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Nurhayati Masloman
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Toxoplasma gondii immunoglobulin G in paired infant-and-mother sera Ayling Sanjaya; Nurhayati Masloman; Rocky Wilar; Josef Tuda
Paediatrica Indonesiana Vol 49 No 2 (2009): March 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.829 KB) | DOI: 10.14238/pi49.2.2009.65-8

Abstract

Background  Toxoplasmosis  is  a worldwide zoonotic diseasecaused  by  Toxoplasma  gondii.  Congenital toxoplasmosis (CT)is  the  result  of  vertical transmission  during  pregnancy  thatmay cause pathologic effects  on  the newborn such  as  classicaltriad  of  congenital toxoplasmosis.  Newborn  humans  are  notimmunologically  competent  and the infant must be protected  by passive lgG antibodies  that  are selectively transported across the placenta during development.  We  studied the transfer  of  passive lgG from the  mother  to developing infant using blood specimen taken from the infant within one  month  of  birth.Objective  To  determine the seropositivity  of  lgG to  T.  gondii  in paired sera  of  infants and mothers.Methods  A cross sectional study was carried  out  on  50 pairedsera  of  infants  of  less  than  one  month  of  age and their mothers. The  study was carried  out  between November 2007 and January 2008  at  Prof.  R.  D.  Kandou Hospital in Manado.  T.  gondii  lgG was detected using the Latex Agglutination method.  The  seropositivity ofT.  gondii  lgG was analyzed descriptively.Results  A total  of  28 mothers from 50 infant-mother pairs wereseropositive for  T.  gondii  IgG.  Of  the 28 seropositive mothers, 22  of their paired infants were seropositive.  The  remaining six seropositive mothers  had  infants  that  were  not  seropositive for T.  gondii.Conclusions  The  identification  of  seropositive lgG for  T.  gondii in infants less  than  one  months  age indicates  that  the lgGs in infants are mostly derived from their mothers.  CT  must be considered  and  further  examinations  are needed.
Correlation between leukocyte aggregation score of cerebrospinal fluid and bacterial meningitis in children Meitha PE Togas; Nurhayati Masloman
Paediatrica Indonesiana Vol 44 No 2 (2004): March 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.354 KB) | DOI: 10.14238/pi44.2.2004.61-5

Abstract

Background Bacterial meningitis is one of life-threatening dis-eases and carries a risk of sequelae in affected children. In termsof cost and rapid differentiation between bacterial and non-bacte-rial meningitis, several tests have been proposed.Objective This study aimed to determine the use of leukocyteaggregation score (LAS) of cerebrospinal fluid (CSF) in diagnos-ing bacterial meningitis.Methods A prospective analytic study was done from October 2001to July 2002 in the Department of Child Health, Medical School,Sam Ratulangi University/ Manado General Hospital. Children pre-senting with symptoms of meningitis, aged between 28 days and13 years were enrolled. LAS was counted in percentage. Regres-sion analysis was used to determine the correlation between LASand diagnosis of bacterial meningitis.Results CSF examinations were done on 35 meningitis patients.Three patients were excluded. The remaining 32 patients com-prised of 11 with bacterial meningitis and the other 21 with non-bacterial meningitis. The mean of LAS in bacterial meningitis wassignificantly higher than that of non-bacterial meningitis (p<0.001).The cut off value of LAS to diagnose bacterial meningitis was12.35%.Conclusion LAS may be used as a fast and simple alternativediagnostic tool to confirm the diagnosis of bacterial meningitis
Japanese encephalitis in children Nurhayati Masloman; H S Widarso; W Cicilia
Paediatrica Indonesiana Vol 45 No 1 (2005): January 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.042 KB) | DOI: 10.14238/pi45.1.2005.46-8

Abstract

Japanese encephalitis is a zoonotic disease causedby Japanese encephalitis virus, attacking domesticanimals, mainly pigs and birds. It is transmittedto humans by mosquito bites, namely Culextritaeniorhyncus.
The association between nutritional status and motor development in children under five years old Nurhayati Masloman; Stefanus Gunawan
Paediatrica Indonesiana Vol 45 No 3 (2005): May 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.3.2005.107-10

Abstract

Background Severe malnutrition in children is closely related todelayed physical growth and mental development. Very few re-ports mention the effects of mild to moderate malnutrition on mo-tor development.Objective The objective of this study was to determine the rela-tionship between nutritional status and motor development in earlychildhood.Methods In this cross-sectional study, we examined body weightof children under 5 years of age, the ability to sit or walk withoutsupport, and parachute sign in those under 2 years of age whocame to community child health surveillance posts in TumintingSubdistrict, Manado, Indonesia.Results Among 359 under-five children, 296 were well-nourishedand 63 had mild to moderate malnutrition. The ability to sit withoutsupport in malnourished children was significantly delayed com-pared to that in well-nourished ones (P=0.03). The ability to walkwithout support and parachute sign were not significantly differentbetween the two groups.Conclusion The ability to sit without support in children with mildto moderate malnutrition is delayed compared to that in well-nour-ished ones
Co-Authors Ayling Sanjaya H S Widarso Josef Tuda Meitha PE Togas Rocky Wilar Stefanus Gunawan W Cicilia