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All Journal KESANS : International Journal of Health and Science
Nanda Dhea Ayu Sawitri
Universitas Muhammadiyah Surakarta
Chemistry Health Professions Medicine & Pharmacology Physics Public Health

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Potential Anti-Bacterial Extract of Red Belt (Piper Crocatum Ruiz & Pav.) Against Staphylococcus Epidermidis Nanda Dhea Ayu Sawitri; Iin Novita Nurhidayati Mahmuda
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 11 (2022): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i11.102

Abstract

Introduction: Red betel leaf is a plant native to Indonesia which is used as an antiseptic, anti-cancer, and infection treatment. The ethanol content of red betel leaf extract is known to have antibacterial activity. Among them there are alkaloids, flavonoids, essential oils, tannins, and saponins. Objective: to determine the potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) in inhibiting the growth of Staphylococcus epidermidis bacteria. Methods: Staphylococcus epidermidis bacteria were divided into 5 groups, PEG 5% as negative control, clindamycin 30µg/disk as positive control, extract 20%, 40%, 80% as treatment group. Measuring the zone of inhibition using a ruler. Result and Discussion: Staphylococcus epidermidis inhibition zone was formed at concentrations of 20%, 40%, 80%. Kruskal Wallis analysis showed significant results of p = 0.000 for bacteria. Conclusion: Red betel leaf extract (Piper crocatum Ruiz & Pav.) has significant antibacterial activity against Staphylococcus epidermidis. The higher the concentration, the larger the diameter of the inhibition zone.
Co-Authors Iin Novita Nurmahmudah, Iin Novita