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IDENTIFIKASI ZAT PEWARNA RHODAMIN B PADA TERASI DAN GULALI KAPAS DI KOTA MEDAN Prayoko, Herdianto; Thristy, Isra
JURNAL IBNU SINA BIOMEDIKA Vol 1, No 1 (2017)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (134.999 KB) | DOI: 10.30596/isb.v1i1.1117

Abstract

ABSTRAKLatar belakang : rhodamin B merupakan zat warna sintetik yang umum digunakan sebagai pewarna tekstil. Pada manusia rhodamin B dapat menyebabkan iritasi pada saluran pernapasan, iritasi kulit, iritasi pada mata, iritasi pada saluran pencernaan, keracunan, dan gangguan hati. Penelitian ini bertujuan untuk mengidentifikasi zat pewarna rhodamin B pada terasi dan gulali kapas yang beredar di Kota Medan. Metode : penelitian ini menggunakan metode kromatografi kertas dengan teknik purposif sampling. Pemeriksaan dilakukan di Dinas Kesehatan Provinsi Sumatera Utara UPT Laboratorium Kesehatan Daerah Medan. Hasil : pada penelitian ini didapati bahwa dari jumlah 10 sampel terasi dan 10 sampel gulali kapas yang diperiksa berdasarkan harga Rf, warna visual, dan lampu UV menunjukkan hasil yang negatif. Kesimpulan : sampel terasi dan gulali kapas yang diperiksa tidak mengandung rhodamin B.Kata kunci : terasi, gulali kapas, rhodamin B, kromatografi kertas ABSTRACTBackground : rhodamin B is synthetic colour substance commonly used as a textile dye. Rhodamin B can cause irritation of the respiratory tract, skin irritation, irritation of the eyes, irritation of the digestive tract, poisoning, and liver disorders. This research aims to identify the substance dyes rhodamin B in shrimp paste and cotton candy that is circulating in the city of Medan. Methods : this research using paper chromatography and using purposive sampling technique. The examination was conducted at Dinas Kesehatan Provinsi Sumatera Utara UPT Laboratorium Kesehatan Daerah Medan (North Sumatra Health Office UPT Health Laboratory Area terrain). Results : in this study found that the number of 10 samples of shrimp paste and 10 sample of cotton candy examined showed a negative result seen based on the price of the Rf, visual color and UV light. Conclusion : shrimp paste and cotton candy samples were examined did not contain rhodamin B.Keyword : cotton candy, shrimp paste, rhodamin B, paper chromatography
PERBANDINGAN KADAR HEMOGLOBIN SEBELUM DAN SAAT MENTRUASI PADA MAHASISWI FK UMSU Saleha, Imamah Maratu; Thristy, Isra
JURNAL IBNU SINA BIOMEDIKA Vol 2, No 2 (2018)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.004 KB) | DOI: 10.30596/isb.v2i2.2614

Abstract

AbstrakLatar Belakang. Menstruasi adalah perdarahan yang terjadi secara periodik dan siklik dari uterus, disertai pelepasan endometrium. Zat besi tersimpan dalam hemoglobin, kadar hemoglobin dapat dipengaruhi oleh perdarahan, seperti pada saat menstruasi yang dialami oleh wanita akan mengalami kehilangan darah rata-rata sebanyak 80 mL, dimana setiap kehilangan 40 ml darah akan kehilangan 1,6 mg zat besi. Hilangnya darah pada saat menstruasi berpotensi mengalami anemia. Tujuan. Tujuan pada penelitian ini untuk membandingkan kadar hemoglobin sebelum dan saat menstruasi. Metode. Penelitian ini bersifat analitik jenis studi kohort. Sampel penelitian adalah mahasiswi FK UMSU angkatan 2013 yang memenuhi kriteria inklusi. Data dianalisis menggunakan T Test Dependent. Hasil. Berdasarkan hasil T Test nilai p > 0,05 (p=0,244), hal ini berarti tidak terdapat perbedaan bermakna dari rata-rata kadar hemoglobin sebelum dan saat menstruasi. Kesimpulan. Tidak ada perbedaan yang bermakna pada kadar hemoglobin sebelum dan saat menstrusi.Kata kunci: Hemoglobin, Menstruasi
ASPERGILLUS FUMIGATUS PADA SPUTUM PENDERITA BATUK KRONIK MENGGUNAKAN METODE PCR DAN KULTUR Thristy, Isra; Siregar, Yahwardiah
Majalah Kedokteran Bandung Vol 48, No 2 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.224 KB) | DOI: 10.15395/mkb.v48n2.760

