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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin
Marsudi Hutomo, Marsudi
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Immunology & microbiology Public Health

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Dermoscopy Supports the Diagnose of Papulosquamous Disorders Alinda, Medhi Denisa; Hutomo, Marsudi; Setyaningrum, Trisniartami
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.201 KB) | DOI: 10.20473/bikkk.V26.3.2014.1-7

Abstract

Background: The diagnose of papulosquamous skin disorder was established by clinical symptoms. However, some of papulosquamous manifestation are alike with each other and lead to misdiagnostic. Histopathology examination usually can help to establish diagnose but this method is invasive and time consuming. Purpose: To evaluate dermoscopic features of papulosquamous disorder. Methods: Descriptive observasional cross sectional study, total sampling in ward and out patient clinic of Dermato-venereology Department Dr. Soetomo General Hospital. Twenty four samples were included in the study, followed by the procedures from anamnesis, physical examination, dermoscopy procedures, and histopathology examination. Results: From 24 samples, 19 samples showed plaque psoriasis describing 12 ring patterns, 1 cluster pattern, 2 patchy patterns, 2 reguler patterns, and 2 unspesific patterns; 3 samples showed nummular dermatitis describing 2 cluster patterns and 1 unspesific pattern; and 2 samples showed pityriasis rosea describing 2 pheripery patterns. Conclusion: Dermoscopy can support the diagnosis of papulosquamous skin disorder especially plaque psoriasis.Key words: papulosquamous disorder, dermosocopy, histopathology examination, plaque psoriasis.
Salivary Cortisol Levels Representing Serum Cortisol Levels in Atopic Dermatitis Patients Adisty, Novia Indriyani; Hutomo, Marsudi; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.193 KB) | DOI: 10.20473/bikkk.V27.3.2015.170-175

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder, recurrent lesion with a distinctive and specific distribution of lesions according phases. Patients with allergic diseases have been known to have a variety of patterns of cortisol. Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis and the role of cortisol has been studied in patients with DA. Free cortisol adrenal cortex is considered biologically active, which passively diffuses into all body fluids including saliva. Another advantage is the saliva examination is non-invasive, stress free and easy to do anywhere. Purpose: To analyze the correlation between levels of serum cortisol and salivary cortisol in patients with AD. Methods: Analytical, observational, cross-sectional study of the 29 AD patients who underwent blood and saliva samples by the method of "passive drooling" conducted on the hour 8:00 to 9:00 to see the levels of serum cortisol and salivary cortisol. Results: Twenty-nine subjects revealed mean serum cortisol levels 6,703,82g/dL, mean salivary cortisol levels was 1,430,96g/dL. Equation of salivary cortisol = 0,471+0,142*serum cortisol 2 (R=28,5%). Conclusions: The increasing of serum cortisol level of AD patients will result in increased levels of cortisol in saliva. Saliva collection methods by “passive drooling” were able to describe the serum cortisol levels at 28,5%.Key words: atopic dermatitis, serum cortisol, salivary cortisol.
Co-Authors Diah Mira Indramaya Medhi Denisa Alinda, Medhi Denisa Novia Indriyani Adisty, Novia Indriyani Trisniartami Setyaningrum