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All Journal Indonesian Journal of Global Health research MEDIC MEdical Dedication
Fairuz Fairuz
Universitas Jambi
Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Physics Public Health

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Journal : Indonesian Journal of Global Health research

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Incidence of Gingival Mucosa Karyolysis in the Use of Food Coloring as A Dental Plaque Detection Material (Study on Mus Musculus)” Naning Nur Handayatun; David Rudi; Karin Tika Fitria; Fairuz Fairuz
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3245

Abstract

Bacteria in dental and oral diseases can lead to systemic issues like kidney and heart disease, emphasizing the importance of maintaining oral hygiene. Disclosing solution, a plaque-revealing agent, is pivotal in assessing plaque removal efficacy. The optimal concentration of rose pink food coloring for plaque visibility is 2.5 g/20 ml water. However, the potential impact of this coloring on oral epithelium remains unstudied. Objective: This research aimed to evaluate the effect of disclosing solution food coloring on the gingival mucosal layer in mice. Pure experimental research with a control group design involved 6 mice (Mus musculus) each in treatment and control groups. Erythrocyn, derived from rose pink food coloring, was applied to mice’s gingiva for 2 minutes daily over 7 days. Labio-gingival epithelial cells were then sampled and analyzed using the modified Feulgen-Roseenbeck method. 58.33% of mice showed karyolysis in gingival epithelial cells, contrasting with no karyolysis in lip mucosa. Careful management of food coloring-containing erythrosine as a plaque detection agent is crucial to prevent contact with oral mucosa or prompt cleaning if contact occurs.
Co-Authors David Rudi Hanina, Hanina Hasna Dewi Iskandar, Mirna Marhami Karin Tika Fitria Lipinwati Lipinwati Naning Nur Handayatun