C 1000 mg / 24 hours, and zinc. There was no worsening effect on the patient after receiving this therapy. Patients get treatment at RSUP Dr. Sardjito then was discharged after treatment without any complaints and with PCR swabs were negative results. Keywords: Therapy, COVID-19, Comorbid, Hypertensi
The Use of Antibiotics in COVID-19 Therapy in RSUP Dr. Sardjito Yogyakarta Putri Dina Mahera Laily; Tri Murti Andayani; Ika Puspitasari
Majalah Farmaseutik Vol 19, No 1 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v19i1.71638

Abstract

As a newly emerging disease initially identified at the end of 2019 in Wuhan, China, COVID-19 has various therapeutic options. The current COVID-19 treatment in Indonesia refers to the licensed treatment based on the Emergency Used Authorization from BPOM, which lists many approved antibiotic therapies. However, inappropriate use of antibiotics is known to have an adverse impact of resistance. Therefore, studies on the use of antibiotics in health care facilities, including hospitals, are pivotal, especially in the management of newly emerging disease of COVID-19. This study aims to describe the use of antibiotics as a therapeutic option for COVID-19 treatments in RSUP Dr. Sardjito Yogyakarta. The research used descriptive analytic method by involving patients, who were tested positive for COVID-19 in the period of February to September 2020 in Dr. RSUP Sardjito Yogyakarta, as the research subjects. Data were collected retrospectively using the drug use listed in the medical records. Data were analyzed based on patient characteristics, antibiotic profile, and final prognosis of treatment outcome. This study revealed that the highest cases occurred in men with 69.4%. The productive age group of 21 to 60 years old was known to be the age group with the highest COVID infection (64%). The most widely used antibiotics were azithromycin (56.5%) and levofloxacin (32.9%). The use of antibiotic therapy in COVID-19 patients at RSUP Dr. Sardjito Yogyakarta has proven to be quite effective with a prognostic rate of 76.5% for patients experiencing recovery.
Co-Authors Ika Puspitasari Tri Murti Andayani