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All Journal Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana (JUFDIKES) Jurnal Pengabdian Ilmu Kesehatan Jurnal Sains dan Kesehatan Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Aulia Debby Pelu
Sekolah Tinggi Ilmu Kesehatan Maluku Husada
Health Professions Medicine & Pharmacology Public Health

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FORMULASI MINYAK GOSOK DARI BIJI PALA (Myristica fragrans) DAN UJI ANTIBAKTERI TARHADAP BAKTERI Staphylococcus aureus Jayanti Djarami; Aulia Debby Pelu; Sardila Bugis
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 2 No. 1 (2020): Januari : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v2i1.152

Abstract

Nutmeg is known as a spice plant that has economic value and multipurpose because every part of the plant can be used in various industries. Compounds contained in nutmeg seeds include essential oils, a-pinene, b-pinene, limonene, myristicin, safrole, and methyl eugenol. Nutmeg plant nutritious as antidiarrheal, antidiabetic, antimicrobial. The purpose of this study was to make a formulation of rubbing oil and to determine the bacteriostatic activity of nutmeg seed oil on staphylococcus aureus bacteria. This study used three formulations, namely the provision of distilled water as a negative control, chloramphenicol as a positive control. The method used in this research is the well method. Bacteria that were incubated for 24 hours in the fastest concentration inhibition research were at 50% concentration because of bacterial growth which showed that the higher the concentration, the higher the inhibitory power and at 20% concentration the results were resistant, because the amount of solvent used was higher. low and can not inhibit the growth of microorganisms.
Formulasi Sediaan Salep Ekstrak Etanol Daun Cengkeh (Syzygium aromaticum folium) Dengan Variasi Konsentrasi Basis Hidrokarbon Jayanti Djarami; Aulia Debby Pelu; Dwi Sintya Karubaba
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 2 No. 1 (2020): Januari : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v2i1.153

Abstract

Clove plant (Syzygium aromaticum. L) Is one of the plants known by the people in Bula village as a traditional medicine the leaves of cloves (Syzygium aromaticum folium) are often used as an alternative to cure stiff and rheumatic diseases such as causing pain due to excessive activity, so that it can be used as an active ingredient in making ointments The purpose of this study was to identify the chemical content of clove leaves (Syzygium aromaticum folium) from Bula village and to formulate a good and stable clove leaf ethanol extract ointment (Syzygium aromaticum folium) using a ratio of variations in the concentration of the Hydrocarbon Base. This research method is experimental which was carried out using a combination base of vaseline album: cera alba from three different formulations with a concentration ratio of F1 (76%: 10 %), F2 (71%: 15%), F3 (66%: 20%), each formulation contains 10% ethanol extract of clove leaf (Syzygium aromaticum folium). Evaluation of ointment preparations was carried out after 1 week of storage; evaluation tests included organoleptic tests, homogeneity tests and pH tests. The results showed that the ointment preparations F1 (76%: 10%) met the requirements for a good and stable ointment, while F2 (71%: 15%), and F3 (66%: 20%) did not meet the requirements for a good and stable ointment.
Uji Fisik Formulasi Hand Sanitizer Dengan Bahan Aktif Daun Sirih (Piper betle L) Dari Desa Luhu Kecamatan Huamual Kabupaten Seram Bagian Barat Alice M CL Luhulima; Aulia Debby Pelu; Jahra Palembang
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 2 No. 2 (2020): Juli : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v2i2.156

