Article Per Year (5 Year)
p-Index From 2019 - 2024
0.23
P-Index
This Author published in this journals
All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Aulia Rizka
Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Sarcopenia are Associated with Poor Performance Status in Indonesian Patients with Hepatocellular Carcinoma Hendra Koncoro; Irsan Hasan; C Rinaldi Lesmana; Humala Prika Aditama; Thariqah Salamah; Aulia Rizka; Edy Rizal Wahyudi; Hamzah Shatri
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.006 KB) | DOI: 10.24871/231202217-23

Abstract

Background: Sarcopenia affects hepatocellular carcinoma (HCC) prognosis. Sarcopenia can be assessed by using skeletal muscle index (SMI), measured on transverse CT images at the third lumbar vertebra (L3). HCC staging consists of liver function assessment and Eastern Cooperative Oncology Group performance status (ECOG-PS).                   ECOG-PS can reflect physical function. This study was aimed to describe the proportion of sarcopenia among adults, using Japan Society of Hepatology criteria and explore association between sarcopenia and poor performance status.Method: The study was conducted in a tertiary hospital during January – October 2021. SMI were evaluated using computed tomography images of L3 in 85 HCC patients. Clinical, laboratory and body composition data were analyzed using bivariate analysis. Logistic regression was performed to obtain an independent association between ECOG-PS and sarcopenic status of HCC patients.Results: Eighty-five HCC patients (median age, 52 years) were analyzed. Sarcopenia was observed in 49,4% of HCC patients. On multivariate binary regression analysis, a poor ECOG-PS remained independently associated with sarcopenia in HCC (adjusted OR = 4.169 (CI 95% = 1.504-11,555), p 0,006).Conclusion: Sarcopenia has high proportion in HCC patients. There were strong association between ECOG-PS and sarcopenia in HC.
Co-Authors C Rinaldi Lesmana Edy Rizal Wahyudi Hamzah Shatri Hendra Koncoro Humala Prika Aditama Irsan Hasan Thariqah Salamah