Nurhayana Sennang, Nurhayana
Bagian Ilmu Patologi Klinik FK UNHAS–BLU RS DR Wahidin Sudirohusodo, Makassar,

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POLA KUMAN AEROB DAN KEPEKAAN ANTIMIKROBA PADA ULKUS KAKI DIABETIK Kurniawan, Liong Boy; Esa, Tenri; Sennang, Nurhayana
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 18, No 1 (2011)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v18i1.357

Abstract

Diabetic foot ulcer is a common complication of diabetic disease which causes morbidity and foot amputation. One major pathogenesis is infection. Microbes which infect are varied. The use of inappropriate antimicrobials can or may cause drugs resistance. Data of microbes pattern and sensitivity test is important and may guide the clinician in giving the initial therapy. The aim of this retrospective study was to know the characteristics, microbial pattern, and the sensitivity to antimicrobial drugs of 31 diabetic foot ulcer patients who were hospitalized at Wahidin Sudirohusodo Hospital, Makassar in the period of January 2009 until June 2010. The study results showed the age mean was 54.06±12.4 years old, and the onset of diabetes mellitus was 7.62±5.77 years. The common microbes were gram negative bacteria (73.52%) including Enterobacter agglomerans, Proteus mirabilis and Klebsiella pneumonia, while the most common gram positive microbe was Streptococcus sp. Gram positive microbes were sensitive to meropenem, ceforoxim and amoxilin, while Gram negative microbes were sensitive to meropenem. Based on this study, the researchers concluded that the most common microbes which infect the feet were gram negative microbes. Gram positive microbes were still sensitive to meropenem, ceforoxim and amoxilin. Gram negative microbes were sensitive to meropenem.
Hasil Positif Palsu Tes Morfin pada Skrining Urin Narkoba Diduga Akibat Rifampisin Kurniawan, Liong Boy; Widaningsih, Yuyun; Sennang, Nurhayana; Bahrun, Uleng; Arif, Mansyur
Cermin Dunia Kedokteran Vol 42, No 1 (2015): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.256 KB) | DOI: 10.55175/cdk.v42i1.1054

Abstract

Hasil positif palsu pada tes skrining urin narkoba dengan metode imunologi jarang terjadi. Pemastian hasil memerlukan anamnesis yang baik mengenai konsumsi obat dan konfirmasi dengan tes yang lebih spesifik, biasanya dengan metode kromatografi gas/spektrometri massa. Beberapa substansi dilaporkan dapat menyebabkan hasil positif palsu. Dilaporkan satu kasus laki-laki 18 tahun dengan hasil positif morfin (tes urin narkoba) menggunakan metode imunologi kompetitif. Setelah anamnesis ketat diketahui bahwa pasien tersebut dalam pengobatan rifampisin selama 6 bulan karena tuberkulosis dan tidak pernah mengkonsumsi narkoba. Sampel urin berwarna kemerahan (hasil ekskresi metabolit rifampisin melalui urin). Diperlukan konfirmasi pasti dengan metode lebih spesifik dengan kromatografi gas/spektrometri massa (standar baku emas).False positive reports on urine drug screening using immunoassay method are rare. Confirmation should be done through detailed anamneses on consumed drugs that may interfere result and perform test with more specific method such as gas chromatography/mass spectrometry (GC-MS). Some substances have been reported as the causes of false positive test. A case reported to have positive on morphine urine drug test using competitive immunoassay from an 18 year-old male. The patient was on 6-month rifampicin treatment for tuberculosis and had no history of substance abuse. The urine sample was reddish due to rifampicin metabolite excretion. Confirmation with gas chromatography/mass spectrometry method should be performed as gold standard.
GIARDIASIS Harun, Haerani; Sennang, Nurhayana; Rusli, Benny
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 5 No. 3 (2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (657.736 KB) | DOI: 10.22487/htj.v5i3.125

Abstract

Giardiasis merupakan salah satu penyakit gastrointestinal yang banyak menyerang di negara berkembang yang disebabkan oleh parasit Giardia lamblia. Penyakit ini umumnya menyerang orang orang yang berkemah dan minum air dari sungai yang terkontaminasi. Infeksi ini juga menyerang anak-anak yang rentan terhadap penularan parasit ini. Penelitian Simadibrata pada tahun 2004 menunjukkan prevalensi Giardiasis di Indonesia sebesar 3.62%, sedangkan dari anak-anak yang menderita diare di Malang 1.2% diantaranya disebabkan oleh Giardiasis. Artikel ini bertujuan memberi gambaran tentang penyakit Giardiasis mulai dari etiologi, pathogenesis hingga pengobatan. Selain itu dipaparkan pula beberapa pemeriksaan yang dapat dilakukan untuk mendeteksi giardiasis.