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All Journal Buletin Farmatera Indonesian Journal of Cardiology JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Jurnal Pandu Husada
Ahmad Handayani
Universitas Muhammadiyah Sumatera Utara
Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Shock Index as Simple Clinical Independent Predictor of In-hospital MACEs in NSTEMI Patients Presenting with Heart Failure Handayani, Ahmad; Kaban, Kartika; Nasri, Marwan; Mukhtar, Zulfikri; Siregar, Abdullah Afif
Indonesian Journal of Cardiology Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.30701/ijc.v38i2.731

Abstract

Background: Identification of Non-ST Elevation Myocardial Infarction (NSTEMI) patientsat higher risk of in-hospital complications is very important. Such identification will givecrucial information in determining treatment strategy especially for those come with heartfailure. One of the simple predictor for short term prognosis in acute coronary syndromeis shock index (SI), which is the ratio of heart rate over systolic blood pressure on admission.There had not been any study conducted to evaluate the use of SI in NSTEMI patientscome with heart failure. The aim of this study is to evaluate the SI compared with otherroutine clinical and laboratory examination as a predictor of in-hospital major adversecardiac events (MACEs) in NSTEMI patients presenting with heart failure.Methods: We performed a retrospective analysis of NSTEMI patients with heart failureadmitted to Haji Adam Malik General Hospital in Medan from January 2014 until July 2015.SI was calculated as the ratio of heart rate over systolic blood pressure on presentation.Patients presenting with cardiogenic shock were excluded.Results: There were 55 patients eligible in this study. In-hospital MACEs was found in 24patients (44%) compared with 31 patients (56%) without in-hospital MACEs. Patientswith in-hospital MACEs were older (60.6±10.8 vs. 57.2±7.9, p=0.178), had less historyof dyslipidemia [8(33%) vs. 19 (61%), p=0.032], faster heart rate (111.4±35.8 vs.96.5±24.3, p=0.032], higher GRACE score [139(98-187) vs. 120 (91-148); p=0.001],and higher SI [0.83(0.57-1.5) vs. 0.67 (0.38-1.27), p=0.013). SI >0.8 was the only independentpredictor of MACEs in NSTEMI patients presenting with heart failure (OR=4.3,CI=1.247-14.328, p=0.048).Conclusion: Beyond other routine examinations, SI is the only independent predictor ofin-hospital MACEs in NSTEMI patients presenting with heart failure.
PERBEDAAN KEPATUHAN MINUM OBAT ANTARA LAKI - LAKI DENGAN PEREMPUAN DAN HUBUNGANNYA DENGAN KEBERHASILAN TERAPI PADA PASIEN HIPERTENSI DI KLINIK PELITA BUNDA KECAMATAN LUBUK PAKAM DINDA ETIKA SURY; AHMAD HANDAYANI
JURNAL ILMIAH MAKSITEK Vol 6 No 2 (2021): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Data from World Health Organization (WHO) 2015 showed that around 1,13 billion of people in the world are affected byhypertension, more than 1 from 4 men and 1 from 5 women in the world affected by hypertension. Adherence to medicaltreatment has a very important role towards a successful therapy. Gender is a factor that affects in the utilization of healthservices and adherence to medical treatment. This research aimed to determine the difference in adherence to medicaltreatment between man and woman and the relationship with the success of the therapy in hypertensive patiens at PelitaBunda Clinic, Lubuk Pakam. This research is a cross sectional study. The total sample for this research is 50 hypertensivepatiens at Pelita Bunda Clinic, Lubuk Pakam with a purposive sampling method. Data were analyzed with Chi-Square test.The analysis using Chi Square obtained p-value=0,382 that shows no difference in adherence to medical treatment betweenman and women and the p-value <0,05 shows that there is a significant relationship between the adherence to medicaltreatment towards blood pressure. There is no difference in adherence to medical treatment between man and women.There is a significant relationship between adherence to medical treatment towards a successful therapy.
PENGARUH AKTIVITAS FISIK RUMAHAN TERHADAP TEKANAN DARAH PADA IBU RUMAH TANGGA YANG MEMILIKI RIWAYAT HIPERTENSI DI KELURAHAN TITI KUNING GARBIE SYAHLY AGUNG; AHMAD HANDAYANI
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Based on data from the World Health Organization, it is stated that 972 million or 26.4% of people worldwide havehypertension. This high blood pressure can lead to coronary heart disease, heart failure, and stroke. According to the WorldHealth Organization (WHO), hypertension is a non-communicable disease suffered by people in Indonesia with a fairly highpercentage (57.6%). Physical inactivity can increase the risk of uncontrolled hypertension by increasing stimulation of thesympathetic system and plasma levels of catecholamines which can increase blood pressure. Housewives tend to lackphysical activity or exercise and are only limited in doing physical activities at home, especially with the current pandemicconditions which require people to do activities at home. To determine the relationship of home physical activity to bloodpressure in housewives who have a history of hypertension. This study was conducted using a categorical analytic methodwith a cross-sectional study design from September 2020 to January 2021 in Titi Kuning Village, Medan Johor District,Medan. Based on the results of the analysis, it was found that the most demographic characteristics of the age group werefound at the age of 26-35 years, namely 12 people (40%), the highest blood pressure category was in the 1st-degreehypertension group, namely 15 people (50%), moderate physical activity category being the most found, namely as many as16 people (53.3%) with a value of p = 0.001. There is a significant relationship between home physical activity on bloodpressure in housewives who have a history of hypertension.
HUBUNGAN PRODUKSI URIN DENGAN SATURASI OKSIGEN TERHADAP KEMATIAN SELAMA PERAWATAN PASIEN GAGAL JANTUNG AKUT AZZUHRA PERMATA KHAIRA; AHMAD HANDAYANI
JURNAL ILMIAH KOHESI Vol 5 No 4 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Acute heart failure has manifestations with rapid onset that needs to be treated in within 24 hours. Urine output and oxygensaturation (SpO2) are used to monitor patients in the ICU to determine the severity and prognosis ot the disease. This studyaims to determine the relationship between urine output and oxygen saturation to the death of patients during treatment.This study used analytical method with cross sectional design. The number of sample is 45, and the secondary data wascollected from the hospitals’ medical records. The results showed that the relationship of urine output with patients’ outcomeshowed a p value of 0.011 (p <0.05). While the relationship of oxygen saturation with outcome and the relationship of urineoutput with oxygen saturation both showed p values of 0.123 and 0.368 (p>0.05). There is a significant relationship betweenurine output and the acute heart failure patients’ outcome.
Shock Index as Simple Clinical Independent Predictor of In-hospital MACEs in NSTEMI Patients Presenting with Heart Failure Ahmad Handayani; Kartika Kaban; Marwan Nasri; Zulfikri Mukhtar; Abdullah Afif Siregar
Jurnal Kardiologi Indonesia Vol. 38, No. 2 April-June 2017
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v38i2.731

