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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) CHEMPUBLISH JOURNAL Jurnal Katalisator JIK- JURNAL ILMU KESEHATAN Jurnal Farmasi Higea Jurnal Medika Hutama Jurnal Inovasi Penelitian JAFP (Jurnal Akademi Farmasi Prayoga) Detector: Jurnal Inovasi Riset Ilmu Kesehatan Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan

Ifmaily, Ifmaily

Fakultas Farmasi Universitas Perintis Indonesia

Author-ID : 889760

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Pengaruh Ekstrak Kulit Buah Mangga Harum Manis (Mangifera indica L) terhadap Tekanan Darah pada Tikus Putih Jantan Hipertensi Ifmaily, Ifmaily
Jurnal Farmasi Sains dan Terapan Vol 6, No 2 (2019)
Publisher : Jurnal Farmasi Sains dan Terapan

Hypertension is the most common disease in Indonesia. The impact of hypertension can affect other organs such as the kidneys, heart, and eventually cause death. The prevalence of hypertension increases from year to year. One alternative treatment for hypertension is the use of natural ingredients that contain flavonoids. Mango (the leaves, fruit, fruit peel and stems) is one of the plants that can be used for anti-hypertension, because of its flavonoid content. Ethanol extract of leaves, fruit and stem of Mango already proved as an antihypertensive drug, but the peel of the fruit has not been studied, so far it has only been a waste. The purpose of this study was to determine the effect of varying doses of the extract of mango peel varieties Harum Manis (EKBMHM) on white male hypertensive rats. This study was experimental with a pretest-posttest control group design, using male white rats, divided into 6 groups: negative control group, positive control, treatment group 30 mg / kg BW, treatment group 60 mg / kg BW, treatment group 120 mg / kg BW and comparison group (amlodipine 5 mg / kgBW. Prednisone 1.5 mg / kgBW in 2.5% NaCl are used to induce hypertension in animal. The parameters used were blood pressure which measured using a Non-Invasive Blood Pressure. Data analysis was calculated using one-way ANOVA followed by Duncan's test. The results obtained showed a dose of 30 mg / kg BW and a dose of 120 mg / kg BW extract of mango peel cannot reduce blood pressure, while a dose of 60 mg / kg BW can reduce blood pressure in hypertensive rats where the results of blood pressure measurements are not significantly different with comparison group (amlodipine 5 mg / kg BW). The conclusion for this research,the administration of mango peel varieties Harum Manis extract at a dose of 60 mg / kg BW given to hypertensive rats shows potential as an antihypertensive drug (p value = 0.047).

Penetapan Kadar Pati PENETAPAN KADAR PATI PADA BUAH SUKUN (Artocarpus altilis L) MENGGUNAKAN METODE LUFF SCHOORL IFMAILY IFMAILY
CHEMPUBLISH JOURNAL Vol. 3 No. 1 (2018): Chempublish Journal
Publisher : Universitas Jambi, Fakultas Sains dan Teknologi, Program Studi Kimia

Zat penting dalam memenuhi kebutuhan gizi salah satunya amylum atau pati, sebagai sumber energi manusia di dunia, diperkirakan 80% bersumber dari pati. Industri bahan makanan di dunia saat ini, memproduksi pati berkisar 50 juta ton per tahun, dan laju pertumbuhan 7,7 % per tahun, dan perkembangan produksi pati dunia oleh industri makanan modern sudah merangsang berbagai pihak untuk mengidentifikasi polisakarida ini dari sumber baru ( Jong dan Adi, 2007:54 ). Kandungan pati ada pada beras, jagung, kacang, juga pada buah-buahan, salah satunya buah sukun. Penelitian bertujuan untuk menentukan kadar pati pada buah sukun (Artocorpus altilis L ) terkait dari jumlah, kadar, dan bentuknya. Pati merupakan bahan dasar di industri makanan atau bahan tambahan untuk pembuatan tablet di industri farmasi. Penetapan kadar dilakukan menggunakan metode Luff Schoorl. Hasil penelitian diperoleh rendemen pati buah sukun 7,167 % dari ekstrak, kadar air pada buah sukun sebesar 0,69 %, kadar abu pada sukun sebesar 0,45%. Filtrat dari pati buah sukun direaksikan dengan larutan Luff Schoorl lalu dilakukan pemanasan menggunakan pendingin tegak lalu dititrasi dengan Na2S2O3. Hasil dari penetapan kadar pati yang diperoleh dari buah sukun yaitu sebesar 71,67%, dengan bentuk pati bulat dan bulirnya tidak rapat.

