Nurdiana Nurdiana
Department Of Pharmacology, Faculty Of Medicine, Universitas Brawijaya, Malang, East Java, Indonesia

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REDUCING LUPUS PATIENTS' HOPELESSNESS THROUGH BEAUTY CLASS IN MALANG CITY IN HONOR OF WORLD LUPUS DAY Cesarius Singgih Wahono; Elvira Sari Dewi; Tri Wahyudi Iman Dantara; Perdana Aditya Rahman; Kusworini Handono; Nurdiana Nurdiana; Hani Susianti; Dian Hasanah; Choirinnisa Meilia Ayu Putri; Nora Ariyanti; Handono Kalim
Caring : Jurnal Pengabdian Masyarakat Vol 2, No 3 (2022): CARING Jurnal Pengabdian Masyarakat (Desember 2022)
Publisher : Caring : Jurnal Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.caringjpm.2022.002.03.4

Abstract

Lupus is a systemic autoimmune rheumatic disease with mild to severe clinical features and can lead to hopelessness if not treated properly. The purpose of this activity is to give a beauty class and see how it affects the hopelessness of lupus patients in honor of World Lupus Day. Methods: Organizing World Lupus Day activities such as experts seminars on lupus at a glance, being friendly with lupus, and staying beautiful with lupus; a musical drama and dance performance by a lupus support group with the theme “You Are Beautiful”; and a lupus beauty class. The activity was completed in one day in May 2018 by collecting pre-test and post-test data on the incidence of hopelessness in lupus patients using the Beck Hopelessness Scale (BHS). A total of 100 lupus patients participated in the activity, and all of them underwent pre- and post-testing. The Wilcoxon Signed Rank Test with α=0.05 was used to analyze the collected data. Results: All participants expressed delight and satisfaction with their participation in this activity. The mean BHS scores before and after the beauty class were 8.62+2.68 and 6.36+1.59, respectively, with a significant difference (p=0.000). Conclusion: Beauty class is a fun way for lupus patients to feel less hopeless about their illness. Every year, an activity to commemorate World Lupus Day is required, which is beneficial for lupus patients.
Lime (Citrus aurantifolia (Christm.) Swingle) Juice Potential on Preventing Lipid Profile Aberrations as Alternative to Lemon (Citrus limon (L.) Burm.f.) Juice Olivia Anggraeny; Keshya Venesa; Nadia Magdalena; Stefany Dame; Sylvia Winnie; Stephani .Nesya; Nurdiana .
Indonesian Journal of Human Nutrition Vol. 7 No. 2 (2020)
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijhn.2020.007.02.7

Abstract

ABSTRAKHiperlipidemia merupakan penyebab dari berbagai penyakit degeneratif. Mengonsumsi air perasan lemon menjadi tren di Indonesia beberapa tahun ini. Pada penelitian ini, dilakukan perbandingan efektivitas air perasan lemon dan jeruk nipis. Tujuan dari penelitian ini adalah untuk menganalisis perbedaan profil lemak darah: kolesterol total, low density lipid (LDL), very low density lipoprotein (VLDL), dan trigliserida (TG) pada tikus yang diberi diet tinggi lemak, air perasan lemon, dan jeruk nipis. Penelitian ini menggunakan 32 tikus jantan galur Wistar yang dibagi menjadi 8 kelompok dosis perlakuan air perasan lemon dan jeruk nipis. Didapatkan hasil bahwa tidak ada perbedaan kadar LDL (P0.151; p<0.05), VLDL (P0.187; p<0.05), TG (P0.216; p<0.05), namun ditemukan perbedaan signifikan pada kadar kolesterol total (P0.003; p<0.05). Hewan coba yang diberi perlakuan jeruk nipis memiliki sebagian besar rerata kadar lemak yang tidak berbeda signifikan dengan kelompok perlakuan lemon. Meskipun demikian, kolesterol total pada kelompok jeruk nipis lebih rendah dibandingkan kelompok lemon. Konsumsi jeruk nipis tampaknya memiliki kemungkinan menjadi alternatif dari lemon yang lebih murah dan terjangkau untuk mencegah profil lemak yang buruk.   Kata kunci: lemon, jeruk nipis, kolesterol total, LDL, VLDL, TGABSTRACTHyperlipidemia causes various degenerative diseases. Recently, consuming lemon juice has become a trend in Indonesia to improve blood lipid profiles. This study compared the effectiveness of lemon juice and lime juice. This study aimed to determine differences in blood lipid profile that contains total cholesterol (TC), low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and triglycerides (TG) in rats given High Fat Diet (HFD), lemon juice, and lime juice. This study used 32 white male Wistar rats (Rattus norvegicus) divided into eight treatment groups of lemon and lime juice doses. The results showed no significant differences in LDL (P0.151; p<0.05), VLDL (P0.187; p<0.05), and TG (P0.216; p<0.05), but there were significant differences in total cholesterol levels (P0.003; p<0.05). The experimental animals receiving lime juice had mean scores of lipid levels that were not significantly different from those with lemon treatment. However, the total cholesterol levels among groups given lime juice showed lower levels than the control and lemon treatment groups. Lime consumption seems possible to be a cheaper and affordable alternative to lemon to prevent lipid profile aberrations.Keywords: lemon, lime, TC, LDL, VLDL, TG
Correlation between Secreted Aspartyl Protease-5 (SAP5) on Increasing Vaginal Acidity in Vulvovaginal Candidiasis Nur Sophia Matin; Regina Ayu Fristiyanti; Safrina Dewi Ratnaningrum; Nurdiana Nurdiana; Sanarto Santoso; Bambang Rahardjo
Asian Journal of Health Research Vol. 2 No. 2 (2023): Volume 2 No 2 (August) 2023
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v2i2.116

