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All Journal Science Midwifery Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan JPS (Jurnal Pharma Saintika)
Mevy Trisna
Akademi Farmasi Dwi Farma Bukittinggi
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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The Test Effect of Glucose Tolerance of Green Apple (Mallus sylvestris Mill.) Juice on Male White Mice Mevy Trisna; Renatalia Fika; Dewi Novita; Budi Setiawan; Wenni
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.967

Abstract

Diabetes Mellitus or diabetes is a disease characterized by an increase in blood sugar levels beyond normal limits due to disruption of carbohydrate metabolism due to a deficiency of the insulin hormone caused by impaired pancreatic function. Glucose tolerance is disturbed when a person's blood sugar level on the glucose tolerance test is above normal but not high enough. Green Apple (Mallus sylvestris Mill.) Glucose Tolerance Test. Against White Male Mice orally by measuring mice's blood sugar levels every 30 minutes for 3 hours at a dose of 1.12 g; 2.24 g; and 4.48 g. The study's results using the oral glucose tolerance test method showed that the glucose tolerance effect of green apple juice at a dose of 1.12 g averaged blood sugar levels from 160.33 mg/dl to 89.33 mg/dl, at a dose of 2.24 g. – average blood sugar level from 204.67 mg/dl to 122.33 mg/dl and a dose of 4.48 g average blood sugar level from 329.67 mg/dl to 175.00 mg/dl. At a dose of 4.48 g, it can provide a faster effect on lowering the glucose levels of the test animals from statistical testing utilizing the T-test obtained tcount ≤ ttable means that there is no significant difference between the test substance group and the normal group.
Evaluation of the Rationality of OTC (Over The Counter) Drug Self-Medication in Patients in Pasaman Barat District Pharmacy Budi Setiawan; Renatalia Fika; Mevy Trisna; Nurhida Yanti
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.1023

Abstract

Self-medication is simply a person's attempt to treat symptoms of illness or disease without consulting a doctor first. Self-medication also means treating all complaints about oneself with medicines purchased directly at pharmacies or drug stores on their initiative without a doctor's prescription. OTC (Over The Counter) drugs are medicines that can be purchased without a prescription, namely over-the-counter and limited over-the-counter drugs, including fever-reducing drugs, pain relievers and inflammation relievers, cough medicines, cold medicines, ulcer medicines, diarrhea medicines, and skin medicines. The use of drugs in self-medication is carried out correctly to ensure the accuracy, rationality, and safety of drug use in self-medication. This study aimed to determine the demographic data characteristics of self-medication patients, the rationality of self-medication, and the influence of patient demographic data characteristics on rationality in OTC (Over Counter) drug self-medication patients. This study used a cross-sectional method. As many as 100 respondents aged 18-60 who self-medicated OTC (Over Counter) drugs at the West Pasaman District Pharmacy were involved in this study. Data collection was carried out using a questionnaire. Data were analyzed using Statistical Product And Servicer Solution (SPSS) 23. The results of this study showed that the majority of respondents who self-medicated OTC (Over Counter) drugs were 58% women, 63% of the age group 18-60 years, the last education group was low ( SD, SMP, SMA) by 77% and the non-PNS/non-private employee group is 82%. Respondents who used self-medication rationally were quite large, namely 86%. The factor that influences self-medication is age. While gender, education, and occupation do not affect self-medication
KEBO LEAF ETHANOL EXTRACT (Euphorbia hirta L.) ANTI-INFLAMMATORY EFFECTS IN FEMALE WHITE RATS DETERMINED USING ARTIFICIAL UDEMA METHOD Mevy Trisna; Renatalia Fika; Budi Setiawan; Rini Wulandari
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Ekonomi Trianandra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (898.552 KB) | DOI: 10.55606/klinik.v1i2.683

Abstract

An ordinary protective reaction to tissue damage brought on by physical trauma, chemical agents, or harmful microbiological agents is inflammation. The kebo excerpt plant has significant amounts of flavonoids, which have anti-inflammatory and antioxidant properties. This study used the artificial udema method to determine the anti-inflammatory effects of Kebo Petikan leaves (Euphorbia hirta L.) ethanol extract in female white rats. This study applied a subcutaneous 1% carrageenine inducer as an anti-inflammatory drug on the soles of rats' feet. Following the injection of the test material at doses of 26 mg, 52 mg, and 104 mg, a decrease in volume was the metric that was observed. The results of the study showed the anti-inflammatory effect of ethanol extract of kebo petikan leaves at a dose of 26 mg/5ml had a strength of 32.3%, a dose of 52 mg/5ml had a strength of 78.48 %, and a dose of 104 mg/5ml had a strength of 91.46% compared to drugs.
Pengaruh Efek Antipiretik Pemberian Kombinasi Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Danekstrak Etanol Daun Lengkeng (Dimocarpus Longan L.)Pada Tikus Putih Betina Oktifanny Oktifanny; Mevy trisna
Journal Pharma Saintika Vol. 5 No. 2 (2022): April : Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v5i2.10

Abstract

A study has been carried out on the effect of the antipyretic effect of giving a combination of ethanol extract of starfruit leaves (Averrhoa bilimbi L.) and ethanol extract of longan leaves (Dimocarpus longan L.) in female white rats induced by intraperitoneal 5% peptone 5 ml/head with the aim of knowing combination effect and determining the effective dose as an antipyretic.Temperature measurements were carried out for 2 hours with 30 minute intervals. Measurement results data were analyzed statistically using the ANOVA method with the one way Anova method. The data obtained are normally distributed and have a homogeneous variant. With Fcount ≤ Ftable where there is no significant difference between Paracetamol and the test solution. It can be concluded that the ethanol extract of starfruit leaves (Averrhoa bilimbi L.) and the ethanol extract of longan leaves (Dimocarpus longan L.) are efficacious as antipyretics at doses (25+20) mg/200 g BW, doses (50+40) mg/200 g BW and dose (100+80) mg/200 g BW and the percentage of effect strength against paracetamol was obtained respectively 61.1%, 77.3%, 86.4%.
Co-Authors Budi Setiawan Dewi Novita Nurhida Yanti Oktifanny Oktifanny Renatalia Fika Rini Wulandari Wenni