Pelaksanaan Sistem Informasi Manajemen Rumah Sakit Pada Unit Rawat Jalan Rumah Sakit Dr. Reksodiwiryo Padang 2020 Randy Anugrah Pratama; Ifmaily Ifmaily; Erkadius Erkadius; Dian Paramitha Asyari
JIK-JURNAL ILMU KESEHATAN Vol 5, No 1 (2021): JIK-April Volume 5 Nomor 1 Tahun 2021
Publisher : STIKes ALIFAH PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33757/jik.v5i1.390

AbstrakKetersediaan data dan informasi kesehatan sangat penting dalam pengambilan keputusan di sebuah rumah sakit. Agar data dan informasi yang dihasilkan tepat, maka rumah sakit harus melaksanakan seluruh kegiatan pencatatan dan pelaporan yang dilakukan dalam bentuk Sistem Informasi Manajemen Rumah Sakit (SIMRS). Tujuan penelitian ini untuk melihat pelaksanaan SIMRS pada unit rawat jalan rumah sakit Dr. Reksodiwiryo Padang. Penelitian menggunakan pendekatan Kualitatif dengan metode Purpossive Sampling yang dilakukan di rumah sakit Dr. Reksodiwiryo Padang. Pengumpulan data dengan wawancara dengan 6 orang informan, observasi dan telaah dokumen. Hasil penelitian menjelaskan saat ini rumah sakit Dr. Reksodiwiryo Padang menggunakan aplikasi SIMRS Khanza dan telah terpasang serta terhubung dimasing-masing unit rawat jalan rumah sakit. Namun peran SIMRS hanya untuk mempermudah pelayanan dan perekapan data pasien saja dan belum digunakan untuk tingkat evaluasi manajemen. Secara umum dapat disimpulkan bahwa pelaksanaan SIMRS pada unit rawat jalan sudah terlaksana dan berjalan dengan baik namun hasil data dari SIMRS tersebut belum digunakan secara maksimal karena peran SIMRS hanya untuk mempermudah pelayanan saja.

EFEK GEL DAUN TEMU PUTIH (Curcuma zedoaria (Christm.) Roscoe) SEBAGAI ANTIINFLAMASI DENGAN METODA INDUKSI KARAGEN DAN KANTONG GRANULOMA PADA MENCIT PUTIH JANTAN Ifmaily Ifmaily; Suai Batul Islamiyah; Putri Rizki Fitriani
Jurnal Inovasi Penelitian Vol 1 No 10: Maret 2021
Publisher : Sekolah Tinggi Pariwisata Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47492/jip.v1i10.425

Ekstrak rimpang dan daun temu putih (Curcuma zedoaria (Christm.) Roscoe) pada penelitian sebelumnya mengandung khasiat sebagai analgesik, antiinflamasi, dan antikanker. Saat rimpang dipanen, maka daunnya menjadi limbah. Penelitian ini bertujuan untuk mengetahui efek gel ekstrak daun temu putih sebagai antiinflamasi terhadap mencit putih jantan dan pengaruh variasi konsentrasi gel ekstrak daun temu putih dengan parameter volume eksudat, total jumlah leukosit, dan jenis leukosit. Penelitian eksperimental murni, dengan tahapan proses ekstraksi daun temu putih, pembuatan formulasi gel ekstrak, penginduksian mencit dengan metode karagen dan kantong granuloma agar inflamasi, uji aktivitas antiinflmasi dari ekstrak daun temu putih, terakhir analisis data dengan ANOVA satu arah dilanjutkan uji Duncan. Hewan percobaan yang digunakan adalah mencit putih jantan sebanyak 25 ekor yang dikelompokkan menjadi 5 kelompok yaitu kelompok 1 kontrol negatif, kelompok 2,3,4 adalah gel ekstrak daun temu putih dengan konsentrasi 2,5%, 5%, dan 10% dan kelompok 5 sebagai pembanding yaitu gel Kaltrofen. Hasil penelitian berturut-turut yaitu pada kontrol negatif, gel ekstrak daun temu putih 2,5%, 5%, 10% dan pembanding ( gel Kaltrofen 2,5%) adalah sebagai berikut untuk volume eksudat mencit ( mL ); 0,69±0.01; 0,49±0,01; 0,40±0,00; 0,31±0,00, dan 0,30±0,01, untuk total leukosit (/μL) dari eksudat mencit adalah 13356±545; 9663±567; 8325±635; 6157±653; 6123±535, untuk jenis sel leukosit neutrofil segmen dan limfosit adalah yang dominan. Kesimpulannya adalah gel ekstrak daun temu putih dengan konsentrasi 2,5%, 5% dan 10% memberikan efek antiinflamasi. Pemberian gel ekstrak daun temu putih 2,5%, 5% dan 10% memberikan efek antiinflamasi setelah perlakuan pada hari ke-7 karena menurunkan volume eksudat, total leukosit dan jenis sel neutrophil segmen dan limfosit secara signifikan terhadap kelompok kontrol dengan (p<0,05)