Abstract

Kecepatan tumbuh jamur yang bertambah pada manusia dapat terjadi akibat berbagai penggunaan obat-obatan, alat-alat kesehatan invasif, juga terdapat faktor predisposisi berupa penyakit kronik yang berat termasuk penyakit keganasan. Aspergilus fumigatus merupakan salah satu spesies jamur sistemik yang dapat menginfeksi manusia. Penggunaan polymerase chain reaction (PCR) untuk mendeteksi jamur merupakan diagnostik yang optimal. Tujuan penelitian ini adalah menganalisis Aspergillus fumigatus menggunakan PCR dan kultur pada sputum penderita batuk kronik. Penelitian ini menggunakan 51 sampel sputum penderita batuk kronik yang berasal dari Rumah Sakit Haji Adam Malik Medan, periode Mei 2012?Februari 2013 diteliti dengan metode deskriptif cross-sectional. Sputum diperiksa menggunakan metode PCR dan dilakukan kultur sebagai gold standard pemeriksaan jamur. Hasil penelitian dari 51 sampel didapatkan pemeriksaan PCR positif 35 sampel (69%) dan PCR negatif 16 sampel (31%). Pada hasil kultur dijumpai kultur positif 29 sampel (57%) dan kultur negatif 22 sampel (43%). Simpulan dari hasil penelitian ini adalah dari 51 sputum penderita batuk kronik ternyata 69% mengandung jamur Aspergillus fumigatus dan keadaan ini diperkuat dengan hasil kulturnya. Pemeriksaan PCR dapat dipergunakan sebagai salah satu pemeriksaan jamur yang cepat dan tepat. [MKB. 2016;48(2):78?83]Kata kunci: Aspergillus fumigatus, batuk kronis, kultur, PCRAspergillus Fumigatus in Sputum of Patients with Chronic Cough Using PCR and Culture MethodAbstractThe increasing prevalence of fungal growth in humans may occur as a result of the use of various drugs, invasive medical devices, and also the presence of predisposing factors like severe chronic diseases, including malignant disease. Aspergillus fumigatus is a systemic fungal species that can infect human beings. Polymerase chain reaction (PCR) is the most optimum diagnostic method to detect fungus. The purpose of this study was to analyze the presence of Aspergillus fumigatus by using PCR and culture method in sputum of patients with chronic cough.  The sample of this study consisted of sputum from 51 patients who visited Haji Adam Malik Hospital in Medan. The examination applied the cross-sectional descriptive method. Sputum was examined using PCR and culture as the gold standard fungal examination. The results from the 51 samples showed that positive PCR results (69%) were found in 35 patients and negative results were found in 16 patients (31%). The culture results showed that positive cultures were seen in 29 samples (57%) and negative cultures were found in 22 samples (49%).  it is concluded that from 51 patients with chronic cough sputum, 69%  turn out to have Aspergillus fumigatus fungus and this result is reinforced by the culture results. PCR can be used as a quick and precise inspection method for detecting fungus. [MKB. 2016;48(2):78?83]Key words: Aspergillus fumigatus, chronic cough, culture, PCR
Hubungan Obesitas Dengan Terjadinya Gangguan Pendengaran Sensorineural Rahmi Sibagariang; Muhammad Edy Syahputra Nasution; Siti Masliana Siregar; Isra Thristy
Jurnal Kesehatan Panrita Husada Vol 5 No 2 (2020)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (Stikes Panrita Husada Bulukumba)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37362/jkph.v5i2.373

