Yudied Agung Mirasa
Technical Centre for Environmental Health and Disease Control, Ministry of Health Republic Indonesia, Surabaya 60175, Indonesia

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Refill Drinking Water Depot Risk Assessment for Chemical Hazard Contaminant in 25 Cities of East Java Province, Indonesia Yudied Agung Mirasa; Siti Nurhidayati; Rania Wicaksono; Winarko Winarko; Kholifah Firsayanti Juwono; Zainul Amiruddin Zakaria; Khuliyah Candraning Diyanah; Aditya Sukma Pawitra; Moch. Sahri
JURNAL KESEHATAN LINGKUNGAN Vol. 16 No. 2 (2024): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v16i2.2024.166-172

Abstract

Introduction: Water was a part of the environment that was very susceptible to contamination by various hazardous substances, both physical, chemical, and microbiological. Serious health problems might occur when humans consume contaminated drinking water and can cause infectious and non-infectious diseases. This study aimed to analyze the risk quotient of chemical hazard exposure in drinking water by depot refilling drinking water from 25 cities and regencies in East Java Province. Methods: This study was analytically observational with a cross-sectional research design. The sampling method used was porposive sampling, which took 25 from 38 cities and regencies in East Java province. There were three steps to analyze drinking water health risks: dose-response analysis, exposure path, and risk characteristics analyzed. Results and Discussion: The highest concentrations of each parameter parameter F (1.4132 mg/L), NO_3 (56.2780 mg/L), NO_2 (22,225 mg/L), Fe (0.3845 mg/L), Mg (4.54 mg/L), and Zn (0.4272 mg/L). Analysis of risk quotient > 1 for parameters NO_3 (1.2265), NO_2 (7,748), and Mg (1.1308) Indicates that drinking water in the area is not safe for consumption by people weighing 55kg as much as 2L/day for 350 days. Conclusion: Based on the results of studies conducted on those substances (F, NO_3, NO_2, Fe, Mg, and Zn) there are three substances in the water that have RQ value > 1, NO_3 (1.2265), NO_2 (7,748), and Mg (1.1308) this means that those substances are risking human health and needed to be addressed controlled.
Phylogenetic Analysis and Mutation of Sars-Cov-2 in Bats in Karst Malang City, Indonesia Soedjajadi Keman; Moch Irfan Hadi; Dedy Suprayogi; Yudied Agung Mirasa
JURNAL KESEHATAN LINGKUNGAN Vol. 16 No. 2 (2024): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v16i2.2024.173-180

Abstract

Introduction: A group of people in China were hospitalized with an initial diagnosis of pneumonia of unknown cause. The patients were linked to a wholesale wet seafood and animal market in Wuhan, Hubei Province, China. The disease has spread to other provinces in China, Thailand, Japan, and South Korea in less than a month. SARS-CoV-2 was found to originate from bats. Therefore, this research aims to analyze SARS-CoV-2 mutation in bats in Malang Karst, Indonesia. Methods: Other bat body parts used as research samples include the brain, liver, kidneys, intestines, pancreas, fetus, blood, lungs, and ectoparasites. The samples were taken separately and placed in a container containing 10% PBF. For further analysis, we used RNA Extraction, Real-Time PCR, Sequencing, and CoV Gisaid mutation analysis software to analyze the sequencing data. Then, EMBL software will be used to analyze the phylogenetically. Results and Discussion: There was 1 sample that showed a positive result for Covid-19, namely the intestine of the Cynoptera brachyotis species. There were differences between SARS-CoV-2 in bats in Malang Karst in Indonesia compared to SARS-CoV from 2000 to 2019. The spike protein's receptor binding domain (RBD) is the most variable part of the coronavirus genome. Conclusion: From the research results, one positive sample was obtained using Real-Time PCR, and based on mutation analysis, mutations were found in SARS-CoV-2 against the SARS-CoV virus from 2000-2019. Further research is needed, especially regarding SARS-CoV-2 as a vaccine.