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Effect of Extract Meat Dates (Phoenix Dactylifera L.) to Oxytocin Levels in Pregnant Mice (Mus Musculus L.) Agustina, Eva; Purnamasari, Risa; Lusiana, Nova
Health Notions Vol 1 No 2 (2017): April-June 2017
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.835 KB)

Abstract

The process of spontaneous labor is sensitive to the oxytocin hormone that causes uterine smooth muscle contraction as a receptor for the start of labor. Dates contains source of carbohydrates are simple sugars, iron, potassium, selenium, calcium, and flavonoids. The purpose of this study was to determine the effect of date’s extracts (Phoenix dactilifera L) to the oxytocin hormone day 19 of gestation age of mice (Mus musculus L). This experiment devide dose of date extract into four groups, group I : control (no treatment), group II: 3 dates (3.12 mg/kg), group III 5 dates (5.2 mg/kg), and group IV 7 dates (7.28 mg/kg) to the oxytocin hormone. The research method is done by extracting palm ajwa with methanol. Treat made orally at the age of 14-19 days gestation. Measurement of oxytocin levels using ELISA at the age of pregnancy 19 days, showed the average number of levels of the oxytocin hormone in group I in the amount of 126.494 ng / L, the second group is equal to 124.169 ng / L, group III amounting to 129.041 ng / L, and group IV is equal to 132.252 ng / L. Overall extract dates with various doses of the treatment led to increased levels of the oxytocin hormone in mice. However, these increases did not show a significant effect, although the hormones oxytocin on uterine tissue of mice kept rising.
Antioxidant And Antibacterial Activities Of Methanol Extract Of Fig Fruit And Leaves (Ficus Carica L.) Agustina, Eva; Lusiana, Nova; Purnamasari, Risa; Faidah, Nurul Ilmi; Agustin, Azlinda Mitha
Journal of Islamic Medicine Vol 5, No 1 (2021): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2021
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v5i1.11376

Abstract

Background: Fig plants (Ficus carica L.) have phytochemical contents such as polyphenols, flavonoids, and anthocyanins which are relatively high. The content of this active compound can be used as an antioxidant and antibacterial. Objectif: The study aims to determine the antioxidant and antibacterial activity of methanol extracts fruit and leaves of fig (Ficus carica L.). Methods : DPPH method was carried out to determine the antioxidant fruit and leaves of fig (Ficus carica L.) by observing the change in colour of the test sample after incubation with DPPH solution using a UV-Vis spectrophotometer at a wavelength of 517 nm. The antibacterial test uses disc paper diffusion test to see the inhibition zone formed and continued with the MIC and MKC tests. Results : The antioxidant test results showed the IC50 values in methanol extracts of fig fruits were 13.402 ppm and 7.9875 ppm for fig leaves. From the IC50 value, both the fruit and fig leaves are classified into a solid antioxidant compound. The antibacterial test results showed that the highest inhibitory diameter was found at a 100% concentration of 28.5 mm. The quantitative antibacterial activity test showed that the methanol extract of fig fruit had a MIC value at a concentration of 80% and a MKC value at a concentration of 100%. The optimal strength as an antibacterial from fruit extracts and leaves is 100% concentration. Conclusion : The results showed the methanol extract of fig (Ficus carica L.) has potential as an antioxidant and antibacterial compound.Keyword : Antioxidant, Antibacterial , Fig Plants
Pengaruh Paparan Linear Alkylbenzene Sulfonates (LAS) dan Logam Berat Tembaga (Cu) terhadap Pertumbuhan Sagittaria lancifolia Nabila, Salsa; Purnamasari, Risa; Agustina, Eva; Irawanto, Rony
Jurnal Jeumpa Vol 10 No 1 (2023): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v10i1.7537

Abstract

Berbagai jenis limbah dapat menyebabkan pencemaran perairan, termasuk limbah domestik yang mengandung surfaktan LAS dan limbah industri yang mengandung logam berat seperti tembaga (Cu). Kadar pencemar yang tinggi dapat mempengaruhi metabolisme dan menyebabkan kematian pada organisme. Salah satu solusi untuk mengatasi pencemaran ini adalah dengan fitoremediasi, di mana tanaman Sagittaria lancifolia digunakan untuk menyerap pencemar LAS dan logam Cu. Namun, respon pertumbuhan tanaman ini terhadap pencemaran LAS dan logam Cu belum diketahui dengan detail. Untuk itu, penelitian ini bertujuan mengetahui adanya paparan LAS dan logam Cu terhadap respon pertumbuhan tanaman Sagittaria lancifolia. Penelitian ini menggunakan metode Rancangan Acak Lengkap (RAL) dengan 4 perlakuan dan 3 ulangan, di mana setiap perlakuan memiliki konsentrasi pencemar yang berbeda, yaitu 0 ppm (kontrol), LAS 10 ppm + Cu 3 ppm, LAS 30 ppm + Cu 3 ppm, dan LAS 50 ppm + Cu 3 ppm. Hasil penelitian menunjukkan bahwa paparan LAS dan logam Cu pada konsentrasi yang berbeda tidak memiliki efek signifikan terhadap pertumbuhan dan morfologi tanaman Sagittaria lancifolia. Oleh karena itu, tanaman tersebut memiliki potensi sebagai opsi untuk fitoremediasi perairan yang tercemar oleh LAS dan logam Cu.