Abstract

Obesity is an increase in total body fat, that is if found to be overweight > 20% in men and 25% in women due to fat. Increased obesity cannot beseparated from lifestyle, such as decreased physical activity. One complication that can be caused by obesity is hearing loss, especiallysensorineural hearing loss caused by microangiopathic abnormalities, especially in the inner ear. But the relationship of events between obesity withhearing loss is still often a debate, because there is no definite consensus. The purpose of this research determine the relationship of obesity with sensorineural hearing loss. This research is an analytic study by obtaining cross-sectional study, with data obtained from the assessment of bodyweight and height to see the status of the mass index, physical examination of the ear, and audiometric examination. Data analysis techniques using the chi square test statistics. Research result obtained relationship between obesity with sensorineural hearing loss as much as 49.09% and the highest degree of hearing loss is mild degrees as much as 27.07%. Research conclusions there is a significant relationship between obesity with sensorineural hearing loss. Keyword: Hearing Loss, Obesity, Obesity with Hearing Loss, Pure Tone Audiometry, Sensorineural Hearing Loss,
PERBANDINGAN KADAR GULA DARAH SEWAKTU DAN ASAM URAT PADA PENDERITA STROKE ISKEMIK DENGAN STROKE HEMORAGIK DI RUMAH SAKIT UMUM HAJI MEDAN PROVINSI SUMATERA UTARA TAHUN 2018 – 2019 ANDRE PRAMUDIA KRISNA; ISRA THRISTY
JURNAL ILMIAH MAKSITEK Vol 6 No 1 (2021): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Stroke is a major cause of death and disability in many countries. Risk factors for stroke include hypertension,hyperlipidemia, hyperuricemia, DM. Data on risk factors for stroke nationally are not yet known with certainty so that furtherresearch needs to be done. This study aims to determine the comparison of blood sugar levels and uric acid in patients withischemic and hemorrhagic strokes at Haji General Hospital Medan City in 2018-2019. This type of research is analyticdescriptive. The approach used in this study is retrospective. Data were processed using SPSS Mann-Whitney test.There was no significant difference in blood sugar levels between ischemic stroke and hemorrhagic stroke (p = 0.233). Therewas a significant difference in uric acid between ischemic stroke and hemorrhagic stroke (p = 0.00). There was no significantdifference in blood sugar levels between ischemic stroke and hemorrhagic stroke. While there are significant differences inuric acid levels between ischemic stroke and hemorrhagic stroke.
HUBUNGAN GANGGUAN ANSIETAS TERHADAP PENINGKATAN KADAR KOLESTEROL PADA PASIEN ANSIETAS YANG BEROBAT JALAN DI RSU MADANI MEDAN ELVIANI .; NANDA SARI NURALITA; ELMEIDA EFFENDY; ISRA THRISTY
JURNAL ILMIAH MAKSITEK Vol 6 No 2 (2021): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Anxiety is the most common psychiatric disorder. Overeating due to the response to anxiety disorders can cause an increasein total cholesterol and LDL levels. To determine the relationship between anxiety disorders and increased cholesterol levelsin anxiety patients who treatment at the RSU. Madani. This study use cross sectional study design. The sampling techniqueuse non-probability sampling. The examination was carried out using an easy-touch cholesterol level check tool.The number of samples used was 41 respondents with anxiety disorders, then an analysis test was performed using theKruskal-Wallis test. The Kruskal-Wallis test results showed that there is a relationship between anxiety disorders andincreased cholesterol levels in patients with anxiety disorders with a value of p = 0.001 (p <0.05). Anxiety disorders of asevere degree can raise cholesterol levels. There is a relationship between anxiety disorders and increased cholesterollevels in patients with anxiety disorders.
PERBANDINGAN EFEKTIVITAS JUS BUAH TOMAT (LYCOPERSICUM ESCULANTUM MILL.) DENGAN JUS BUAH JAMBU BIJI MERAH (PSIDIUM GUAJAVA L.) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL PADA TIKUS PUTIH JANTAN YANG DIINDUKSI KUNING TELUR MUHAMMAD AULIA RAHMAN; IRFAN HAMDANI; ISRA THRISTY; MUHAMMAD JALALUDDIN ASSUYUTHI CHALIL
JURNAL ILMIAH SIMANTEK Vol 3 No 3 (2019): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Communities have an unhealthy lifestyle that leads to an increase in total cholesterol levels. Tomato juice (Lycopersacum esculentum M.) and red guava (Psidium guajava L.) contain lycopene which is high enough of antioxidant that can lower blood cholesterol levels. Methods: This study was experimental using pretest posttest with control group design. White rat (Rattus norvegicus L.) male 24 wistar strain induced egg yolk 6.25gr / kgBW, grouped into 4, negative controls were given distilled water, positive control was given egg yolk, one treatment was given tomato juice 3 cc and two treatment was administered 3 cc red guava fruit juice for 2 weeks then blood was taking for 3 times, pretest, intervention and posttest. Result: the average of total cholesterol level posttest negative control group, positive control, one treatment and two treatment respectively 64,82 mg / dl, 78,48 mg / dl, 61,24 mg / dl, 41,81 mg / dl . ANOVA test results showed that there was a significant difference between posttest intervention of treatment group one and treatment group two with p = 0,021 and 0,000 (p <0,05). Conclusion: The provision of tomato juice and red guava juice can reduce total cholesterol levels of rats. Red Guava juice is more effective to lower total cholesterol of rats.