Abstract

The rise of disease outbreaks caused by microorganisms such as SARS, bird flu, HIV and COVID-19 has made people use products that contain antiseptics such as soap and hand sanitizer. However, if used continuously it will dissolve the layer of fat and sebum on the skin so that the skin becomes sensitive, dry, and irritated. The development of antiseptic products can be done with natural ingredients such as green betel leaf extract (Piper betle L). It is known that green betel leaf (Piper betle L) has long been used in traditional medicine and can be a natural antiseptic ingredient for making hand sanitizer. This study aims to determine the formulation of hand sanitizer from betel leaf extract (Piper betle L) accompanied by a physical stability test. The materials used in this study were methyl paraben, triethanolamine (TEA), glycerin, aquadest, 95% ethanol, lime juice, green betel leaf extract obtained from the reflux extraction process. The research was conducted by varying the betel leaf extract 55%, 60%, 65%, 70%, 75%. Tests were carried out by covering organoleptic observations (shape, color, odor), pH, homogeneity, dispersion.
Skrining Fitokimia Dan Uji Aktivitas Ekstrak Etanol Biji Labu Kuning (Curcubita Moschata) Terhadap Daya Hambat Bakteri Staphylococcus Aureus Ira P. Ely; Aulia Debby Pelu; Lukman La Bassy
JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA Vol. 2 No. 2 (2020): Juli : Jurnal Fisioterapi dan Ilmu Kesehatan Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jufdikes.v2i2.157

Abstract

Pumpkin (Cucurbita moschata) is an important vegetable because of its nutritional value and health benefits. This plant is a rich source of carotenoids, which are rich in water-soluble vitamins, phenolics, flavonoid polysaccharides, mineral salts, and vitamins, all of which are beneficial for health. Pumpkin fruit has a very thick and hard skin, so it can act as a barrier to the rate of respiration, the release of water through the evaporation process, and the entry of air that causes the oxidation process. The purpose of this study was to determine the antibacterial activity of pumpkin seed extract (curcubita moschata). ) against the inhibition of staphylococcus aureus bacteria by well diffusion method. This type of research is a true experimental laboratory using the well diffusion method. The ethanol extract of pumpkin seeds (curcubita moschata) which was tested using the well method was then divided into several concentrations including 10%, 15%, 20%, and 25%. On the NA media that has been made then smeared with Staphylococcus aureus bacteria which had been previously sterilized, then four wells were made in a petri dish after which pumpkin seed extract was added to each concentration. Chloramphenicol was used as a positive control as a positive control. It was then incubated at 37o for 24 hours, then the inhibition zone formed was then measured. The result of this research is pumpkin seed extract (curcubita moschata) has antibacterial activity in the presence of inhibition around the wells of each extract concentration. At a concentration of 10% extract with an inhibitory diameter of 19 mm, a concentration of 15% in an inhibitory diameter of 20 mm, a concentration of 20% in an inhibitory diameter of 21 mm and for a concentration of 15% with an inhibitory diameter of 24 mm, it can be concluded that the extract of pumpkin seeds (curcubita) moschata.) has antibacterial activity against Staphylococcus aureus.
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL DAUN AWAR-AWAR ( Ficus Septica Burm) KECAMATAN KAIRATU DENGAN METODE DPPH Risman Tunny; Aulia Debby Pelu; Nena Budiman
Jurnal Sains dan Kesehatan Vol. 4 No. 1 (2020): Juni : Jurnal Sains dan Kesehatan (JUSIKA)
Publisher : Universitas Muhamadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1129.959 KB) | DOI: 10.57214/jusika.v4i1.131

Abstract

Masyarakat kecematan kairatu biasa menggunakan daun sirih popar (ficus septica burm) sebagai obat luka, penyakit kulit, mengatasi bisul. Masyarakat maluku belum mengetahui kandungan dan manfaat lain dari tanaman awar-awar /sirih popar. Tujuan dari penelitian ini adalah untuk melihatkan duangan senyawa fitokimia serta melihat aktivitas antioksidan pada sampel. Menggunakan metode DPPH dan di ukur pada spektrofotometri UV-Vis. Hasil skrining fitokimia menunjukan daun awar-awar positif mengandung senyawa fitokimia vlavonoid, fenol, saponin, tanin. Hasil pengukuran dari spektrofotometri UV-Vis aktivitas antioksidan dengan metode DPPH menunjukan bahwa, pada Ekstrak methanol daun awar-awar mempunyai aktivitas antioksidan yang kuat dengan nilai IC50 sebesar (56,169 ppm), sedangkan aktivitas antioksidan vitamin C sangat kuat dari pada ekstrak methanol daun awar-awar dengan nilai IC50 (25,437ppm).
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KUMIS KUCING ( Orthosipon Aristatus )TERHADAP PERTUMBUHAN BAKTERI Staphyloccocus aureus DENGAN MENGGUNAKAN METODE DIFUSI Aulia Debby Pelu; Cut Bidara Panita Umar; Nadhira Fahreza Patimahu
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Ekonomi Trianandra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (137.5 KB) | DOI: 10.55606/klinik.v1i2.1176

