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All Journal Manuju : Malahayati Nursing Journal Jurnal Farmasi dan Sains Indonesia (JFSI)
Debby Juliadi
Universitas Mahasaraswati
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Skrining Fitokimia, Formulasi dan Antioksidan Sediaan Granul Effervescent Ekstrak N-Butanol Buah Dewandaru (Eugenia uniflora L.) Puguh Santoso; Debby Juliadi; Ni Nyoman Wahyu Udayani; I Putu Pasek Jaya Separsa; Ida Ayu Gede Syntya Mahayani; I Gede Yodhi Trismawan
Malahayati Nursing Journal Vol 5, No 2 (2023): Volume 5 Nomor 2 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i2.7509

Abstract

ABSTRAK Kandungan metabolit sekunder tanaman yang berkhasiat obat sebagai acuan pemanfaatan untuk membuat sebuah produk, Dewandaru (Eugenia uniflora L), merupakan salah satu tanaman daerah tropis yang belum banyak di gali dan di manfaatkan secara ilmiah. Tujuan penelitian ini  mengetahui metabolit sekunder, uji mutu fisik sediaan effervescent dan uji antioksidan ekstrak buah buah Dewandaru. Metode penelitian eksperimenal ini menujukkan bahwa hasil metabolit sekunder ekstrak n- butanol buah Dewandaru menunjukkan adanya senyawa alkaloid, tannin, flavonoid, dan saponin, hasil uji mutu fisik sdiaan effervescent menunjukkan mutu fisik yang baik di semua jenis pengujian, Pada pengujian pH, sediaan memiliki pH 6. Dari hasil penelitian yang telah dilakukan maka dapat disimpulkan bahwa sediaan granul effervescent memiliki mutu fisik yang baik, uji antioksidan formula effervescent mendapatkan hasil 21,196 ppm.  Termasuk antiosidan yang sangat kuat. Kata Kunci: Antioksidan, Efervescent, Mutu Fisik, Skrining  ABSTRACT The content of secondary metabolites of plants that have medicinal properties as a reference for use to make a product, Dewandaru (Eugenia uniflora L), is one of the tropical plants that has not been widely explored and used scientifically. The purpose of this study was to determine secondary metabolites, test the physical quality of effervescent preparations and test the antioxidants of Dewandaru fruit extracts. This experimental research method showed that the results of secondary metabolites of the n-butanol extract of Dewandaru fruit showed the presence of alkaloids, tannins, flavonoids, and saponins, the results of the physical quality test of effervescent preparations showed good physical quality in all types of tests. 5. From the results of the research that has been done, it can be concluded that the effervescent granule preparation has good physical quality, the antioxidant test of the effervescent formula obtained 21.196 ppm results. Including very strong antioxidants. Keywords: Antioxidant, Effervescent, Physical Quality, Screening
Faktor Penyebab Perilaku Penjualan dan Pembelian Antibiotik Tanpa Resep Dokter Novita Dewi; Debby Juliadi
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p19-25

Abstract

Pharmacies are the main source of getting antibiotics. Access to antibiotics without a prescription at pharmacies is common in many countries, including Indonesia. The sale of antibiotics without a prescription in pharmacies has become a global problem, especially in developing countries. However, the dominant factor that causes the behavior of selling antibiotics without a prescription in Indonesian pharmacies is not known with certainty. The purpose of this article is to find out the dominant factors that influence the behavior of selling and using antibiotics without a doctor's prescription in pharmacies. The method used is by conducting library searches on search sites such as Google Schler with the keywords "antibiotics without a prescription, patient behavior, pharmacists, pharmacies". Where the results are factors that influence sales behavior and use of antibiotics without a doctor's prescription, namely the ease of access to antibiotics and cost savings factors, patient attitudes and recommendations from friends/relatives.
Gambaran Penggunaan Vitamin C Sebagai Imunomodulator Pada Pasien Dewasa Dengan Covid-19: Studi Literatur Luh Tuti Suryati; Debby Juliadi
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p31-40

Abstract

Corona virus or COVID 19 is a virus that causes disease in animals or humans. COVID-19 more often attacks the respiratory tract. Improving the immunity of COVID-19 patients is very much needed because the treatment for COVID-19 has not been found. Vitamin C is a vitamin that can prevent and treat respiratory infections by enhancing various immune cell functions. Vitamin C acts as a powerful antioxidant and helps replace damaged cells so it can help with COVID-19. This literature study aims to determine the use of vitamin C as an immunomodulator in adult COVID-19 patients. The data collection method was obtained by reviewing 10 journals using Google Scholar and Pubmed using English-language journals. The keywords used are vitamin C, COVID-19, treatment. The results obtained in the form of intravenous vitamin C with a dose of can improve the lives of COVID-19 patients by increasing the immunity of infected patients. This can be seen from the inhibition of the development of cytokines and an increase in lymphocytes and CD4+ T cells. In addition, it improves the patient's respiratory function with an increase in PiO2/FiO2.
Co-Authors I Gede Yodhi Trismawan I Putu Pasek Jaya Separsa Ida Ayu Gede Syntya Mahayani Luh Tuti Suryati Ni Nyoman Wahyu Udayani Novita Dewi Puguh Santoso