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All Journal Indonesian Journal of Urology MNJ (Malang Neurology Journal)
Negara, Edvin Prawira
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Health Professions Medicine & Pharmacology Neuroscience Public Health

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FACTORS INFLUENCING POST-CIRCUMCISION WOUND HEALING Daryanto, Besut; Satyagraha, Paksi; Kustono, Andri; Dhani, Fauzan Kurniawan; Negara, Edvin Prawira; Purnomo, Athaya Febriantyo; Sholihah, Nikmatus; Hanggara, Dian Sukma
Indonesian Journal of Urology Vol 31 No 2 (2024)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v31i2.960

Abstract

Objective: This study aims to determine the effect of the penile gland and smegma smear, the expression of collagen and fibroblasts in the preputium, on post-circumcision wound healing. Material & Methods: A cross-sectional study conducted in Malang with samples obtained by purposive sampling on September 17, 2022. Inclusive criteria were uncircumcised males who agreed to be circumcised and had no contraindications to the procedure. Furthermore, the preputium obtained from the circumcision procedure was stained with Hematoxylin-Eosin (HE) and counted under an optical microscope. Post-circumcision evaluation was carried out seven days after the procedure. The data were analyzed using the regression method; p denotes the probability value or significance level, while the b score denotes the degree of influence. Results: There were total of 31 research samples that had a significant difference in the average age between the samples with post-circumcision complaints (11.25 ± 2.75) and those without complaints (8.5 ± 2.73) (p=0.05). The regression test found that bacterial culture, fibroblasts, and collagen had significant effects of 24%, 25%, and 24%, respectively. Conclusions: Skin elasticity decreases with age, as marked by increased fibroblasts and decreased collagen density. Fibroblast factors, collagen, and bacterial culture are significant in wound healing. Keywords: Circumcision, collagen, fibroblast, wound healing.
THE EFFECT OF HIGH-INTENSITY FOCUSED ELECTRO-MAGNETIC (HIFEM) THERAPY ON URINARY INCONTINENCE Daryanto, Besut; Kustono, Andri; Negara, Edvin Prawira
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.9

Abstract

Introduction: Urinary incontinence (UI) is an involuntary leakage of urine, regardless of the amount or frequency, which alters physical, emotional, and social well-being and quality of life. The therapy currently being studied is magnetic stimulation (MS) has been used to stimulate the pelvic floor muscles. It is based on Faraday's law of magnetic induction, where a changing magnetic field over time induces electrical activity that depolarizes nerves and causes contraction of the pelvic floor muscles. However, the research on the effect of High-Intensity Focused Electromagnetic is still minimal, especially in Indonesia, so its effectiveness in overcoming UI in Indonesia is still doubtful. Method: This study used a prospective cohort design where patients were followed for one month. Patients were followed from when they were first diagnosed until the therapy was completed and evaluated. The variables in this study were as follows: pre and post International Prostate Symptom Score (IPSS), Overactive Bladder Syndrome Score (OABSS), Barhal index, and progress of patient complaints from the first therapy. Result: This research was conducted for 6 sessions, and significant results were obtained in sessions 1, 4, 5, and 6. From this data, we conclude that the HIFEM therapy had a significant effect from session 4. Furthermore, we found a significant therapeutic effect between sessions 4 and 6, but not between sessions 4 and 5. There was also a significant therapeutic effect between sessions 5 and 6. Conclusion: HIFEM can improve incontinence and OAB complaints. HIFEM works to strengthen the pelvic floor muscles.
Co-Authors Dhani, Fauzan Kurniawan Hanggara, Dian Sukma Kustono, Andri Nikmatus Sholihah Paksi Satyagraha Purnomo, Athaya Febriantyo