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All Journal MDJ (Makassar Dental Journal)
Rafikah Hasyim
Departemen Oral Biologi Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia
Dentistry

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The potential of fucoidan extract in stimulating the growth of osteoblast cells on alveolar bonepotential of fucoidan extract in stimulating the growth of osteoblast cells on alveolar bone: Potensi ekstrak fucoidan dalam merangsang pertumbuhan osteoblas pada tulang alveolar Egita Aprilia Sukarno; Abdul Gany; Rayhan Azhar Mustakim; Andi Adinda Mustafifa; Nur Istiqamah Riyadh; Nabiel Muhammad Hilmansyah; Rafikah Hasyim
Makassar Dental Journal Vol. 12 No. 3 (2023): Volume 12 Issue 3 Desember 2023
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v12i3.790

Abstract

Alveolar bone is mineralized connective tissue with cellular components consisting of three main cell types: osteoblasts, osteo-cytes, and osteoclasts. Alveolar bone conditions can undergo resorption due to certain conditions such as bacterial invasion due to periodontal disease. Fucoidan can increase alkaline phosphate levels, collagen type-1 expression, osteocalcin, and BMP-2 and assist in mineral deposition associated with bone healing through increased osteoblasts.This review is a descriptive obser-vation through systematic and structured literature searches through PubMed, Elsevier (Scopus), Science Direct, Springer, and Jurn websites. As many 1,482 articles found, they were filtered and found as many as 5 reference articles. It is concluded that fucoidan extract can stimulate the growth of osteoblast cells with the speed of growth of osteoblast cells depending on the con-centration and amount of fucoidan given
Co-Authors Abdul Gany Andi Adinda Mustafifa Egita Aprilia Sukarno Nabiel Muhammad Hilmansyah Nur Istiqamah Riyadh Rayhan Azhar Mustakim