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All Journal NUSANTARA: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmu Kesehatan dan Gizi Jurnal Pengabdian Masyarakat Indonesia Sejahtera The Journal General Health and Pharmaceutical Sciences Research Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran
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Journal : Jurnal Ilmu Kesehatan dan Gizi

 1 
Formulasi Gel Sabun Wajah Ekstrak Etanol Daun Putihan (Chromolaena odorata L.) Sebagai Antijerawat Monica Suryani; Manahan Situmorang; Steven Tandiono
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 1 (2023): Januari: Jurnal Ilmu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (577.42 KB) | DOI: 10.55606/jikg.v1i1.959

Abstract

Acne is a skin disease due to chronic inflammation with complex pathogenesis. The public has empirically used the white plant to treat wounds on the skin, it contains flavonoids, saponins, and tannins which can protect the skin from bacteria and can inhibit bacterial growth. This study aims to test the antibacterial activity against Propionibacterium acnes. The ethanol extract of Putihan leaves was obtained by maceration using 96% ethanol solvent, formulated and evaluated for facial soap gel preparations of ethanol extract of Putihan leaves with various extract concentrations of 0% (F0), 10% (F1), 13% (F2), and 15% (F3) which testing antibacterial activity against Propionibacterium acnes. The results showed that the antibacterial activity of the facial soap gel preparation of ethanol extract of Putihan leaves with a concentration of 10% had an inhibition of 8.4 ± 0.20 mm, 13% had an inhibition of 9.5 ± 0.23 mm and 15% had an inhibition of 10.6 ± 0.64mm. Based on this description, the resulting gel preparation has antibacterial activity against Propionibacterium acne. The three formulas are included in the medium inhibition zone category, but the one with the broadest inhibition zone is at a concentration of 15%.
Evaluasi Kombinasi Infusa Daun Sirih (Piper betle L.) dan Infusa Rimpang Jahe (Zingiber officinale-Roscoe) terhadap Tikus Jantan (Rattus norvegicus) Galur Wistar Sebagai Model Hiperglikemia Dhea Nur Fadhilah; Manahan Situmorang; Dumartina Hutahuruk; Julia Susanti
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1731

Abstract

Hyperglycemia occurs when the body's condition is too much blood glucose that exceeds normal limits in the body because the body does not produce insulin properly. Betel leaves and ginger rhizomes have long been used by the people in Indonesia as traditional medicines that are believed to reduce blood glucose levels. This study aims to determine the effectiveness of betel leaves and ginger rhizomes empirically to reduce blood glucose levels in hyperglycemia male rats. Betel leaves and rhizomes of ginger are made in the form of infusions and used on 30 heads of hyperglycemia mice divided into 6 groups. Normal group, negative group induced alloxane, positive group (glibenklamide), betel leaf infusion group, ginger rhizome infusion group, betel leaf infusion combination group and ginger rhizome infusion, testing was carried out for 30 days. Data were analyzed with IBM SPSS 20.0 ANOVA and post hoc tukey HSD assays. The results showed that betel leaf infusion at a dose of 2 ml / kg BB and ginger rhizome infusion dose of 2ml / kg BB single administration could reduce blood glucose levels while in combination administration it was seen that there was less effective in reducing blood glucose levels in male white rats.
Co-Authors Cut Masyitah Thaib Dhea Nur Fadhilah Dumartina Hutahuruk Jon Kenedy Marpaung Julia Susanti Monica Suryani Natanael Priltius Siti Nurbaya Steven Tandiono Supartiningsih - -