Background: Regulating pregnancy spacing can prevent maternal and infant mortality. Pregnancy during the pandemic is also considered risky because many health facilities are filled with Covid-19 patients, which can cause excessive anxiety in mothers. Mother's lack of interest in using IUD contraception is influenced by several factors, including the level of knowledge and attitudes. The purpose of this study was to determine the effect of IUD family planning education on the knowledge, attitudes and interests of family planning acceptors during the Covid-19 pandemic at the Makassar City Regional General Hospital. Methods: This type of research is quantitative with a quasi-experimental research design with a one group pretest posttest design approach. The population in this study were all postpartum mothers at the Makassar City Regional General Hospital as many as 186 people. The number of samples is 51 people using the Lameshow formula. The sampling technique used purposive sampling with statistical tests using the Nonparametric Wilcoxon Test. Results: The results of the Wilcoxon Rank Test obtained a p-value of 0.000 (<0.05), meaning that there was an effect of providing IUD family planning education on increasing knowledge, attitudes and interests of family planning acceptors during the Covid-19 pandemic at the Makassar City Regional General Hospital. Conclusion: Suggestions in the study are that mothers who already have a positive attitude are expected to use the IUD to suppress pregnancy and childbirth during the Covid-19 pandemic as an effort to reduce maternal and infant mortality. As well as the mother's family, especially the husband, to always provide support and motivation to further strengthen his intention to use the IUD.