PERBANDINGAN EFEKTIVITAS EKSTRAK ETANOL DAUN AFRIKA (VERNONIA AMYGDALINA DEL.) DENGAN SIMVASTATIN TERHADAP KADAR HDL PADA TIKUS JANTAN GALUR WISTAR YANG DIINDUKSI KUNING TELUR YUFI YUWARDITRA; ISRA THRISTY
JURNAL ILMIAH SIMANTEK Vol 5 No 1 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Egg yolk is a food that contains a lot of lipids so that it can cause dyslipidemia which is characterized by a decrease in HighDensity Lipoprotein (HDL). In overcoming this, simvastatin are often used therapies. Indonesian people are starting to worryabout the side effects of treatment using chemicals. Using many traditional medicinal herbs. One type of plant used is Africanleaves (Vernonia amygdalina Del.). To study the interaction of African leaf ethanol extract (Vernonia amygdalina Del.) withsimvastatin on HDL levels in wistar strain male rats induced by egg yolk. This study was an experimental study with thePosttest method with a control group design. This study uses test animals male white rats Wistar (Rattus novergicus) whichwill be divided into 5 groups and using Oneway ANOVA test data analysis. From the results of data analysis, the averagevalue of HDL extract of African leaf ethanol obtained was 72.6; simvastatin 75,8 and a combination of ethanol extract ofAfrican leaves with simvastatin 81,6. Oneway ANOVA analysis showed (p <0.05). Giving ethanol extract of African leaves,simvastatin and Combination of extracts Ethanol leaves of Africa with simvastatin did not differ in increasing HDL levels ofmice.
KARAKTERISTIK PADA ANAK DOWN SINDROM DI SLB NEGRI PEMBINA MEDAN ADINDA .; ISRA THRISTY
JURNAL ILMIAH SIMANTEK Vol 5 No 4 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Down syndrome is a genetic disorder caused by chromosomal abrasion which causes the baby to have an excess of 1chromosome on chromosome 21, can be recognized by specific physical signs, IQ intelligence level is below normal andbelongs to the group of mental retardation. This type of research is quantitative descriptive with a cross sectional design,data collection is taken once, to determine the characteristics of children with Down syndrome at SLB E Negri PembinaMedan. The highest proportion of Down Syndrome children based on the sociodemography of Down Syndrome childrenaged 6-10 years (63%), based on male sex 11 people (40.7%), based on education level 27 elementary school students(100%), based on Most children diagnosed with Down syndrome were after birth as many as 25 people (92.6%), based onfamily ancestry without previous Down syndrome as many as 24 people (88.9%), Clinical symptoms that often appear inchildren with Down syndrome are slanted eyes, ears small and low position, short neck, short fingers and toes, 2 finger littlefinger, wide thumb and forefinger distance of 27 people (100%). Children with down syndrome are mostly affected by themale sex. male, aged 6-10 years, with elementary school education, many children with Down syndrome are diagnosed afterbirth, and do not have children in the family.
PERBANDINGAN KADAR LDL DAN HDL PADA PENDERITA STROKE ISKEMIK DENGAN STROKE HEMORAGIK DI RUMAH SAKIT UMUM HAJI KOTA MEDAN DESI ELISA FLOWER; ISRA THRISTY
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Stroke occurs in a blood vessel in the brain which is caused by a blockage and rupture of blood vessels in the brain.Broadly speaking, strokes are divided into two, including ischemic stroke and hemorrhagic stroke. Stoke is also closelyrelated to LDL and HDL levels, because LDL and HDL levels influence atherosclerosis which is part of the pathophysiologicalprocess of stroke. Comparing LDL and HDL levels in ischemic and hemorrhagic strokes in Medan Hajj General Hospital. Thestudy used secondary data, namely LDL and HDL levels in patients with ischemic and hemorrhagic strokes by collectingmedical records according to the determined sample size. The average of ischemic stroke patients was 43.85 mg / dl,hemorrhagic stroke patients had HDL levels of 41.07 mg / dl. LDL levels in ischemic stroke patients are 139.07 mg / dl andhemorrhagic stroke patients are 81.21 mg / dl. Based on the results of the study There is no comparison between HDL levelsin ischemic stroke patients and hemorrhagic patients, there is a comparison between LDL levels in ischemic stroke patientsand hemorrhagic patients.