Abstract

Cat's whiskers leaf plant (Ortosiphon aristatues.) is one of the plants that is efficacious as a medicinal plant. The part of the cat's whiskers leaf plant is used, namely the leaves that contain saponin compounds, flavonoids, alkaloids and tannins. The purpose of this study was to determine the most effective inhibition produced by the ethanol extract of the leaves of the cat's whiskers (Ortosiphon aristatues.) against the growth of Staphyloccocus aureus bacteria. The benefit of this research is to increase knowledge about the antimicrobial potential of ethanol extract of cat whiskers (Ortosiphon arietatus) leaves against the growth of Staphyloccocus aureus bacteria. This research method uses the diffusion method for wells. The sample used was cat whiskers leaf extract with pure strain of Staphyloccocus aureus. Treatment with cat whiskers leaf extract, the results of the test of the inhibitory activity of the cat whiskers leaf extract showed an average difference at a concentration of 65% with a diameter of 22 mm, a concentration of 70% with a diameter of 25 mm, and a concentration of 75% with a diameter of 30 mm. Ethanol extract of cat whiskers leaves with a concentration of 65%, 70%, and 75% effectiveness in inhibiting the growth of Staphylococcus aureus bacteria. Based on observations, it was shown that the ethanolic extract of Kumis Kucing leaves gave the most effective inhibitory concentration at a concentration of 75% against Staphyloccocus aureus bacteria. with a diameter of 30 mm
Uji Farmakologi Antiinflamasi Ekstrak Etanol Daun Waru Laut (Thespesia Populnea (L.) Soland) Pada Tikus Putih (Rattus Norvegicus) Pia Batmomolin; Aulia Debby Pelu; Astin Buton
Jurnal Pengabdian Ilmu Kesehatan Vol. 2 No. 2 (2022): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Politeknik Pratama Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v2i2.1276

Abstract

Waru laut (Thespesia populnea (L.) Soland) merupakan tanaman tepi pantai yang digunakan secara tradisional sebagai penurun bengkak. Tujuan dari penelitian ini adalah untuk mengetahui senyawa metabolit sekunder daun waru laut (Thespesia populnea (L.) Soland), untuk mengetahui potensi antiinflamasi ekstrak daun waru laut (Thespesia populnea (L.) Soland), dan efek dosis ekstrak daun waru laut (Thespesia populnea (L.) Soland) yang paling baik. Metode yang digunakan adalah eksperimental laboratorium dengan jenis postest control group design. Pada penelitian ini terdapat 5 kelompok hewan uji tikus putih diantaranya kelompok kontrol negatif (aquades), kontrol positif (Methylprednisolone), pelakuan 1 (ekstrak dosis 500 mg/kgBB), perlakuan 2 (ekstrak dosis 750 mg/kgBB), dan perlakuan 3 (ekstrak dosis 1000 mg/kgBB). Hasil dari penelitian ini adalah daun waru laut mengandung senyawa flavonoid, saponin, tanin. Kelompok Perlakuan 1 dan perlakuan 2 terjadi penurunan edema pada menit ke-120 yaitu 2,8 mm dari besar edema setelah 30 menit injeksi karagenin adalah pada kelompok perlakuan 1 sebesar 3,9 mm dan perlakuan 2 sebesar 3,7 mm. Sedangkan pada perlakuan 3 terjadi penurunan edema pada menit ke-120 yaitu 2,3 mm dari 3,95 mm edema setelah 30 menit injeksi karagenin. Pada dosis ekstrak daun waru laut memiliki potensi sebagai antiinflamasi dengan dosis yang paling baik adalah dosis 1000 mg/kgBB.
FORMULASI DAN EVALUASI SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) DENGAN BASIS Na-CMC DAN CARBOPOL Aulia Debby Pelu; Jayanti Djarami; Irma Yanty Larajasi
Jurnal Pengabdian Ilmu Kesehatan Vol. 2 No. 1 (2022): Maret: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Politeknik Pratama Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v2i1.1309

