Fitri Siska
Institut Kesehatan Medistra Lubuk Pakam

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SEMINAR OF EVALUATION OF THE USE OF CIPROFLOXACIN ANTIBIOTICS IN INFECTION PATIENTS URINARY TRACT (PUT) IN CARE INSTALLATION HOSPITAL GRANDMED LUBUK PAKAM Yanna Rotua Sihombing; Fitri Siska; Kristian Cahayani Zebua; Dina Wahyuni Nasution
JURNAL PENGMAS KESTRA (JPK) Vol 2 No 2 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.278 KB) | DOI: 10.35451/jpk.v2i2.1439

Abstract

Urinary Tract Infection (UTI) This is an infectious disease characterized by the growth and multiplication of bacteria in the urinary tract. The most common etiology in more than 80% of uncomplicated UTI cases is Escherichia coli, and less than 50%, Proteus spp, Klebsiella pneumoniae, Enterobacter spp, Pseudomonas aeruginosa, Staphylococcus, and Enterococcus. Candida species are a common cause of urinary tract infection in patients with severe chronic catheterization. The clinical forms of UTI are classified according to age, intensity of inflammatory response, and location of urinary tract infection. Children aged 2 months to 2 years with a UTI require special attention because they are likely to have atypical clinical presentations, invasive urine specimen collection, and kidney injury. This study aims to determine the dosage and composition of the antibiotic ciprofloxacin in patients with urinary tract infections at Grandmed Lubuk Pakam Hospital for the period November-December 2021. The method used is a descriptive assessment because it aims to provide an objective picture or description of the situation. Data collection was carried out retrospectively. Both research by reviewing historical information, as well as data collection by observing the medical records of urinary tract infection patients at Grandmed Lubuk Pakam Hospital in 2021
ANDALIMAN QUERCETIN (ZANTHOXYLUM ACANTHOPODIUM DC.) USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) METHOD AND ITS ANTIFUNGAL ACTIVITY AGAINST PITYROSPORUM OVALE Fitri siska; Romauli Anna Teresia Marbun; Anisa Maharani
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1857

Abstract

People today complain with dandruff accompanied by itching will cause a lack of confidence because of the unpleasant smell and reduce the beauty of the hair. Andaliman is a plant that grows a lot in the Toba Samosir area which is usually used as a spice for cooking. Examination of secondary metabolite compounds contained in these natural materials is the main thing that is important to do. In other studies, andaliman has been studied to provide antimicrobial, antioxidant, and anti-inflammatory effects. The test method is carried out using the High Performance Liquid Chromatography (HPLC) Method and the minimum inhibitory concentration test using the diffusion method in order to use paper backups with several variations in test concentration. This is related to the content of secondary metabolites such as flavonoids, terpene alkaloids, benzophenthridine alkaloids, pyranoquinoline alkaloids, quaternary isoquinoline alkaloids, aporphyrine alkaloids, essential oils and several types of lignin. Flavonoids are secondary metabolites of polyphenols found in many plants and have a variety of biological effects including antiviral, anti-inflammatory, and antioxidant. Quercetin to derivative active compounds The test results of the minimum inhibitory concentration of the extract showed an average inhibitory power of 17.26 mm at a concentration of 80% and EEAD quercetin levels with a concentration of 6.25; 12,5; 25; 50; and 100 ?g/ml contains quercetin percentages of 143.5, 242.15, 395.12, 865.2, and 1134.12 ?g/ml.