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All Journal Journal Of Sustainable Research In Management Of Agroindustry (SURIMI) International Journal of Multidisciplinary Approach Research and Science
Abdulhalim Musa Abubakar
Modibbo Adama University
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Engineering Immunology & microbiology Social Sciences

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Production and Utilization of Insulin from Stevia Leave (Rebaudiana Bertoni) for the Treatment of Diabetes Mellitus Muhammad Abbagoni Abubakar; Babagana Gutti; Abdulhalim Musa Abubakar; Amina Mohamed Ali; Muhammad Jamil Umar Sabo
International Journal of Multidisciplinary Approach Research and Science Том 1 № 02 (2023): International Journal of Multidisciplinary Approach Research and Science
Publisher : Pt. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/ijmars.v1i02.63

Abstract

Stevia (Rebaudiana bertoni) leave, is an ancient perennial shrub mostly found in South America in countries like Paraguay and Brazil. It contains a low-calorie sweetener, which is about 300 times sweeter than sucrose. Diabetes mellitus is among the common metabolic disorders affecting about 2.8% of the world’s population and is reported to reach 5.4% by the year 2025. In this work, insulin was successfully extracted from Rebaudiana bertoni to serve as an alternative to bovine insulin extracted from animals which is devoid of the risk of transferring infectious diseases from the animals to the diabetic patient as is the case with convectional animal-based insulin. Gas Chromatography-Mass Spectroscopy (GC-MS) and Fourier Transform InfraRed (FTIR) analysis were used to analyze and determine the functional groups available in the isolated compound and the results shows that it has retention time of 14.11 min; abundance/peak area (% PA) of 86.613 %; mass number (m/z) of 413 g/mol; molecular peak ion of 149; fragmentation patterns of 7; and C20H29BrO4 as molecular formula and phthalic acid, 8-bromoctyl butyl ester as IUPAC name. The insulin was tested on three groups of rats (Rattus norvegicus) whereby the glucose level was monitored, and the result shows that the extracted insulin was found to be effective in addition to having antidiabetic effect.
Optimization of Insulin Yield from Extract of Stevia Leave (Rebaudiana Bertoni) Muhammad Abbagoni Abubakar; Abdulhalim Musa Abubakar; Musa Askira Abubakar; Dahiru Muhammad Dahiru
International Journal of Multidisciplinary Approach Research and Science Том 1 № 03 (2023): International Journal of Multidisciplinary Approach Research and Science
Publisher : Pt. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/ijmars.v1i03.86

Abstract

Stevia (Rebaudiana bertoni) leave, is an ancient perennial shrub mostly found in South America such as Paraguay and Brazil, it contains a low-calorie sweetener, which is about 300 times sweeter than sucrose. Insulin is a polypeptide hormone, which has an anabolic property, insulin has a vital role in regulation of carbohydrate metabolism, it also enhances the metabolism of fat and proteins and regulation of certain gene expression. Design expert software 10.0 was used to design the experimental data for the optimization of insulin yield in stevia (Rebaudiana bertoni) leave. Custom design with 3 factor and one response was applied, the independent variables were amount of stevia powder (g), volume of n-hexane (ml) and volume of ethyl acetate (ml) and the response is percentage of insulin yield (%). In this research work, insulin was successfully extracted from stevia (Rebaudiana bertoni) leave and the optimum yield was determined. The optimum extraction conditions for optimum yield of insulin were found to be: 5.668 g of stevia powder, 49.107 ml of n-hexane and 32.386 ml of ethyl acetate.
Traversing the Waste Spectrum: Unveiling Pakistan's MSW Landscape and Solutions Muhammad Asif; Mahmood Laghari; Azhar Abass; Mohammad Siddique; Abdulghaffaar Assayyidi Yusuf; Abdulhalim Musa Abubakar; Ahmed Abdo
Journal of Sustainable Research In Management of Agroindustry (SURIMI) Vol. 3 No. 2 (2023): SURIMI : Oktober 2023
Publisher : Politeknik Negeri Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35970/surimi.v3i2.2070

Abstract

Municipal solid waste (MSW) management must be sustainable in order to meet the Sustainable Development Goals (SDGs) and address health, environmental, and disposal challenges caused by the vast amounts of trash generated. MSW management going wrong puts locals in danger. In Pakistan, the production of municipal solid trash is rising daily. Urban settlers and other organizations gather a lot of waste in various forms, usually defiling and making our surroundings uninviting. Due to the indiscriminate dumping of various wastes, the soil quality in the metropolitan area has decreased as a result of solid and liquefied waste disposal. Significant environmental concerns regarding soil and water pollution arise from transferring contaminated garbage and mixed fluid outside of waste disposal borders. The impacts of municipal garbage disposal on soil and water quality at open waste dumping sites were the main focus of this review. Using a soil and water quality index, in many regions of the world especially in regions where waste management practices are insufficient, the contamination of soil and water owing to incorrect municipal solid waste disposal is a serious environmental hazard. Open dumping, unregulated landfilling, and illegal dumping are examples of improper waste disposal practices that can result in pollution that affects the quality of the soil and water. They must also seek to identify sustainable waste management solutions. The effect of these emitted gaseous emissions has, however, been thoroughly researched. To safeguard the environment and public health, quick action must be made to control trace element pollution.
Co-Authors Abdulghaffaar Assayyidi Yusuf Ahmed Abdo Amina Mohamed Ali Asif, Muhammad Azhar Abass Babagana Gutti Dahiru Muhammad Dahiru Mahmood Laghari Mohammad Siddique Muhammad Abbagoni Abubakar Muhammad Jamil Umar Sabo Musa Askira Abubakar