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All Journal International Journal of Public Health Science (IJPHS) Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Oceana Biomedicina Journal Indonesian Journal of Global Health research Jurnal Impresi Indonesia Oceana Biomedicina Journal Hang Tuah Medical Journal Prominentia Medical Journal Journal of Pharmaceutical and Sciences. JPMP
Ronald Pratama Adiwinoto
Hang Tuah University
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Jurnal Kedokteran Anatomica (Anatomica Medical Journal)

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The Hygiene Hypothesis And Covid-19: A Look At The Evidence And New Perspectives Peppy Nawangsasi; Ronald Pratama Adiwinoto; Verna Biutifasari; Tamam Jauhar; Wahyu Prasasti Mutiadesi
ANATOMICA MEDICAL JOURNAL | AMJ Vol 6, No 3 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/amj.v6i3.15787

Abstract

The hygiene hypothesis postulates that early-life exposure to infectious agents and microbes has a significant impact on the maturation of the immune system, providing protection against allergies and autoimmune diseases.Recent studies have challenged the hypothesis's universality, suggesting that it might only be relevant in developed countries. New perspectives on the hygiene hypothesis propose a multifaceted theory that considers not only microbial exposure but also factors such as diet, stress, and the environment. The role of specific immune cells in the development of allergies and autoimmune diseases has been emphasized, and innovative therapies based on manipulation of immune cells have been proposed. The importance of reconciling the hygiene hypothesis with recent insights into the human microbiome and the importance of maintaining a balance between hygiene and microbial exposure is also emphasized. Lastly, the article delves into the hygiene hypothesis, investigates the connection between gut microbiota dysbiosis and the development of allergies and autoimmune diseases, and examines the influence of COVID-19 on both gut microbiota and immune function.Keywords: allergies and autoimmune diseases, gut microbiome dysbiosis
Co-Authors Agung Dwi Wahyu Widodo Angelica Kresnamurti Astrid Kusuma Cahya Yudha Laksmana Putra Erina Yatmasari Ersanda Nurma Florentina Sustini Hardiono Hardiono, Hardiono Helda Dwiana Sari Hidajat, Boerhan I Made Dwi Mertha Adnyana Ida Ayu Govinda Lazenobia De Sanjaya Putri Izzah Al Nabilah Jongky Hendro Prajitno Ketut Edy Sudiarta Lavenda Diarnasa Zihara Safira Levina Larassanti Liliawanti Liliawanti M. Shadiqul Amin Made Ayu Mira Cyntia Dewi Made Maylisca Theresia Mulya Diprasta Made Peni Juliana Maliku Nurrochman Widandi Manata Wijaya Sasmita Maulana Muchammad Aunun Najib Meiriyanti Dhita Mentari Nata Kusuma Michael Bramantya Michelle Madeline Maydavania Mita Herdiyantini MOCHAMAD ALVIRIO NEDYA RIZKA Muhammad Kalaznykov MUHAMMAD RIZAL NANDA ABIGAIL Oki Nugraha Putra Oki Nugraha Putra Peppy Nawangsasi Pramudita Riwanti Retno Budiarti Riami Robert Dwitama Adiwinoto Sadya Wendra Sulistiawati Sulistiawati Sylvia Rizki Tamam Jauhar Tamam Jauhar Usman Hadi Verna Biutifasari Wahyu Prasasti Mutiadesi