Irma Tarida Listiyawati, Irma Tarida
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Oral Corticosteroid Therapy in Leprosys new patients with Type 2 Reaction Listiyawati, Irma Tarida; Sawitri, Sawitri; Agusni, Indropo; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (134.721 KB) | DOI: 10.20473/bikkk.V27.1.2015.48-54

Abstract

Background: Leprosy type 2 reactions is an acute inflammatory episode in lepromatous leprosy patient that ascociated with deposition of immune complexes. Standard regiment for severe reaction is corticosteroid. Almost Leprosy type 2 reactions patients become chronic and recurrent so it implicates to more complications if it was not managed well. Purpose: To determine the distribution of type 2 reactions patients which treated with oral corticosteroid in leprosy division of dermatovenereology outpatient clinic of Dr. Soetomo General Hospital. Methods: Retrospective study using new patients medical record during the period of January 1 2009 until December 31 2013 and the observation continued until December 31 2013. Results: The total type 2 reactions patients with oral corticosteroid was 112 patients, mostly were male aged between 25-64 years and has the Lepromatous Leprosy (LL) type (33%), the reactions happened after RFT  (43.8%), 65.2% had metil prednisolon medication, the initial equivalent dose was 30 mg in 32.1% patient. 21.4% patient had more than one cycle  of corticosteroid therapy and 8.9% patient had the steroid side effect. Conclusion: Leprosys type 2 reactions tend to be chronic and recurrent and the impact were patients got longterm continuously corticosteroid medication, so the patients need to be monitored including side effects.Key words: leprosys type 2 reaction, oral corticosteroid, side effects.