Abstract

Moringa leaves (Moringa oleifera L.) contain flavonoid compounds, alkaloids, saponins, and tannins which are used as quality parameters of antioxidant preparations. Peel-off facial masks have several benefits, including being able to clean dirt on the face while removing dead skin cells, preventing skin damage caused by exposure to free radicals, such as acne and black spots, removing fine wrinkles due to premature aging, and moisturizing and nourishing the skin. The purpose of this study was to identify the chemical content of Moringa leaf (Moringa oleifera L.) and to formulate and evaluate the peel-off gel mask of the ethanol extract of Moringa leaf (Moringa oleifera L.) which was good and stable using a comparison of Na-CMC and Carbopol bases. . This research method is experimental which was carried out using Na-CMC base: Carbopol from three different formulations with a concentration ratio of F1 (3%: 0.1 %), F2 (4%: 1%), F3 (5%: 1.5 %), each formulation contains 3% Moringa leaf extract (Moringa oleifera L.). Evaluation of the peel-off gel mask preparation was carried out after 2 weeks of storage. The results showed an evaluation test of the peel-off gel mask preparation of Moringa leaf ethanol extract using Na-CMC and Carbopol bases on the homogeneity test of all homogeneous concentrations, the pH test showed that all concentrations of the preparation met the pH requirements, which ranged from 5-6, on the irritation test all the preparation did not cause redness and in the dry time test all preparations met the requirements, namely under 30 minutes. The conclusion of Moringa leaf ethanol extract using Na-CMC and Carbopol bases shows that it can be used as an alternative to cosmetics and can be used as a reference for use as natural cosmetics.
UJI AKTIVITAS ANTIFUNGI EKSTRAK ANGGUR LAUT (Caulerpa sp.) ASAL PULAU GESER KABUPATEN SERAM BAGIAN TIMUR TERHADAP FUNGI Candida albicans Aulia Debby Pelu; Maryam Lihi; Moh. Nurul Iman Wokas
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 2 No. 2 (2022): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Amik Veteran Porwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v2i2.1177

Abstract

Sea Grape (Caulerpa sp.) is a group of seaweed which is a macroalgae belonging to the Caulerpaceae family . Sea Grape very potential as a new antifungal drug because it contains secondary metabolites of saponins and flavonoids that can inhibit the growth of the fungus Candida albicans . The purpose of this study was to determine the content of secondary metabolites present in sea grapes and antifungal activity test of sea grapes (Caulerpa sp.) which was extracted using 70% ethanol as a solvent against the fungus Candida albicans. The antifungal activity was tested using the disc diffusion method with several concentrations of 5%, 10%, 25%, 50%, 85, 130%, 185%, and 250%, ketoconazole as a positive control and aquadest as a negative control. The results showed that the extraction of sea grapes contains secondary metabolites, namely: Saponins, Flavonoids, Tannins and Steroids capable of inhibiting the growth of the fungus Candida albicans, at a concentration of 25% with an inhibition zone diameter of 12.5 mm, 50% diameter of the inhibition zone 14.5 mm, 130% the diameter of the inhibition zone is 17.5 mm, 185% the diameter of the inhibition zone is 19 mm and 250% with the diameter of the inhibition zone is 22mm. The test results showed that the effective and very strong concentration of inhibiting the growth of Candida albicans was at a concentration of 250% with an inhibition zone of 22 mm.
Co-Authors Alice M CL Luhulima Astin Buton Cut Bidara Panita Umar Dwi Sintya Karubaba Ira P. Ely Irma Yanty Larajasi Jahra Palembang Jayanti Djarami Jayanti Djarami Lukman La Bassy Maryam Lihi Moh. Nurul Iman Wokas Nadhira Fahreza Patimahu Nena Budiman Pia Batmomolin Risman Tunny Sardila Bugis