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All Journal Widya Warta Krida Rakyat Jurnal Biologi dan Pembelajarannya (JBP) Pharmed: Journal of Pharmaceutical Science and Medical Research JIIP (Jurnal Ilmiah Ilmu Pendidikan) Biospektrum Jurnal Biologi
Christianto Adhy Nugroho
Program Studi Biologi, Fakultas Teknologi Pertanian Universitas Katolik Widya Mandala Surabaya (Kampus Kota Madiun)
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Public Health Other

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Journal : Widya Warta

 1 
AKTIVITAS HIPOGLIKEMIK EKSTRAK ROSELA (Hibiscus sabdariffa L.) PADA TIKUS PUTIH DIABETES Adhy Nugroho, Christianto
Widya Warta No. 01 Tahun XXXIV / Januari 2010
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Rosela is one of medicinal herbs. The aim of the study was to find out the hypoglycemic effect of oral intake of Rosela extract on diabetic white rat. This research apllied Complete Randomized Design of four groups with five replications to each. The treatment for those groups was: no treatment, insulin 5 unit/kg body weight, 250 mg/kg body weight of Rosela extract, and 500 mg/kg body weight of Rosela extract. The parameters used were fasting blood glucose concentration and blood glucose concentrations at the 60th and 120th minutes. The result showed that the extract of Rosela decreased blood glucose concentration. The treatment with Rosela extract 250 mg decreased blood glucose concentrations as much as 24,32%, while  that with Rosela extract 500 mg decreased blood glucose concentration as much as 32,44%.
Pengaruh Ekstrak Rosela (Hibiscus Sabdariffa) terhadap Kadar Trigliserida Tikus Putih Diabetes Adhy Nugroho, Christianto
Widya Warta No. 02 Tahun XXXVII /Juli 2013
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Rosela is one of medicinal herbs. Rosela contents phytochemicals such as: gossypetine, hibiscin, flavonoid phenol, anthocyanin. The aim of the study was to find out the effect of oral intake of Rosela extract on triglyceride concentration of diabetic white rat. This research applied Experimental Method which concists of four groups with five replications to each. The treatment for each of those groups was: (1) normal rat without treatment, (2) diabetic rat without treatment of Rosela extract, (3) diabetic rat treated 250 mg/kg body weight of   Rosela extract, (4) diabetic rat   treated   500 mg/kg body weight of Rosela extract. The parameters used were triglyceride concentration. The result showed that the extract of Rosela reduced triglyceride concentration.  
DAYA ANTIPIRETIK EKSTRAK ROSELA (Hibiscus Sabdariffa) Adhy Nugroho, Christianto
Widya Warta No. 01 Tahun XL/Januari 2016
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Rosela is one of the medicinal plants, which contain active compounds of flavonoid. The research was conducted to  determine the antipyretic power of Rosela. This study is a laboratory experiment with mice as test animals. The mice were divided into 3 groups and 4 replications. Group I was the control, without treatment. Groups II and III applied Rosela extract, each of which was 250 mg/kg BW and 500 mg/kg BW. The fever of the mice was induced using DPT vaccine. Rectal temperature was measured every 3 hours for 24 hours.  The results revealed that Rosela extract possesses antipyretic ability.
AKTIVITAS HIPOKOLESTEROLIMIK EKSTRAK ROSELA (Hibiscus sabdariffa) PADA TIKUS PUTIH DIABETES Adhy Nugroho, Christianto
Widya Warta No. 01 Tahun XXXVI / Januari 2012
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Rosela is one of medicinal herbs. The aim of the study was to find out the hypocholesterolimic effect of oral intake of Rosela extract on diabetic white rat.This research applied Complete Randomized Design of four groups with five replications to each. The treatment for those groups was: no treatment, metformin 9 mg/200 g body weight, 250 mg/kg body weight of Rosela extract, and 500 mg/kg body weight of Rosela extract. The parameters used were cholesterol concentration before and after the treatment.The result showed that the extract of Rosela reduced cholesterol concentration.
PENGARUH PEMBERIAN JUS KULIT MANGGIS TERHADAP KADAR LOW DENSITY LIPOPROTEIN (LDL) DAN HIGH DENSITY LIPOPROTEIN (HDL) MENCIT Adhy Nugroho, Christianto
Widya Warta No. 01 Tahun XLII/Januari 2018
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

High level of fat in the body can cause various diseases. To reduce the fat content people made various attempts, for example, by having diet, doing regular excercise, or taking medicine. Plants are source of chemicals that are the basic ingredients of drugs. This research, therefore, was aimed to determine the effect of mangosteen peel juice on low density lipoprotein (LDL) and high density lipoprotein (HDL). Materials used for the research were mangosteen peels and animals test. The experiment was conducted by using an experimental method consisting of 4 treatments and 5 replications. Group 1 had no treatment, group 2 was given quail egg yolk, group 3 was given quail egg yolks and 200 g mangosteen peel juice, group 4 was given quail egg yolk and mangosteen juice of 300 g  of mangosteen peel juice. The treatment was carried out for 14 days. The results showed that the LDL levelwas decreased while the HDL level increased.
KADAR TRIGLISERIDA MENCIT SETELAH PEMBERIAN AIR PERASAN DAUN KETEPENG (Cassia alata) Adhy Nugroho, Christianto
Widya Warta No. 02 Tahun XLIII/Juli 2019
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

The extraordinary development of technology makes all human needs can be afforded easily by gadgets. The exixtence of gadgets can reduce human physical activities that lead to health assault, namely dylipidemia. Increasing or decreasing fat fractions in blood vessels is one of its symptoms. One of the fat fractions is trigycerides. The ketepeng plant which contains active substance such as flavonoids, tannis, and saponine have been widely used for medical treatment. This study aimed to determine the ability of ketepeng juice in reducing triglyceride levels.In this study, the tested animals in group 1 were treated with high-fat feed, the ones in group 2 were given high-fat feed, and the ones in group 3 were given high-fat feed and ketepeng leaf juice concentration of 25% (w / v), namely 0.5 ml / 20 grams BW. The results showed that the juice of ketepeng leaves could reduce the triglyceride levels of mice.
Co-Authors Alfinda Dwi Aprillyanti Angga Rahabistara Sumadji Angga Rahabistara Sumadji Antonius Budiawan Darea Silva Moningka Endang Purwaningsih Engki Restulangi Leo Eladisa Ganjari Restulangi, Engki Yustika Aprilia Maudyana