Article Per Year (5 Year)
p-Index From 2019 - 2024
0.61
P-Index
This Author published in this journals
All Journal Bandung Conference Series : Medical Science
Uci Ary Lantika
Unknown Affiliation
Humanities Medicine & Pharmacology Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Hubungan antara Pemberian Remdesivir dan Durasi Rawat Inap Dibandingkan Favipiravir pada Pasien Covid-19 Alhilal Hamdi M.Nur; Heni Muflihah; Uci Ary Lantika
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.755

Abstract

Abstarct. One of the pharmacological treatments for COVID-19 recommended by the World Health Organization (WHO) is remdesivir. Based on the Indonesian COVID-19 management manual, among the antivirals used are remdesivir and favipiravir. Remdesivir is indicated for severe patients, while favipiravir is indicated for moderate to severe patients. The selection of remdesivir or favipiravir based on clinical characteristics and benefits in COVID-19 patients in Indonesia has not been widely carried out. The benefits of pharmacological therapy in hospitalized COVID-19 patients can be seen, one of which is based on the duration of hospitalization. This study aimed to analyze the relationship between remdesivir use and duration of hospitalization compared to favipiravir in hospitalized COVID-19 patients. This study is a retrospective observational analytic study using medical record data. The subjects of this study were hospitalized COVID-19 patients at Al-Ihsan Hospital for the period December 2020 to March 2021. The data studied included clinical characteristics, oxygen saturation (SpO2), administration of remdesivir or favipiravir therapy, and duration of hospitalization. The subjects of this study were 102 people, consisting of 51 people in the remdesivir group and 51 people in the favipiravir group. Remdesivir is mostly given to patients aged > 50 years (72.5%) while favipiravir is mostly used in patients aged 18-50 years (53%). Severe grade patients (SpO2 <90%) had a median duration of hospitalization of 11 days, while non-severe patients (SpO2 >90%) had a median of 9 days. The remdesivir group had a median duration of hospital stay of 10 days while that of favipiravir was 11 days. Statistically there was no association between remdesivir administration and duration of hospitalization compared to favipiravir in COVID-19 patients (p-value = 0.2436). Remdesivir did not provide a clinical improvement in the duration of hospital stay when compared with favipiravir. Abstrak. Salah satu tatalaksana farmakologi COVID-19 yang dianjurkan World Health Organization (WHO) adalah remdesivir. Berdasarkan buku pedoman tatalaksana COVID-19 Indonesia, diantara antivirus yang digunakan adalah remdesivir dan favipiravir. Remdesivir diindikasikan untuk pasien derajat berat, sedangkan favipiravir untuk pasien derajat tidak berat sampai berat. Pemilihan jenis antivirus remdesivir atau favipiravir berdasarkan karakteristik klinis dan manfaatnya pada pasien COVID-19 di Indonesia belum banyak dilakukan. Manfaat terapi farmakologi pada pasien COVID-19 rawat inap dapat dilihat salah satunya berdasarkan durasi rawat inap. Penelitian ini bertujuan untuk menganalisis hubungan penggunaan remdesivir dan durasi rawat inap dibandingkan favipiravir pada pasien COVID-19 rawat inap. Penelitian ini merupakan penelitian analitik observasional retrospective menggunakan data rekam medik. Subyek penelitian ini adalah pasien COVID-19 rawat inap di RSUD Al-Ihsan periode Desember 2020 sampai Maret 2021. Data yang diteliti meliputi karakteristik klinis, saturasi oksigen (SpO2), pemberian terapi remdesivir atau favipiravir, dan durasi rawat inap. Subyek penelitian ini berjumlah 102 orang yang terdiri dari 51 orang kelompok terapi remdesivir dan 51 orang kelompok favipiravir. Remdesivir banyak diberikan pada pasien berusia > 50tahun (72.5%) sedangkan favipiravir banyak digunakan pada usia 18-50 tahun (53%). Pasien derajat berat (SpO2 <90%) memiliki durasi rawat inap dengan median 11 hari sedangkan pasien derajat tidak berat (SpO2 >90%) memiliki median 9 hari. Kelompok terapi remdesivir memiliki median durasi rawat inap 10 hari sedangkan favipiravir 11 hari. Secara statistik tidak terdapat hubungan antara pemberian obat remdesivir dan durasi rawat inap dibandingkan favipiravir pada pasien COVID-19 (p-value = 0.2436). Remdesivir tidak memberikan perbaikan klinis durasi raawat inap jika dibandingkan dengan favipiravir.
Scoping Review: Efektivitas Pengonsumsian Probiotik terhadap Berat Badan pada Overweight dan Obesitas Dewasa Salsa Bila Yunisa Tri Utami; Uci Ary Lantika; Ami Rachmi
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.908

