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All Journal Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Rini Wulandari
Akademi Farmasi Dwi Farma Bukittinggi
Health Professions Medicine & Pharmacology Public Health

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KEBO LEAF ETHANOL EXTRACT (Euphorbia hirta L.) ANTI-INFLAMMATORY EFFECTS IN FEMALE WHITE RATS DETERMINED USING ARTIFICIAL UDEMA METHOD Mevy Trisna; Renatalia Fika; Budi Setiawan; Rini Wulandari
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Ekonomi Trianandra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (898.552 KB) | DOI: 10.55606/klinik.v1i2.683

Abstract

An ordinary protective reaction to tissue damage brought on by physical trauma, chemical agents, or harmful microbiological agents is inflammation. The kebo excerpt plant has significant amounts of flavonoids, which have anti-inflammatory and antioxidant properties. This study used the artificial udema method to determine the anti-inflammatory effects of Kebo Petikan leaves (Euphorbia hirta L.) ethanol extract in female white rats. This study applied a subcutaneous 1% carrageenine inducer as an anti-inflammatory drug on the soles of rats' feet. Following the injection of the test material at doses of 26 mg, 52 mg, and 104 mg, a decrease in volume was the metric that was observed. The results of the study showed the anti-inflammatory effect of ethanol extract of kebo petikan leaves at a dose of 26 mg/5ml had a strength of 32.3%, a dose of 52 mg/5ml had a strength of 78.48 %, and a dose of 104 mg/5ml had a strength of 91.46% compared to drugs.
Co-Authors Budi Setiawan Mevy Trisna Renatalia Fika