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All Journal Proceedings of the International Conference on Nursing and Health Sciences Prosiding Seminar Informasi Kesehatan Nasional Usada Nusantara: Jurnal Kesehatan Tradisional
Kharisma Jayak Pratama
Universitas Duta Bangsa Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Veterinary

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Characteristic and Antibacterial Activity Test of Red Betel Leaf Essential Oil Against Propionibacterium Acne Bacteria Bangkit Riska Permata; Kharisma Jayak Pratama; Mei Ika Nurul Khotimah; Sabrina Karim
Proceedings of the International Conference on Nursing and Health Sciences Vol 4 No 1 (2023): January-June 2023
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v4i1.1688

Abstract

Many Indonesian plants have the potential to have anti-acne activity, one of which is the red betel plant. Red betel leaf (Piper crocatum) contains flavonoids, alkaloids, tannins, and essential oils which are thought to be used as antimicrobials. The purpose of this study was to test the quality characteristics and test the antibacterial activity of red betel leaf essential oil against Propionibacterium acne bacteria. This research was an experimental study by identifying the physical quality and testing the antibacterial activity of the essential oil. human senses with the results of the smell or aroma obtained, namely the strong or stinging characteristic odor of red betel. The color of the essential oil obtained was yellow with a little brownish, bitter taste, the pH obtained from the essential oil was 4.65, the specific gravity of red betel leaf essential oil was 0.739, the ethanol soluble test obtained from the essential oil completely dissolved and white clear in a quantity of alcoholic solution. Antibacterial activity test results with red betel leaf essential oil concentrations of 5%, 10%, and 20%, could inhibit antibacterial of 7.16 mm, 10.3 mm, and 11.6 mm.
PENETAPAN KADAR FENOLIK SERTA UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI BATANG BAJAKAH KALALAWIT (Uncaria gambir Roxb) DENGAN METODE FRAP Siti Nur Indriyah; Desy Ayu Irma Permatasari; Kharisma Jayak Pratama
Usada Nusantara: Jurnal Kesehatan Tradisional Vol. 1 No. 2 (2023): Juli : USADA NUSANTARA
Publisher : Sekolah Tinggi Agama Buddha Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v1i2.347

Abstract

Antioxidants are compounds prevent oxidative damage by stabilizing free radicals by donating electrons. Phenolics are compounds that can be used as antioxidants because they can counteract free radicals. This study aims to determine the total phenolic content and antioxidant activity of the extract and fraction of the kalalawit (Uncaria gambir Roxb) stem. Extract preparation by maceration using 96% ethanol solvent. Testing for phenolic content with the Folin Ciocalteu method using UV-Vis spectrophotometry on extracts. Antioxidant activity test using the FRAP method on extracts with concentrations of 80, 90, 100, 110, and 120 ppm. The test results showed that the extract of the bajakah kalalawit stem (Uncaria gambir Roxb) had a phenolic content of 31.734 mg GAE/gr sample, there was antioxidant activity in the extract and fraction of the stem of the kalalawit (Uncaria gambir Roxb) indicated by the formation of a purplish blue color when reacted with FRAP solution , and the IC50 value of the ethanol extract was 29.842 ppm which was in the very strong category, water fraction was 39.865 ppm which was in the very strong category, n-hexane fraction was 75.319 ppm which was in the strong category and ethyl fraction was 12.572 ppm which was very strong.      
EVALUASI RASIONALITAS ANTIDIABETIK PASIEN RAWAT JALAN DIABETES MELITUS TIPE 2 DI RSAU DR. SISWANTO TAHUN 2022 Amanda Anisawati; Kharisma Jayak Pratama; Kusumaningtyas Siwi Artini
Prosiding Seminar Informasi Kesehatan Nasional 2023 : SIKesNas 2023
Publisher : Fakultas Ilmu Kesehatan Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/sikenas.vi.2835

Abstract

Diabetes melitus tipe 2 merupakan penyakit kronis akibat keabnormalan pada proses sekresi insulin, resistensi insulin ataupun akibat faktor pola hidup yang kurang sehat, sehingga perlu adanya terapi untuk menunjang kualitas hidup penderita. Terapi rasional antidiabetik menjadi salah satu parameter keberhasilan terapi optimal bagi pasien diabetes. Ketepatan terapi dapat dilihat berdasarkan kondisi pasien dan hasil tes gula darah HbA1c ≥6,5%. Penelitian ini dilaksanakan di RSAU dr. Siswanto terhadap pasien diabetes melitus tipe 2 di tahun 2022. Adapun tujuan penelitian ini untuk mengevaluasi profil pengobatan diabetik dan kerasionalitasan terapi antidiabetik yang meliputi 3 indikator ketepatan yaitu tepat indikasi, tepat obat, dan tepat dosis. Penelitian ini termasuk non eksperimental dengan pendekatan deskriptif menggunakan resep dan data rekam medis. Hasil penelitian menunjukkan bahwa dari 114 sampel yang terdiri dari 73 perempuan dan 41 laki-laki dimana seluruhnya memenuhi kriteria inklusi dan eksklusi, dan menunjukkan pravalensi umur yang mendominasi adalah sekitar 56-65 tahun (39,3%), tercatat memiliki ketepatan indikasi sebesar 81,74%, tepat obat 81,74%, dan tepat dosis 100% yang masing-masing diolah menggunakan Microsoft Excel.
Co-Authors Amanda Anisawati Bangkit Riska Permata Desy Ayu Irma Permatasari Kusumaningtyas Siwi Artini Mei Ika Nurul Khotimah Sabrina Karim Siti Nur Indriyah