Abstract

Background: Identification of Non-ST Elevation Myocardial Infarction (NSTEMI) patientsat higher risk of in-hospital complications is very important. Such identification will givecrucial information in determining treatment strategy especially for those come with heartfailure. One of the simple predictor for short term prognosis in acute coronary syndromeis shock index (SI), which is the ratio of heart rate over systolic blood pressure on admission.There had not been any study conducted to evaluate the use of SI in NSTEMI patientscome with heart failure. The aim of this study is to evaluate the SI compared with otherroutine clinical and laboratory examination as a predictor of in-hospital major adversecardiac events (MACEs) in NSTEMI patients presenting with heart failure.Methods: We performed a retrospective analysis of NSTEMI patients with heart failureadmitted to Haji Adam Malik General Hospital in Medan from January 2014 until July 2015.SI was calculated as the ratio of heart rate over systolic blood pressure on presentation.Patients presenting with cardiogenic shock were excluded.Results: There were 55 patients eligible in this study. In-hospital MACEs was found in 24patients (44%) compared with 31 patients (56%) without in-hospital MACEs. Patientswith in-hospital MACEs were older (60.6±10.8 vs. 57.2±7.9, p=0.178), had less historyof dyslipidemia [8(33%) vs. 19 (61%), p=0.032], faster heart rate (111.4±35.8 vs.96.5±24.3, p=0.032], higher GRACE score [139(98-187) vs. 120 (91-148); p=0.001],and higher SI [0.83(0.57-1.5) vs. 0.67 (0.38-1.27), p=0.013). SI >0.8 was the only independentpredictor of MACEs in NSTEMI patients presenting with heart failure (OR=4.3,CI=1.247-14.328, p=0.048).Conclusion: Beyond other routine examinations, SI is the only independent predictor ofin-hospital MACEs in NSTEMI patients presenting with heart failure.
Sistem Konduksi Jantung Ahmad Handayani
Buletin Farmatera Vol 2, No 3 (2017)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.695 KB) | DOI: 10.30596/bf.v2i3.1197