Abstract

Abstract. Obesity is a condition of excess fat accumulation due to an imbalance of energy intake and energy expenditure over a long period of time. According to the WHO, a person is diagnosed overweight if their Body Mass Index (BMI) 23-24,9 and obese if IMT ≥30. Probiotic consumption is one of management to encountered that condition. Probiotics have physiological function that contribute to food intake and appetite, weight loss, and metabolic function via gut microbiota. The purpose of this study was to determine the effectiveness of consuming probiotics on the body weight in adult obese conditions. This study was Scoping Review, by searching for articles from the PubMed, Springer Link, and Science Direct databases with keywords used probiotic and body weight and adult obesity randomized controlled trial ini the period 2019-2021. Articles that meet the inclusion criteria are 308 articles and those that are included in the exclusion criteria are 303 articles. From the results of the feasibility test based on on PICOS, 4 articles were obstained. The results of the analysis of 4 articles, there were 3 articles that state that the consumption of probiotics can lose body weight and more effectively if accompanied by a balanced diet and physical activity. In addition, there is 1 article that shows that the consumption of probiotic supplementation does not provide any difference between the intervention and control groups. As conclusion of this study is that the consumption of probiotics can lose body weight in overweight and obesity. However, this consumption must be accompanied by a balanced diet and physical activity. Abstrak. Obesitas adalah kondisi terjadinya penimbunan lemak berlebih akibat dari ketidakseimbangan asupan energi dan pengeluaran energi dalam jangka waktu yang panjang. Menurut WHO, seseorang dinyatakan overweight jika Indeks Massa Tubuh (IMT) 23-24,9 dan obesitas jika IMT ≥30. Untuk pemilihan makanan yang tepat dalam membantu menanggulangi kondisi overweight dan obesitas, salah satunya adalah pengkonsumsian probiotik. Probiotik memiliki salah satu fungsi fisiologis yang berkontribusi dalam kesehatan mikrobiota usus yang dapat mempengaruhi asupan makanan dan nafsu makan, berat badan serta fungsi metabolisme melalui jalur gastrointestinal. Tujuan penelitian ini adalah untuk mengetahui efektivitas pengkonsumsian probiotik terhadap berat badan pada kondisi overweight dan obesitas dewasa. Penelitian ini merupakan Scoping Review, dengan mencari artikel dari database PubMed, Springer Link, dan Science Direct dengan keyword yang digunakan Probiotic AND body weight AND adult obesity randomized controlled trial dalam jangka waktu 2019-2021. Artikel yang sesuai dengan kriteria inklusi sebanyak 308 artikel dan yang termasuk dalam kriteria eksklusi sebanyak 303 artikel. Hasil uji kelayakan berdasarkan PICOS sebanyak 4 artikel. Hasil analisis dari 4 artikel, terdapat 3 artikel yang menyatakan bahwa pengonsumsian probiotik dapat menurunkan berat badan dan lebih efektif jika dibarengi diet dan aktivitas fisik yang seimbang. Selain itu, terdapat 1 artikel yang menunjukan bahwa pengkonsumsian suplementasi probiotik tidak memberikan adanya perbedaan antara kelompok intervensi dan kontrol. Kesimpulan dari penelitian ini adalah pengonsumsian probiotik dapat menurunkan berat badan pada overweight dan obesitas. Namun demikian, pengkonsumsian ini harus dibarengi dengan diet dan aktivitas fisik yang seimbang.
Scoping Review: Suplementasi Probiotik Efektif Menurunkan Kadar IL-6 pada Obesitas Dewasa Pipit Anggana Dewi; Uci Ary Lantika; Ajeng Kartika Sari
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6530

