Article Per Year (5 Year)
p-Index From 2019 - 2024
0.882
P-Index
This Author published in this journals
All Journal Pharmascience Window of Health : Jurnal Kesehatan Abdimas Galuh : Jurnal Pengabdian Kepada Masyarakat Hydrogen: Jurnal Kependidikan Kimia Journal Microbiology Science
Selpida Handayani, Selpida
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
Uji Aktivitas Antioksidan Ekstrak Etanol Sabut Buah Pinang (Areca catechu L.) Pratiwi, Indah; Hasnaeni, Hasnaeni; Handayani, Selpida
Jurnal Pharmascience Vol 11, No 1 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.16811

Abstract

Penelitian ekstrak etanol buah pinang (Areca catechu L.) telah dilakukan. Penelitian ini untuk mengetahui nilai IC50 antioksidan optimal buah pinang (A. catechu L.) menggunakan metode DPPH. Sampel buah pinang (A. catechu L.) diekstraksi dengan etanol 96% menggunakan metode ekstraksi maserasi. Ekstrak diuapkan untuk mendapatkan ekstrak etanol kental menggunakan rotary evaporator. Skrining fitokimia dilakukan untuk mengetahui kandungan metabolit sekunder. Hasil skrining menunjukkan adanya senyawa flavonoid dan alkaloid dalam ekstrak etanol buah pinang. Pengujian aktivitas antioksidan dilakukan dengan menggunakan DPPH dan menggunakan quercetin sebagai senyawa standar. Nilai IC50 ekstrak etanol diketahui sebesar 69,979 µg/mL. Hasil penelitian menunjukkan adanya potensi ekstrak etanol buah pinang sebagai antioksidan kuat. Kata Kunci: 2,2-Diphenyl-1-Picrylhydrazyl (DPPH), Flavanoid, Nilai IC50, Maserasi, Kuersetin The purpose of this study was to determine the optimal antioxidant IC50 value of Areca catechu L. using the DPPH method. Areca fruit extract (Areca catechu L.) with 96% ethanol using maceration procedure. The extract was evaporated using a rotary evaporator to obtain concentrated ethanol extract, after which a phytochemical screening was carried out to determine the content of secondary metabolites. Screening results showed that flavonoids and alkaloids were found in the ethanol extract of areca nut coconut shells. In addition, antioxidant activity was also tested with DPPH and uses quercetin as a standard. The IC50 of 96% ethanol extract is 69,979 µg/mL. In this review, IC50 results were obtained which showed the potential of A.catechu  ethanol extract as a strong antioxidant
Antibacterial Activity of Ethanol Extract of Purple Kencana Leaves (Ruellia tuberosa L.) Using TLC-Bioautography and Agar Diffusion Methods Sari, Felisa Ananda; Herwin, Herwin; Handayani, Selpida
Journal Microbiology Science Vol 3, No 2 (2023)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v3i2.982

Abstract

Kencana Ungu Leaf (Ruellia tuberosa L.) is a traditional plant that has antibacterial activity. The purpose of this study was to determine the antibacterial activity of the ethanol extract of Kencana Ungu leaves (Ruellia tuberosa L.) using TLC-Bioautography and Agar Diffusion methods. Simplisia from Kencana Ungu leaves (Ruellia tuberosa L.) was extracted by maceration method and then evaporated to obtain a thick extract. Preliminary testing, namely the antibacterial screening test, active extract at a concentration of 0.5% against Escherichia coli, Shigella dysenteriae, and Salmonella thypi. The results of the antibacterial activity test using the TLC-Bioautography method using chloroform: methanol (7:1) as an eluent showed results with an Rf value of 0.89 which inhibited the growth of Escherichia coli, Shigella dysenteriae, and Salmonella thypi bacteria. While the results of testing the antibacterial activity using the Agar Diffusion method obtained the largest diameter of the inhibition zone at a concentration of 20% for Escherichia coli bacteria with an inhibition zone diameter of 12.15 mm, Shigella dysenteriae with an inhibition zone diameter of 11.72 mm, and Salmonella thypi with an inhibition zone diameter of 12.67 mm
Pemberdayaan Kader Putri Karangtaruna Desa Pucak, Maros Melalui Pelatihan Pengolahan Singkong Menjadi Produk Pangan Sehat Effendi, Nurmaya; Nurlina, Nurlina; Handayani, Selpida; Amran, Farizah Dhaifina
Abdimas Galuh Vol 6, No 2 (2024): September 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i2.14318

