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All Journal Journal of Health Sciences and Medical Development
Andi Ulfiana Utari
Universitas Megarezky
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Neuroscience Veterinary

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Development and Physical Stability Test of Salak Fruit Peel Extract Mouthwash as a Plaque Preventative Nasrawati Basir; Nurfiddin Farid; Sriyanty Sadsyam; Andi Ulfiana Utari; Andi Bibit Utari Rahayu
Journal of Health Sciences and Medical Development Vol. 2 No. 02 (2023): Journal of Health Sciences and Medical Development
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/hesmed.v2i02.262

Abstract

The study aims to investigate the formulation and physical stability of salak peel extract mouthwash as a plaque preventer. Salak is a plant from Indonesia with medicinal properties, and its peel is a waste product that contains nutritional values such as protein, carbohydrates, water and low fat. The method used in this study is an experimental laboratory method. The salak peel was extracted through maceration of 96% ethanol and formulated into mouthwash with different concentrations of 5%, 10%, and 15%. The stability of the formulation was tested through organoleptic, pH, specific density, viscosity and clarity tests. The results showed no difference before and after the cycling test in organoleptic, pH, specific density, viscosity, and clarity tests, indicating the physical stability of the formulation.
Antioxidant Evaluation of Facial Toner Formulations Containing Ethyl Acetate Fraction from Garcinia Mangostana L. Fruit using ABTS 2,2'-Azinobis 3-ethyl benzothiazoline 6-sulphonic Acid Method Sriyanty Sadsyam; Nielma Auliah; Wa Ode Wisna Anto Uko; Nasrawati Basir; Andi Ulfiana Utari
Journal of Health Sciences and Medical Development Vol. 2 No. 02 (2023): Journal of Health Sciences and Medical Development
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/hesmed.v2i02.266

Abstract

The mangosteen fruit is rich in polyphenols, particularly xanthones, which have potent antioxidant effects. Given the various effects of facial toners and the growing demand for natural skincare products, mangosteen rind may serve as an alternative ingredient in facial toner formulations. This laboratory experimental study aimed to assess the antioxidant activity of facial toner preparations containing the ethyl acetate fraction of mangosteen rind (Garcinia mangostana L.) using the ABTS method at different concentrations (0.2%, 0.4%, and 0.6%). Four facial toner formulas were formulated, with Formula 1 being the control formula without any active substance and Formulas 2-4 containing the ethyl acetate fraction of mangosteen rind at different concentrations. The prepared formulas underwent physical and chemical stability tests, including organoleptic, homogeneity, pH, viscosity, and humidity tests, before and after six cycles of cycling. The antioxidant activity of the formulas was also evaluated using the ABTS method. The results showed no significant difference (p>0.05) in the organoleptic, viscosity, pH, and humidity tests before and after cycling. Formula 3 showed significant (p<0.05) antioxidant activity compared to the other formulas. Therefore, it can be concluded that the ethyl acetate fraction of mangosteen rind (Garcinia mangostana L.) can be formulated into a facial toner with potent antioxidant activity.
Co-Authors Andi Bibit Utari Rahayu Farid, Nurfiddin Nasrawati Basir Nielma Auliah Sriyanty Sadsyam Wa Ode Wisna Anto Uko