Abstract

Abstract. Obesity is ranked fifth as a primary health problem in the world. Obesity is abnormal fat accumulation caused by a long-term imbalance between energy intake and energy use. This energy imbalance causes excess adipose accumulation. Adipose tissue functions to produce cytokines such as IL-6. Increased cytokine production creates a chronic proinflammatory state. Obesity management can be carried out with multimodal lifestyle interventions such as changes in diet, including controlled food portions and healthy foods such as probiotics. Probiotics have a mechanism of action, namely immunomodulation, so that they can reduce the production of cytokines such as IL-6. The purpose of this study was to analyze whether probiotic supplementation is effective in reducing IL-6 levels in obese adult patients. This research uses a scoping review study to identify, analyze, and evaluate scientific writing through Pubmed, ScienceDirect, and SpringerLink data sources that meet the inclusion, exclusion, and eligibility criteria using the JBI Critical Appraisal Checklist summarized in the PRISMA diagram. 4,309 articles were produced from the three data sources, 526 articles met the inclusion criteria, and 5 articles met the exclusion and eligibility criteria. The results of three articles stated that probiotic supplementation was effective for reducing IL-6 levels in adults with obesity, while two articles stated that there were no significant changes. Two articles stated that there was no significant change in IL-6 levels were studies using synbiotics, which consisted of prebiotics and probiotics, while three other research articles using only probiotics stated that there was a decrease in IL-6 levels. Abstrak. Obesitas menduduki peringkat kelima sebagai masalah kesehatan primer di dunia. Obesitas diartikan akumulasi lemak abnormal disebabkan oleh ketidakseimbangan jangka panjang antara asupan energi dan penggunaan energi. Ketidaksimbangan energi tersebut menimbulkan akumulasi adiposa berlebih. Jaringan adiposa berfungsi menghasilkan sitokin seperti IL-6. Peningkatan produksi sitokin menimbulkan keadaan proinflamasi kronis. Manajemen obesitas dapat dilakukan dengan multimodal lifestyle intervention seperti perubahan pola makan termasuk porsi makanan terkontrol serta makanan sehat seperti probiotik. Probiotik memiliki mekanisme aksi yaitu imunomodulasi sehingga dapat menurunkan produksi sitokin seperti IL-6. Tujuan penelitian ini untuk menganalisis apakah suplementasi probiotik efektif menurunkan kadar IL-6 pada pasien obesitas dewasa. Penelitian menggunakan studi scoping review untuk mengidentifikasi, menganalisis, dan mengevaluasi tulisan ilmiah melalui sumber data Pubmed, ScienceDirect, dan SpringerLink yang memenuhi kriteria inklusi, ekslusi dan kelayakan menggunakan JBI Critical Apprasial Checklist dirangkum dalam diagram PRISMA. Dihasilkan 4.309 artikel dari ketiga sumber data, 526 artikel memenuhi kriteria inklusi dan 5 artikel memenuhi kriteria ekslusi dan kelayakan. Hasil dari 3 artikel menyatakan suplementasi probiotik efektif untuk menurunkan kadar IL-6 pada orang dewasa dengan obesitas, sedangkan 2 artikel menyatakan tidak ada perubahan yang signifikan. Dua artikel yang menyebutkan tidak ada perubahan signifikan kadar IL-6 merupakan penelitian menggunakan sinbiotik yaitu terdiri dari prebiotik dan probiotik sedangkan 3 artikel penelitian lainnya hanya menggunakan probiotik menyebutkan terdapat penurunan kadar IL-6.
Co-Authors Ajeng Kartika Sari Alhilal Hamdi M.Nur Ami Rachmi Heni Muflihah Pipit Anggana Dewi Salsa Bila Yunisa Tri Utami