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All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Kristian Cahayani Zebua
Institut Kesehatan Medistra Lubuk Pakam
Health Professions Medicine & Pharmacology Nursing Public Health

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The EVALUATION OF THE USE OF ANTI-INFLAMMATORY DRUGSIN PATIENTS RHEUMATOID ARTHRITIS OUTPATIENT AT GRANDMED HOSPITAL LUBUK PAKAM Yanna Rotua Sihombing; Romauli Anna Teresia Marbun; Kristian Cahayani Zebua; Dayana Lestari
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1315

Abstract

Rheumatoid arthritis is an autoimmune disease characterized by inflammation of the joints that can become chronic. Rational use of drugs aims to ensure that patients get safe and effective treatment in the right time frame and at an affordable price according to their needs In the outpatient facility of Lubuk Pakam Hospital, patients experience symptoms such as pain, inflammation, morning joint stiffness and difficulty moving at appropriate doses. This study aims to aim to obtain an objective picture or picture of the situation. Data collection was carried out retrospectively, namely by observing the medical records of rheumatoid arthritis patients at Grandmed Lubuk Pakam Hospital in 2021. A total of 13 (56.5%) female patients and 10 (56.5%) (43.5%) male patients, according to the number of rheumatoid arthritis patients at the outpatient facility of GrandMed Lubuk Pakam Hospital in 2021. This makes the inclusion criteria for all anti-inflammatory agents incomplete in rheumatoid arthritis and the exclusion criteria for all medical records in rheumatoid arthritis patients. Analysis of data based on age, gender, rationality of the drug, correct indications, correct patient, correct drug, correct dosage. The Outpatient Study of GrandMed Lubuk Pakam Hospital 2021 is: Correct Indications (100%), Correct Patients (100%), Correct Drugs (100%), Correct Dosage (91.3%). The treatment of patients with rheumatoid arthritis at GrandMed Lubuk Pakam Hospital can still be said to be fully good
THE SOCIALIZATION OF RIMBANG FRUIT ACTIVITY TEST RESULTS (Solanum torvum Swartz) BY HYPERSENSITIVITY METHOD SLOW TYPE Romauli Anna Marbun; Imelda Oktaviani Br Sihombing; Kristian Cahayani Zebua
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 1 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.741 KB) | DOI: 10.35451/jpk.v2i1.1109

Abstract

Immunomodulators are compounds that improve the immune system. One of the plants that has immunomodulatory activity is Rimbang Fruit (Solanum torvum swartz). The purpose of this service is to inform the immunomodulatory effect of rimbang ethanol extract in male rats which is the result of research. Research related to immunomodulatory activity was determined using a digital plethysmograph by measuring the difference between the volume of swelling of the last leg and the volume of swelling of the first leg. The treatment group was divided into 5 groups. Each group consisted of 5 CMC-Na 0.5% mice (negative control), Imboost 25 mg/kg BB (positive control), doses of EEBR100, 200 and 400 mg/kg BB and S. aureus antigens.
SEMINAR OF EVALUATION OF THE USE OF CIPROFLOXACIN ANTIBIOTICS IN INFECTION PATIENTS URINARY TRACT (PUT) IN CARE INSTALLATION HOSPITAL GRANDMED LUBUK PAKAM Yanna Rotua Sihombing; Fitri Siska; Kristian Cahayani Zebua; Dina Wahyuni Nasution
JURNAL PENGMAS KESTRA (JPK) Vol 2 No 2 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.278 KB) | DOI: 10.35451/jpk.v2i2.1439

Abstract

Urinary Tract Infection (UTI) This is an infectious disease characterized by the growth and multiplication of bacteria in the urinary tract. The most common etiology in more than 80% of uncomplicated UTI cases is Escherichia coli, and less than 50%, Proteus spp, Klebsiella pneumoniae, Enterobacter spp, Pseudomonas aeruginosa, Staphylococcus, and Enterococcus. Candida species are a common cause of urinary tract infection in patients with severe chronic catheterization. The clinical forms of UTI are classified according to age, intensity of inflammatory response, and location of urinary tract infection. Children aged 2 months to 2 years with a UTI require special attention because they are likely to have atypical clinical presentations, invasive urine specimen collection, and kidney injury. This study aims to determine the dosage and composition of the antibiotic ciprofloxacin in patients with urinary tract infections at Grandmed Lubuk Pakam Hospital for the period November-December 2021. The method used is a descriptive assessment because it aims to provide an objective picture or description of the situation. Data collection was carried out retrospectively. Both research by reviewing historical information, as well as data collection by observing the medical records of urinary tract infection patients at Grandmed Lubuk Pakam Hospital in 2021
ANTIDIABETIC ACTIVITY TEST OF ETHANOL EXTRACT BROCOLI (BRASSICA OLERACEA VAR. ITALICA) IN WHITE MALE RATS Novandi Purba; Diah Tri Handayani; Kristian Cahayani Zebua
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1587

Abstract

Diabetes is a chronic disease characterized by excessive blood glucose levels caused by absolute and relative insulin deficiency. The stages in this study were sampling, identification of samples/plants, simplification, simplification screening, and preparation of extracts by maceration. The method used in the diabetes activity test uses a glucometer to induce alloxan in rats at a dose of 150 mg/kg body weight. The test animals were 25 rats which were divided into 5 treatment groups namely CMC Na 0.5% (negative control), glibenclamide (positive control) 0.45 mg/kg body weight and EEB dose 200 mg/kg body weight, 400 mg/kg body weight and 600. mg/kg body weight. kg B.W. kg body weight as a test material given orally. Measurement of blood glucose values ??according to Allox and on days 3, 5, and 7 after administration of the test substance, namely EEB. The test results data were analyzed statistically using one-way ANOVA at a 95% confidence level followed by Tukey's post hoc test. The results of the phytochemical screening showed that EEB contains alkaloids, flavonoids, tannins, saponins, and glycosides. The results of the diabetes efficacy test showed that EEB doses of 200, 400, and 600 mg/kg BW had an anti-diabetic effect on male white rats. The EEB dose of 600 mg/kg is the most effective. Post hoc Tukey test results showed that EEB doses of 200 mg/kg, 400 mg/kg, and 600 mg/kg were not significantly different from the positive control glibenclamide 0.45 mg/kg (p>0.05) and 200,400 ug. and 600 mg/kg BW were significantly different from the negative control CMC Na 0.5% (p<0.05).
Co-Authors Dayana Lestari Diah Tri Handayani Dina Wahyuni Nasution Fitri Siska Imelda Oktaviani Br Sihombing Novandi Purba Romaulianna Theresia Marbun Yanna Rotua Sihombing