THE EFFECT OF MANGO LEAVES EXTRACT VAR ARUM MANIS (Mangifera indica L.) AS IMUNOSTIMULANTS ON MICE MODEL Ifmaily Ifmaily; Putri Rizki Fitriani
Jurnal Inovasi Penelitian Vol 2 No 4: September 2021
Publisher : Sekolah Tinggi Pariwisata Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47492/jip.v1i4.834

Background : Every time our body is always exposed to microorganisms that can cause infection. Usually we are immune to infection because of the immune system that protects us, but when the body is exposed to antigens while the immune system activity decreases, then we need immunostimulants. One of traditional plant always get to use as the traditional drug is mango plant, Previous research it have effect as antioxidant, antidiabetes type II, antiinflammatory, anticancer, antihypertensive, and antimicrobial. It contains the flavonoid, alkaloid, phenolic,and steroid compounds. This study aims to determine the effect of mango leaves extract var arum manis against the activity and phagocytosis capacity of macrophage cells, and the percentage of leukocyte cell types, as well as the effect of dose variations on the administration of var arum manis mango leaves extract. Methods :Twenty mice were divided into 4 groups. Consisting of group I getting 0.5% Na.CMC, groups II, III and IV getting mango leaves extract var arum manis with consecutive doses of 30 mg / kgBW, 60 mg / kgBW, and 120 mg / kgBW which were given respectively. orally once a day for 7 days. On the eighth day, Staphylococcus aureus bacteria were injected intraperitoneally and after one hour, the activity and capacity of macrophage cell phagocytosis and the percentage of leukocyte cell types were calculated. Result and Discussion: The activity and phagocytosis capacity of macrophage cell was determined by calculating the phagocytosis index where the results obtained were the higher the dose, the increased activity and phagocytosis capacity of macrophage cell which affected the percentage of leukocyte cell types. The data were then processed by statistical analysis of one-way ANOVA. Conclusion of research showed that the mango leaves extract var arum manis at a dose of 30 mg / KgBW, 60 mg / KgBW, 120 mg / KgBW was significant (p ≤ 0.05) and affected activity and phagocytosis capacity of macrophage cells and the percentage of leukocyte cell types significantly (p ≤ 0.05), where the most effective result was a dose of 120 mg / KgBW

Studi Analisa Efektivitas Biaya pada Pasien Kanker Payudara yang Menjalani Kemoterapi di RSUP DR. M. Djamil Padang Rahmi Yosmar; Listia Ningsih; Ifmaily Ifmaily
Jurnal Farmasi Higea Vol 12, No 1 (2020)
Publisher : STIFARM Padang

Kanker payudara adalah keganasan pada jaringan payudara yang berasal dari epitel duktus maupun lobusnya. Salah satu pengobatan kanker payudara adalah kemoterapi. Tujuan dari penelitian ini untuk mengetahui efektivitas biaya regimen kemoterapi yang digunakan pasien kanker payudara di RSUP Dr. M Djamil Padang. Penelitian ini merupakan penelitian deskriptif dengan pendekatan retrospektif. Data diambil dari rekam medis dan administrasi pasien. Teknik sampling adalah Purposive Sampling. Parameter yang digunakan adalah peningkatan kesehatan pasien dan total biaya medis langsung. Pasien yang sesuai dengan kriteria inklusi berjumlah 64 pasien. Regimen kemoterapi yang digunakan adalah FAC; Gemcitabine+Navelbine; Paclitaxel+Cisplatin; Paclitaxel+ Doxorubicin; Docetaxel dan FAC+Herceptin. Regimen kemoterapi yang paling cost-effective untuk pasien kanker payudara stadium II adalah FAC, stadium III adalah FAC dan stadium IV adalah Paclitaxel+Doxorubicin.

