Tendean, Hermie M M
Indonesian Socety of Obstetrics and Gynecology

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Maternal Serum Interleukin6 Level in Correlation with Preterm Delivery Noviyanti, Noviyanti; Tendean, Hermie M M; Kaeng, Juneke J
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.092 KB)

Abstract

Objective: To determine the correlation between maternal serum Interleukin-6 (IL-6) serum level with preterm delivery. Methods: We performed an observational cross-sectional study of 30 pregnant women between 21 to 36 week gestational age with and wthout labour (delivery) in Prof. Dr. RD. Kandou Hospital Manado. Samples were collected with consecutive sampling method. Data was analyzed using Mann-Whitney test with significance level of p
Hypoxia Inducible Factor1α in Correlation with Preeclampsia Juarsa, Hendrik; Tendean, Hermie M M; Wantania, John E
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 1, January 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (54.485 KB) | DOI: 10.32771/inajog.v4i1.67

Abstract

Objective: To know the correlation between Hypoxia Inducible Factor (HIF)-1α level with preeclampsia. Method: The study was conducted at the Obstetrics and Gynecology Department of Prof. Dr. R. D. Kandou Hospital. This research was carried out from April to June 2014. This study is a cross-sectional analytic approach in preeclampsia and normotensive pregnancy. We perform cubital venous blood sampling for inspection by 5 ml of serum and stored it in a refrigerator (-20°C). The level of HIF-1α serum was done by quantitative ELISA method in Prodia Lab Jakarta. Result: Seventy six pregnant women with 38 normotensive pregnancies and 38 preeclampsia, showed a significant association between the average levels of HIF-1α in the serum of pregnant women with preeclampsia compared to normotensive pregnancies (p = 0.000). Conclusion: There is a positive relationship between the levels of HIF-1α in serum of preeclampsia, in which HIF-1α levels in preeclampsia was higher than normotensive pregnancies. [Indones J Obstet Gynecol 2016; 1: 19-22] Keywords: hypoxia inducible factor-1α, preeclampsia
Maternal Serum Interleukin6 Level in Correlation with Preterm Delivery Noviyanti, Noviyanti; Tendean, Hermie M M; Kaeng, Juneke J
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.092 KB) | DOI: 10.32771/inajog.v3i4.52

Abstract

Objective: To determine the correlation between maternal serum Interleukin-6 (IL-6) serum level with preterm delivery. Methods: We performed an observational cross-sectional study of 30 pregnant women between 21 to 36 week gestational age with and wthout labour (delivery) in Prof. Dr. RD. Kandou Hospital Manado. Samples were collected with consecutive sampling method. Data was analyzed using Mann-Whitney test with significance level of p
Hypoxia Inducible Factor1α in Correlation with Preeclampsia Juarsa, Hendrik; Tendean, Hermie M M; Wantania, John E
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No. 1, January 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (54.485 KB) | DOI: 10.32771/inajog.v4i1.67

Abstract

Objective: To know the correlation between Hypoxia Inducible Factor (HIF)-1α level with preeclampsia. Method: The study was conducted at the Obstetrics and Gynecology Department of Prof. Dr. R. D. Kandou Hospital. This research was carried out from April to June 2014. This study is a cross-sectional analytic approach in preeclampsia and normotensive pregnancy. We perform cubital venous blood sampling for inspection by 5 ml of serum and stored it in a refrigerator (-20°C). The level of HIF-1α serum was done by quantitative ELISA method in Prodia Lab Jakarta. Result: Seventy six pregnant women with 38 normotensive pregnancies and 38 preeclampsia, showed a significant association between the average levels of HIF-1α in the serum of pregnant women with preeclampsia compared to normotensive pregnancies (p = 0.000). Conclusion: There is a positive relationship between the levels of HIF-1α in serum of preeclampsia, in which HIF-1α levels in preeclampsia was higher than normotensive pregnancies. [Indones J Obstet Gynecol 2016; 1: 19-22] Keywords: hypoxia inducible factor-1α, preeclampsia