Abstract

Abstrak Pemahaman ilmu dasar kedokteran sangat penting bagi seorang klinisi. Aritmia merupakan masalah kardiovaskular yang cukup sering dijumpai dan menyulitkan. Pemahaman tentang dasar elektrofisiologi, cara kerja elektrokardiografi, dan mekanisme terjadinya aritmia jantung merupakan modal dasar seorang dokter untuk memiliki pendekatan yang logis dalam diagnosa dan terapi pada pasien dengan kondisi aritmia. Pemahaman sistem konduksi jantung setidaknya membutuhkan pemahaman tentang dua hal yakni dasar kelistrikan jantung mencakup potensial aksi sel otot jantung dan sel pacu jantung dan konsep pembentukan dan penjalaran impuls melalui sistem konduksi jantung. Tulisan ini bertujuan memberikan gambaran umum yang ringkas dan mendasar tentang sistem konduksi jantung. Kata kunci: aritmia, kelistrikan, konduksi, jantung  Abstract Understanding the basic science of medicine is very important for a clinician. Arrhythmias are a quite common and complicated cardiovascular problem. Understanding of the electrophysiological basis, the workings of electrocardiography, and the mechanism of cardiac arrhythmia are the doctors' basic requirement for having a logical approach to diagnosis and therapy in patients with arrhythmia. Understanding the cardiac conduction system requires at least an understanding of two things: the base of the heart's electricity includes the potential action of heart muscle and pacemaker cells and the concept of impulse formation and propagation through the cardiac conduction system. This paper aims to provide a concise and basic overview of the cardiac conduction system. Keywords: arrhythmia, electricity, conduction, heart
Premature Ventricular Complexes: Diagnose, Evaluation, and Management Ahmad Handayani; Anggia Chairuddin Lubis
Buletin Farmatera Vol 7, No 1 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i1.9684

Abstract

Premature ventricular complexes (PVCs) are arrhythmias due to abnormal impulse formation in the ventricles. The incidence is detected as much as 1% on standard electrocardiographic (ECG) examination. The aim of this literature review is to explain the diagnosis, evaluation, and management of PVC. The diagnosis of PVC is determined from the symptoms and evidence from the ECG recording. Symptoms may include a faster heartbeat sensation, chest discomfort, skipped beat, and intermittenly strong heartbeat. Evidence of PVC is established by regular ECG recordings or Holter. A 12-ECG can help determine the location of source. PVC evaluation includes determine the dangerousity, the next examination step, the treatment options, and whether ablation is needed. Managements include medical therapy and catheter ablation. Catheter ablation is performed where treatment is unsatisfactory or if the PVC causing life threathening arrhythmia or cardiomyopathy. PVC is considered dangerous if the underlying disease is found in the form of cardiac structural abnormalities, ischemic heart disease or other arrhythmic disorders, more than 2000 PVC is found in 24 hours, complex morphology, different morphology, increased with exercise, PVC with non-outflow tract form, with short coupling interval, and with a wider QRS duration The incidence of VVC that is considered to be able to induce cardiomyopathy is from 10-26%. PVC requires a structured and systematic diagnosis and evaluation step to determine the appropriate treatment.
HUBUNGAN POLIMORFISME GEN ANGIOTENSIN CONVERTING ENZYME DENGAN PERBAIKAN FRAKSI EJEKSI VENTRIKEL KIRI PADA PASIEN GAGAL JANTUNG KRONIK Ahmad Handayani; Isra Thristy; Meizly Andina
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.5549

Abstract

Latar Belakang:  Angiotensin  converting  enzyme (ACE)  adalah  enzim  yang  beredar  dan  membran  terikat dalam sistem renin-angiotensin. Polimorfisme  adalah  keberadaan  dua  atau  lebih  alel  pada  sebuah  lokus  dalam populasi. Pada penderita gagal jantung dengan gangguan fungsi sistolik maka sistem RAA ini teraktifasi. Salah satu terapi utama pada gagal jantung adalah pemberian obat penyekat angiotensin converting enzyme. Penelitian ini bertujuan melihat hubungan polimorfisme gen angiotensin converting enzyme dengan perbaikan fraksi ejeksi ventrikel kiri.  Metode : Penelitian  ini  merupakan  penelitian  eksperimental  yang  menggunakan  rancangan studi prospektif observasional yang dilakukan terhadap 37 pasien gagal jantung dengan penurunan fraksi ejeksi di Rumah Sakit Mitra Medika Bandar Klippa Deli Serdang. Setiap pasien diperiksa ekokardiografi awal dan minimal 1 bulan setelah pengobatan dimana telah terlihat perbaikan klinis. Seluruh pasien mendapatkan pengobatan sesuai standar pedoman tatalaksana gagal jantung kronik menurut ESC/ PERKI. Hasil : Mayoritas subyek penelitian adalah laki-laki sebanyak 81% dan rata-rata usia pasien adalah 56 tahun. Polimorfisme gen ACE didominasi oleh gen II sebanyak 57%. Nilai FEVK pada pengukuran pertama rerata adalah 25.8% dan pada pengukuran kedua meningkat menjadi 34.4%.  Terlihat perubahan signifikan antara pengukuran FEVK I sebesar rata-rata 25% menjadi 34% pada pengukuran berikutnya (p < 0.05). Pada analisis hubungan terlihat bahwa polimorfisme gen ACE tidak berpengaruh terhadap perbaikan nilai FEVK. Kesimpulan : Pengobatan gagal jantung kronik dengan penurunan fraksi ejeksi terlihat memberikan efek yang siginifkan dalam penignkatan FEVK. Tidak terdapat hubungan polimorfisme gen angiotensin converting enzyme terhadap respon terapi pasien gagal jantung kronik pada penelitian ini.
PREDICTORS OF IN-HOSPITAL LENGTH OF STAY IN NSTEMI PATIENTS Ahmad Handayani; Andika Sitepu; Faisal Habib
Buletin Farmatera Vol 4, No 3 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (734.521 KB) | DOI: 10.30596/bf.v4i3.2156