Abstract

Modified-cassava flour (mocaf) merupakan produk tepung dari singkong termodifikasi melalui proses fermentasi yang melibatkan bakteri asam laktat. Mocaf merupakan produk olahan singkong yang bebas protein gluten sehingga aman dikonsumsi oleh kalangan masyarakat yang intoleran dengan jenis protein ini. Hasil panen singkong yang sangat melimpah di Desa Pucak setiap tahunnya yang mencapai 68 ton per tahun tentunya dapat menjadi salah satu peluang bisnis yang tentunya bisa menaikkan nilai ekonomi komoditi unggul tersebut melalui produksi mocaf dan pengolahannya menjadi produk bernilai ekonomi lain seperti kue kering dan brownies. Kegiatan pengabdian kami ini bertujuan untuk meningkatkan pengetahuan, sikap, dan keterampilan kader putri karang taruna Bukit Kemuning, Desa Pucak, Maros dalam membuat produk pangan sehat, dalam hal ini kue kering dan brownies berbahan mocaf. Dalam mencapai tujuan ini, digunakan metode penyuluhan, diskusi interaktif, serta pelatihan untuk meningkatkan pengetahuan kelompok mitra dalam membuat cookies dan brownies berbahan dasar mocaf. Untuk mengamati dan mengevaluasi perubahan pengetahuan, sikap, dan keterampilan kader putri karang taruna sebagai mitra, kami menggunakan kuesioner pre-post tes baik sebelum dan sesudah kegiatan. Hasil kegiatan menunjukkan bahwa telah terjadi peningkatan pengetahuan, sikap, dan keterampilan mitra dalam membuat cookies dan brownies berbahan dasar mocaf. Selanjutnya, kami berharap kader putri karang taruna Bukit Kemuning, Desa Pucak, Maros dapat menerapkan dan menyebarluaskan pengetahuan dan keterampilan mereka dalam membuat cookies dan brownies berbahan dasar mocaf sehingga dapat membantu meningkatkan diversifikasi produk olahan singkong desa mereka dan menjadikannya peluang usaha yang dapat meningkatkan taraf ekonomi mereka.
Toxicity of Standardized Ethanolic Extracts from Duchesnea indica (Jacks.) Focke Plants Using the BSLT Method Waris, Risda; Handayani, Selpida; Wisdawati; Hossani, Rahni
Window of Health : Jurnal Kesehatan Vol 7 No 3 (July 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.v7i2.1328

Abstract

Duchesnea indica (jacks. ) focke., known as a medical plant that is used as raw ingredients for traditional medicines and herbs to increase the immune system because plants have the properties to cure and prevent various diseases. The objective of this study is to examine the quality of the duchesnea indica leaves extract by standardization method of specific and non specific parameters as well as the toxicity assay using using the Brine Shrimp Letality Test (BSLT). The results of specific parameter research include the identity of extracting duchesnea indica, Organoptic tests form extract samples that are used to extract thick, It's brown, Typical smell, astringent taste. The content of water soluble compounds is 18.67%, the content of ethanol soluble compounds is 0.03%, based in phytochemical screening test, the duchesnea indica leaves extract contain phenolic, flavonoid, tannin, Saponin and terpenoid. Non-specific parameters carried out include loss on drying of grounded Duchesne indica leaves at 0.029%, loss on drying of DuchesneA indica leaves extract at 0.026%, specific gravity determination at 0.83%, extract water content determination of 2.15%, total ash content is 3.70%, non-soluble acid of ash content is 1.32%. Thus, from these results, we can conclude that Duchesne indica leaf extract meets quality standards for extracting raw materials that can be used for traditional medicine. Research results: The standardized ethanol extract of duchesnea indica leaves is toxic to Artemia salina leach larvae.
Identification of Medicinal Chemicals (BKO) Piroxicam in Jamu Pegal Linu Preparations in Makassar City Hasnaeni, Hasnaeni; Handayani, Selpida; Andina, Velda
Hydrogen: Jurnal Kependidikan Kimia Vol 12, No 1 (2024): February 2024
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v12i1.10576

Abstract

The aim of the research was to identify Piroxicam in herbal medicine for rheumatic pain circulating in Makassar. There are several traditional medicines that contain medicinal chemicals. Research has been conducted on the identification of medicinal chemicals (BKO) on several rheumatic herbs preparations in herbs shops in Makassar. The BKO which is often included in rheumatic herbs is the NSAID group, one of which is piroxicam. This inspection was conducted to know the presence of the chemical drug piroxicam contained within rheumatic herbs preparations and the samples used were 5 samples. The method used was a qualitative test using thin layer chromatography (TLC) consisting of a mobile phase mixed with n-hexane and acetone (7:3) and a stationary phase using Silica Gel GF254. The results of the TLC examination from 5 samples of herbal medicine added BKO piroxicam contained 3 samples including herbs A, B, and C because they had the same stain color at the same Rf value as the piroxicam. Some of the rheumatic herbs circulating in Makassar contain medicinal chemicals in the form of piroxicam.
Co-Authors Amran, Farizah Dhaifina Andina, Velda Hasnaeni hasnaeni, Hasnaeni Herwin Herwin, Herwin Hossani, Rahni Indah Pratiwi Nurlina Nurlina Risda Waris, Risda Sari, Felisa Ananda Wisdawati