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Erda E. Rame Hau
Program Studi Kesehatan Hewan, Jurusan Peternakan, Politeknik Pertanian Negeri Kupang,

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KARAKTERISTIK DAN PENGGUNAAN LIPOPOLISAKARIDA (LPS) BRUCELLA DALAM MEDIK VETERINER Eni Rohyati; Erda E. Rame Hau; Noviani N. Toelle; Gerson Y. I. Sakan
Partner Vol 27, No 2 (2022): Edisi November 2022
Publisher : Politeknik Pertanian Negeri Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35726/jp.v27i2.1058

Abstract

Lipopolysaccharide (LPS) is a major component of cell membranes with gram negative bacteria including Brucella. The stain of B.abortus, B.melitensis, and B.suiscan be rough or smooth strains and express rough LPS (R-LPS)) or smooth LPS (S-LPS) as the main surface antigen; while, B .ovis and B.canis are two natural rough species that express R-LPS as the main antigen. R-LPS in B.abortus RB51 which is a stable R-LPS mutated from 2308 virulent S strains, while S-LPS is produced from B.abortus S1119-3 or S99 which is extracted by heating and then cooled. Both types of LPS can stimulate the humoral and innate immunity host immunity response. Those types are used as antigens in the diagnostic device and as immunogens of vaccines.  Keyword; LPS bakteri, Brucella, Medik Veteriner