Abstract

As our population grows older, the rate of NSTEMI patients is rising. Risk stratification is an important process for patients with Non-ST Elevation Myocardial Infarction (NSTEMI). Global Registry of Acute Coronary Events (GRACE) scores in the best to predict mortality and myocardial infarction in NSTEMI Patients. On the other hand, NSTEMI Patients trends to be older with more co-morbidity. In this scenario, we need to predict the length of stay as it correlates with the patient's prognostic and cost. This study aims to analyze factors influencing the in-hospital length of stay in survivor NSTEMI Patients in four different hospitals (Adam Malik Medan National General Hospital, Pirngadi Medan General Hospital, Grandmed Lubuk Pakam General Hospital, and Aceh Tamiang Public General Hospital). This was an observational study with prospective design conducted on 44 patients in four different hospitals from March to May 2017. We only included the patients that discharged alive from the. hospital Statistical analysis was performed to assess the routine clinical and laboratory variables relations with the length of stay. Prolong length of stay was defined as more than 5 days. As mentioned in the previous study, older age, heart failure will prolong the length of stay. The limitations of this study were we didn't analyze the effect of revascularization, the co-morbidities, and the method of patient’s payment. We should use GRACE and TIMI risk score routinely, optimizing therapy for heart failure and giving special attention to elderly patients in NSTEMI Patients.Keywords: NSTEMI, GRACE, Length of Stay
FAKTOR RISIKO UTAMA YANG BERHUBUNGAN DENGAN KENDALI TEKANAN DARAH PADA POLISI PENDERITA HIPERTENSI LABUHAN BATU SELATAN ELIZABETH ADINDA PUTRI HARAHAP; AHMAD HANDAYANI
JURNAL ILMIAH MAKSITEK Vol 7 No 4 (2022): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Hypertension or high blood pressure is one of the diseases that contributes to the largest mortality in the world. Hypertension is characterized by high blood pressure in the systemic arteries. Blood pressure is expressed by systolic and diastolic blood pressure. According to the American Heart Association (AHA) hypertension has contributed to deaths globally around 10.4 million deaths annually and it is estimated that 1.39 billion people suffer from hypertension in 2010. There are several risk factors that cause hypertension, namely, gender, age, genetics, diet, exercise habits, obesity, alcohol consumption, excess salt consumption, smoking habits, work, stress, and comorbidities such as kidney disease and diabetes. One of the jobs that are at risk of developing hypertension is the police, where the police experience stress, the wrong diet, the wrong lifestyle. The objext of the research is To determine the main risk factors associated with the incidence of hypertension in South Labuhanbatu Police in 2021. This type of research is an analytic survey research with a cross sectional design. The sample used in the study amounted to 96 people. Data retrieval was carried out with primary data obtained by two methods, namely by conducting direct interviews by distributing questionnaires to South Labuhanbatu police personnel. Secondary data includes the number of members, member names, age of members and main duties. Then the data will be collected and analyzed. The results the research are From 96 samples, the relationship between hypertension and age was obtained p value = 0.001 and OR:0,088, Food high in salt p value = 0.018 and OR; 0,221, Family history p value = 0.715, Smoking p value = 0.932, Alcohol consumption p value = 0.902, Obesity p value = 0.379, Physical activity p value = 0.08 and OR : 3,509, Stress p value = 0.189. the conclussion if the research there is a relationship between age, physical activity, and hypertension and there is no relationship between family history or genetics, smoking, alcohol consumption, obesity, stress and hypertension. The risk factor which is the main risk factor associated with the incidence of hypertension in the South Labuhanbatu police in 2021 is physical activity
Co-Authors Abdullah Afif Siregar Andika Sitepu Anggia Chairuddin Lubis AZZUHRA PERMATA KHAIRA DINDA ETIKA SURY ELIZABETH ADINDA PUTRI HARAHAP Faisal Habib GARBIE SYAHLY AGUNG Isra Thristy Kaban, Kartika Kartika Kaban Marwan Nasri Meizly Andina Mukhtar, Zulfikri Nasri, Marwan Siregar, Abdullah Afif TRESNA ADI PRAYOGA WIRDANI FADHILA Yelly Nursakinah Zulfikri Mukhtar