IDENTIFIKASI DAN UJI RESISTENSI BAKTERI DARI SWAB (USAP) TENGGOROKAN PENYEBAB PNEUMONIA PADA PASIEN YANG DI RAWAT INAP BANGSAL PARU RSUP DR. M. DJAMIL PADANG Ringga Novelni; Ifmaily Ifmaily; Alamsyah Hanafiah
Jurnal Akademi Farmasi Prayoga Vol 5 No 2 (2020): Jurnal Akademi Farmasi Prayoga Vo.5 No.2 Tahun 2020
Publisher : Jurnal Akademi Farmasi Prayoga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1110.373 KB)

ABSTRAK Pneumonia merupakan salah satu masalah kesehatan penyebab kematian tertinggi. Penelitian ini dilakukan terhadap pasien pneumonia di Bangsal Paru RSUP Dr. M. Djamil Padang pada bulan Februari- April 2019. Jenis penelitian ini merupakan penelitian deskriptif eksploratif dengan desain prospektif. Identifikasi bakteri penyebab pneumonia dari swab tenggorokan 10 orang pasien pneumonia di Bangsal paru RSUP Dr. M. Djamil Padang diawali dengan isolasi bakteri dengan penanaman sampel pada media Agar Darah dan media Mac Conkey. Selanjutnya dilakukan identifikasi dengan pewarnaan gram dan uji biokimia. Dari hasil uji identifikasi bakteri didapatkan 7 jenis bakteri penyebab pneumonia, yaitu 1 kultur Enterobacter aerogenes (10%), 2 kultur Pseudomonas aeruginosa (20%), 3 kultur Klebsiella pneumoniae (30%), 1 kultur Staphylococcus aureus (10%), 1 kultur Streptococcus pneumoniae (10%), 1 kultur Staphylococcusepidermidis (10%), dan 1 kultur Proteus mirabilis (10%). Uji resistensi bakteri hasil isolasi dilakukan terhadap 5 antibiotik yaitu amoksisilin, cefotaxim, kloramfenikol, gentamisin dan eritromisin. Hasil uji resintensi bakteri didapatkan resistensi tertinggi terhadap antibiotik amoksisilin, sedangkan hasil sensitivitas tertinggi terhadap antibiotik gentamisin.

UJI AKTIVITAS EKSTRAK KULIT BATANG MANGGA ARUMANIS (Mangifera indica L) SEBAGAI ANTIHIPERTENSI PADA TIKUS PUTIH JANTAN DIINDUKSI NaCl 5% Ifmaily Ifmaily; Irwandi Irwandi; Siti Hajir; Aprilia Aprilia
Jurnal Inovasi Penelitian Vol 3 No 2: Juli 2022
Publisher : Sekolah Tinggi Pariwisata Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47492/jip.v3i2.1784

The part of arumanis mango plant (Mangifera indica L) is growing in Indonesia, a plant that has the potential to be a herbal medicinal plant because it contains secondary metabolites, one of which is a flavonoid which is useful as an antihypertensive. The purpose of this study was to determine whether the stembark extract of mango arummanis (Mangifera indica L) could affect blood pressure in hypertensive white male rats and to determine the variation in dosage of arummanis mango stembark extract (Mangifera indica L) which had an antihypertensive effect on hypertensive white male rats. In these research there was 24 white male rats was divided 6 groups insist of negative control, positive control, dosages groups ( 60, 120, 180 ) mg/kgBW and comparison group (Captopril 25 mg). Inducer was NaCl 5 %. Blood pressure measurements were performed using the (Non Invasive Blood Pressure) NIBP CODA tool. Data analysis used one-way ANOVA followed by the Duncan test, and the results showed that there were significant differences in systolic and diastolic blood pressure in the test group with (p<0.05). In conclusion, the extract of arummanis mango stembark (Mangifera indica L) can affect blood pressure in hypertensive white male rats with the best effect of antihypertensive at a dose of 180 mg /kgBW.

