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All Journal Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan
Myra Puspha Hardina
Laboratorium Penelitian dan Pengembangan Kefarmasian "Farmaka Tropis", Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Profil Kromatografi Senyawa Aktif Antioksidan dan Antibakteri Fraksi N-Heksana Daun Libo (Ficus variegata Blume) Rolan Rusli; Myra Puspha Hardina; Fairul Muflihah; Agung Rahmadani
Journal of Tropical Pharmacy and Chemistry Vol. 3 No. 2 (2015): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.666 KB) | DOI: 10.25026/jtpc.v3i2.98

Abstract

Research about chromatographic profile of antioxidant and antibacterial compounds in n-hexane fraction of Libo leaves (Ficus variegata Blume.) has been done in order to know the form of chromatographic profile of antioxidant and antibacterial compounds in n-hexane fraction of Libo leaves. Extraction was done by maceration using methanol. Isolation was done by 2 methods, vacuum liquid chromatography (VLC) then followed by conventional column chromatography. Eluent used are n-hexane-ethyl acetate and methanol-chloroform. The results based on conventional column chromatography are as many as 10 fractions. The fractions are being conducted then by a qualitative testing of the antioxidant activity using DPPH method and antibacterial activity test using bioautography TLC method. The results formed as a chromatographic profile of fraction that contain antioxidant and antibacterial activity, which are as many as 5 fractions (NHB1, NHB3, NHB4, NHC1, NHC3) active as an antioxidant and 4 fractions (NHB1, NHC1, NHC2, NHC3) which are active as an antibacterial. The secondary metabolite contents of the fractions are alkaloid, flavonoid and steroid/terpenoid.
Analisis Secara GC-MS Senyawa Aktif Antioksidan Fraksi N-Heksana Daun Libo (Ficus variegata Blume) Vina Maulidya; Myra Puspha Hardina; Lizma Febrina; Rolan Rusli; Agung Rahmadani
Jurnal Sains dan Kesehatan Vol. 1 No. 10 (2018): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.956 KB) | DOI: 10.25026/jsk.v1i10.101

Abstract

Tanaman Libo (Ficus variegata Blume) merupakan salah satu tumbuhan liar khas Kalimantan Timur sebagai sumber bahan larvasida dan antioksidan. Penelitian bertujuan untuk mengetahui komponen senyawa aktif antioksidan dalam fraksi n-heksana daun Libo dengan metode GC-MS. Interpretasi spektrum GC-MS dilakukan menggunakan database standar National Institute Standard and Technology (NIST). Komponen mayor fraksi n-heksana yang memiliki aktivitas antioksidan antara lain: cyclotetracosane; 1-heneicosanol; 1-docosene; 1,2-benzenedicarboxilic acid; 1-heptacosanol; octacosanol; dan cyclooctacosane.
Co-Authors Agung Rahmadani Fairul Muflihah Lizma Febrina Rolan Rusli Vina Maulidya