Abstract

Introduction: Vulvovaginal candidiasis (VVC) is an infection of the vaginal mucosa that extends to the vulva due to excessive growth of Candida albicans, causing a progressive decrease of Lactobacillus spp., as the main of normal flora. Decrease in the number of Lactobacillus spp. causes a reduction of lactic acid production that it was causing increasing vaginal pH. The increase in pH is due to the progressive growth of C. albicans colonies in the vaginal mucosa. In addition, the mechanism of candidiasis is also influenced by the secretion of virulence factors by C. albicans. Secreted Aspartyl Protease-5 (SAP5) is the dominant virulence factor that plays a role in changing the morphology of yeast cells into hyphae. This study aims to identify the correlation between SAP5 levels and vaginal pH. Material and Methods: This research was conducted in vivo using a sample of Rattus norvegicus with a posttest randomized experimental group design approach. This study has two groups, i.e., Negative Control (NC) and Positive Control group (PC). SAP5 and pH samples were taken from vaginal fluids and then measured using ELISA and a digital pH meter. The statistical analysis used was Pearson Correlation to analyze the correlation between SAP5 and pH levels. Results: There was a strong correlation (R=0.846) that means the increase of SAP5 is related to the increase of vaginal acidity in the PC group. Conclusion: The increase in SAP5 levels is directly followed by an increase in the pH value of vaginal fluids,
Hubungan Keterampilan dengan Kesiapsiagan Perawat dalam Menghadapai Bencana Kabut Asap Nurdin; Nurdiana; Yati sri hayati
Jurnal Ilmiah Kesehatan Mandala Waluya Vol. 1 No. 1 (2021): Jurnal Ilmiah Kesehatan Mandala Waluya
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54883/jikmw.v1i1.634

Abstract

Hampir seluruh bagian negara di dunia pernah mengalami kebakaran hutan seperti Amerika Serikat, Australia, Yunani, Swaziland, termasuk Indonesia. Salah satu efek dari kebakaran hutan dan lahan yang terjadi di Indonesia dalah bencana kabut asap. Data BNPB pada tahun 2015 terkait dampak bencana kabut asap, terdapat 503.884 penderita ISPA yang tersebar diberbagai provinsi seperti Sumatra selatan, Riau, Jambi, Kalimantan selatan, tengah dan barat, serta menimbulkan korban jiwa sebanyak 26 orang. Selain itu, dampak kabut asap menimbulkan kerugian ekonomi sangat besar mencapai 200 triliun rupiah dan 43 juta penduduk terpapar kabut asap. Tujuan penelitian ini untuk menganalisis hubungan keterampilan dengan kesiapsiagaan perawat puskesmas dalam menghadapi bencana kabut asap di Kota Pontianak. Metode yang digunakan survei analitik dengan pendekatan cross sectional study dengan jumlah responden 90 perawat puskesmas secara simple random sampling. Pengukuran kesiapsiagaan perawat menggunakan kuesioner Emergency Preraredness Information Questionnaire. Hasil uji spearman ranks menjelaskan terdapat hubungan antara keterampilan dengan kesiapsiagaan perawat puskesmas dalam menghadapi bencana kabut asap di kota Pontianaknilai (p = 0.000) dimana nilai p < α, adapun dengan nilai r = 0.412, menjelaskan hasil interpretasi korelasi arah positif dengan makna kekuatan hubungan sedang. Keterampilan adalah faktor yang merupakan salah satu faktor yang penting dalam menghadapi bencana kabut asap di Kota Pontianak.