MDJ (Makassar Dental Journal)
Vol. 12 No. 3 (2023): Volume 12 Issue 3 Desember 2023

The potential of fucoidan extract in stimulating the growth of osteoblast cells on alveolar bonepotential of fucoidan extract in stimulating the growth of osteoblast cells on alveolar bone: Potensi ekstrak fucoidan dalam merangsang pertumbuhan osteoblas pada tulang alveolar

Egita Aprilia Sukarno (Mahasiswa Klinik Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)
Abdul Gany (Mahasiswa Klinik Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)
Rayhan Azhar Mustakim (Mahasiswa Klinik Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)
Andi Adinda Mustafifa (Mahasiswa Klinik Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)
Nur Istiqamah Riyadh (Mahasiswa Klinik Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)
Nabiel Muhammad Hilmansyah (Mahasiswa Klinik Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)
Rafikah Hasyim (Departemen Oral Biologi Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, Indonesia)

Article Info

Publish Date
01 Dec 2023

Abstract

Alveolar bone is mineralized connective tissue with cellular components consisting of three main cell types: osteoblasts, osteo-cytes, and osteoclasts. Alveolar bone conditions can undergo resorption due to certain conditions such as bacterial invasion due to periodontal disease. Fucoidan can increase alkaline phosphate levels, collagen type-1 expression, osteocalcin, and BMP-2 and assist in mineral deposition associated with bone healing through increased osteoblasts.This review is a descriptive obser-vation through systematic and structured literature searches through PubMed, Elsevier (Scopus), Science Direct, Springer, and Jurn websites. As many 1,482 articles found, they were filtered and found as many as 5 reference articles. It is concluded that fucoidan extract can stimulate the growth of osteoblast cells with the speed of growth of osteoblast cells depending on the con-centration and amount of fucoidan given

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Journal Info
MDJ (Makassar Dental Journal)
Website

Abbrev

MDJ

Publisher

Persatuan Dokter Gigi Indonesia Cabang Makassar

Subject

Dentistry

Description

The journal receives a manuscript from the following area below Dentistry science and development with interdisciplinary and multidisciplinary approach: Dental Public Health and Epidemiology Oral and Maxillofacial Surgery Dental Conservation and Endodontics Preventive Dentistry Biomedical Dentistry ...