Indra Yudhawan
Universitas Jenderal Soedirman

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BEETROOT (Beta vulgaris L.) AND ITS POTENTIAL AS AN ANEMIA TREATMENT IN PREGNANCY Synta Haqqul Fadlilah; Dalri Muhammad Suhartomo; Rizak Tiara Yusan; Indra Yudhawan
Medical and Health Journal Vol 3 No 1 (2023): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2023.3.1.9070

Abstract

Anemia is one of the most common nutritional problems in pregnant women. It is defined as a condition in which the hemoglobin (Hb) level is lower than normal. The main cause of anemia in obstetrics is iron deficiency. To prevent this condition, the Government of Indonesia through the Ministry of Health made a rule by giving iron tablets to pregnant women at least 90 tablets during pregnancy (Kemenkes RI, 2022). However, some people are often bored with this pharmacological therapy due to the nausea and vomiting effect of the iron smell. Therefore, the development of alternative anemia therapy has been done to minimize those problems. One of the herbal ingredients that are being studied for its potential as anti-anemia in pregnancy is beetroot (Beta vulgaris L.). This research is included in the type of literature review. The selected literature is research articles published in the last 10 years (2013 to 2023). There are 10 articles that match the topic of study. A total of 7 publications demonstrated the effect of beetroot on anemia in pregnant women during the pregnancy period, and 2 articles in the post-partum period. A study performed in vivo experiments on pregnant female rats. Almost all of the studies did intervention by giving subjects beetroot juice. Only one study used beets as an intervention as ice cream. The results show that beetroot has the potential to prevent and treat anemia in pregnancy by increasing hemoglobin levels and the amounts of hematocrit. It contains a high level of folic acid which is important for normal cell and tissue growth. The iron content of beetroot also plays an essential role in the human body transporting oxygen to red blood cells, so it helps to cure anemia.
Identifikasi Bahan Kimia Obat (BKO) dalam Sediaan Jamu Pegal Linu dari Kota Wonosobo Alvisnayna Aida Maharani; Perdana Priya Haresmita; Arief Kusuma Wardani; Khusnul Fadhilah; Indra Yudhawan
Jurnal Pharmascience Vol 10, No 2 (2023): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i2.15783

Abstract

Obat tradisional adalah ramuan atau bahan berupa tumbuhan, hewan, mineral, sediaan sarian (galenik), atau campuran dari bahan tersebut yang secara turun-temurun telah digunakan untuk pengobatan. Obat tradisional yang banyak diminati masyarakat salah satunya adalah jamu pegal linu. Meningkatnya permintaan pasar akan jamu membuat adanya produsen yang secara langsung menambahkan Bahan Kimia Obat (BKO) pada produknya. Tujuan penelitian ini untuk mengidentifikasi apakah terdapat kandungan BKO pada produk jamu pegal linu yang beredar di Kota Wonosobo. Metode yang digunakan adalah Kromatografi Lapis Tipis (KLT) dengan fase diam silika gel 60 F254, fase gerak etil asetat:kloroform (4:1), etil asetat:kloroform (1:1) dan etil asetat:n- heksan (3:2) dengan deteksi sinar UV254 nm. Pada penelitian ini digunakan 6 sampel jamu dengan baku pembanding parasetamol, asam mefenamat, prednison dan natrium diklofenak. Berdasarkan hasil penelitian ini, sampel yang positif mengandung BKO adalah sampel A dan E, yaitu positif mengandung prednison dengan nilai Rf 0,275. Kata Kunci: Obat Tradisional, Parasetamol, Asam Mefenamat, Prednison, Natrium Diklofenak Traditional medicines are mixtures or concoctions made from substances such as plants, animals, minerals, herbal preparations, or combinations of these substances that have been utilized for therapeutic purposes for many years. Herbal remedies for stiff and aching muscles are one of the ancient treatments that are in high demand by the general public. Producers have been forced to directly add Medicinal Chemicals to their products as a result of the rising market demand for herbal medicine. The goal of this study was to determine whether herbal products used to treat rheumatic pain in Wonosobo City included any medicinal chemicals. Thin Layer Chromatography (TLC) was the technique employed, with silica gel 60 F254 serving as the stationary phase and the mobile phases being ethylacetate:chloroform (4:1), ethyl acetate:chloroform (1:1), and ethyl acetate:n-hexane (3:2). using UV254 nm light detection. Six herbal medicine samples were employed in this trial, along with industry-standard doses of paracetamol, mefenamic acid, prednisone, and diclofenac sodium. According to the study's findings, samples A and E tested positive for the presence of pharmaceutical compounds because they contained prednisone, which had an Rf value of 0.275.