THE ANTIBACTERIAL MOUTHWASH OF TAPAK LIMAN LEAVES EXTRACT ( Elephanthopus scaber L ) AGAINST Streptococcus mutans IFMAILY IFMAILY
Jurnal Medika Hutama Vol. 1 No. 02 Januari (2020): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (818.055 KB)

Biodiversity Indonesia has been widely used as a treatment for Indonesian people. One of them is a plant of Tapak liman that efficacious antibacterial. The purpose of this research to know the formulation of the leaf extract of Tapak Liman which can be made as a antiseptic mouthwash and know the inhibiting power test of the leaf extract of the Tapak Liman against Streptococcus mutans. Streptococcus mutans can make the extra-cell polysaccharide consists mainly of a glucose polymer that forms a plaque matrix and can stick on the surface of the tooth causing plaque buildup and bad breath. This research was purely experimental by made the Tapak Liman leaves into a viscous extract, then it was made as the antiseptic mouthwash and testing of its inhibiting power against Streptococcus mutans. The antiseptic mouthwash of leaf extract of Tapak Liman is made into five formulas consist of F0 (base), F1 ( 10% ), F2 ( 20% ), F3 ( 30% ) and Fp as comparator ( Betadin mouthwash ). The antibacterial activity test of the antiseptic mouthwash of Tapak Liman with the diffusion method using the Nutrient Agar media (NA) and data was analyzed by One Way ANOVA. The result of research that the leaf extract of Tapak Liman in 3 concentrations variance can be formulated into the antiseptic mouthwash. The antiseptic mouthwash provides an average diameter – the average resistance of the barrier is F0 (8.40 mm), F1 (12.40 mm), F2 (12.80 mm) and F3 (13.60 mm) and Fp (14.80 mm). Conclusion of research that all of the formula leaf extract of Tapak Liman can be made as the antiseptic mouthwash, and all formulas that give inhibiting power test against the Streptococcus mutans

Pemanfaatan Gel Ekstrak Kulit Buah Mangga Arumanis (Mangifera indica L.) Sebagai Antiinflamasi Dengan Metode Kantong Granuloma Secara In-Vivo Ifmaily Ifmaily; Hastri Delfa Yenti; Meta Emillia Surya Dharma
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 1 No. 3 (2023): Agustus : Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Politeknik Pratama Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v1i3.2236

In previous research, mango rind extract has been studied as an antioxidant, antihypertensive, and antidiabetic, because it contains flavonoids and 17% mangiferin compounds. In this research, the effect of arumanis mango rind extract gel (Mangifera indica L.) as an anti-inflammatory was tested in male white mice induced by carrageenan using the granuloma pouch method. This experimental study used experimental white male mice which were grouped into 5 groups: the control group, the group with 2% mango rinf extract, the group with 4% mango rind extract, the group with 8% mango rind extract, and the comparison group. The parameters that were analyzed were exudate volume, total leukocytes, and type of leukocytes on days 3, 5, 7. The results showed that mango arumanis (Mangifera indica L.) rind extract had anti-inflammatory effectiveness topically as indicated by a decrease in the average exudate volume, total leukocytes, and leukocyte cell types (segmented neutrophil cells and lymphocyte cells) in each concentration group of mango rind extract, based on two-way ANOVA test and Duncan's test showed significant differences with respect to concentration and time (p<0.05). It can be concluded that all gel concentrations of arumanis mango rind extract (Mangifera indica L.) 2%, 4%, and 8% have anti-inflammatory effects.

Co-Authors Alamsyah Hanafiah Aprilia Aprilia Dian Paramitha Asyari Erkadius Erkadius Hastri Delfa Yenti Irwandi Irwandi Listia Ningsih Meta Emillia Surya Dharma Putri Rizki Fitriani Putri Rizki Fitriani Putri Rizki Fitriani Rahmi Yosmar Randy Anugrah Pratama Ringga Novelni Siti Hajir Suai Batul Islamiyah Ulfa Anggraini

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