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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal of Pharmaceutical Care and Sciences
Hansel Hens Tangkas
Universitas Sari Mulia
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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Analisis Rhodamin B Dalam Lipstick Di Kecamatan Banjarmasin Utara Hansel Hens Tangkas; Trias S. Putri; Syarifah S. Aisyah; Hairunnisa Hairunnisa; Helda Oktavia; Indah Purnamasari; Siti Salbiah; Rahmadani Rahmadani
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i2.190

Abstract

Background: Rhodamine B is a synthetic substance which is generally used as a dye in paper, textile or ink which causes respiratory irritation and when used can cause cancer and liver damage in the body. The use of Rhodamine B for a long time will cause acute danger if swallowed and cause vomiting which causes irritation of the digestive tract and causes symptoms of poisoning. The purpose of this study was to determine the presence of lipstick containing Rhodamine B. The testing method carried out used for qualitative testing is Thin Layer Chromatography (TLC) and quantitative testing using UV-VIS Spectrophotometry. The results of the lipstick sample were qualitatively proven to contain rhodamine B with a mobile phase and a stationary phase of 70% ethanol: ammonia: ethyl acetate (5:2,5:12,5) and silica gel 254 nm. With an RF value of 0.57. In quantitative testing, rhodamine B levels were found to be 2.598 mg/L. Conclusion lipsticks circulating in the East Banjarmasin sub-district are proven to contain rhodamine B.
KAJIAN DAMPAK EFEK SAMPING PENGGUNAAN OBAT OFF LABEL PADA PASIEN SISTEMIK LUPUS ERITEMATOSUS (SLE) TERHADAP BIAYA KESEHATAN Iwan Yuwindry; Yusri Yusri; Hansel Hens Tangkas
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1313

Abstract

The main problem in conducting lupus treatment is that most drugs for the therapy provided have not been authorized so that they are still included in the class of off-label drugs for the treatment of lupus. The purpose of this study was only to see the impact of side effects of off-label drugs on health costs. This study was conducted using a cross-sectional method by means of a survey using the Naranjo Algorithm instrument (PESO Book) to determine the level of incidence of side effects that exist in LSE therapy using off-label drugs and calculate the health costs of lupus patients. The results showed that the most respondents were in adulthood (19 respondents  47.5%), then the most respondents were female (37 respondents or 92.5%). Data on the incidence of side effects obtained the most respondents in the Probable category (most likely to occur ROM) of 14 respondents or 35%. In addition, data on health costs incurred by more respondents experienced an increase, namely 23 respondents or 57.5%. The research data shows the calculated r value is 0.3044 and the Sig (2-tailed) value is 0.000 with a confidence level (CI) of 0.05. The results of the analysis clearly show that there is a significant relationship between the side effects of using off-label drugs on the health costs of lupus patients, where if the value of side effects experienced by respondents is high, the value of respondents' health costs is also high.
Co-Authors Hairunnisa Hairunnisa Helda Oktavia Indah Purnamasari Iwan Yuwindry Rahmadani Rahmadani Siti Salbiah Syarifah S. Aisyah Trias S. Putri Yusri Yusri