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The Risk of Infection Human Papilloma Virus Infection in Acceptors of Depot Medroxyprogesterone Acetate Contraceptions Aras, Baharuddin; Tahir, Mardiah; Arifuddin, Sharvianty; Hartono, Eddy; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: Cervical cancer is the second most prevalent cancer inwomen around the world and the most common cancer in womencausing death. This study aims to analyze the connection betweeninfection of human papilloma virus (HPV) 16/18 and cervicalchanges in the acceptors of Depot Medroxyprogesterone Acetate(DMPA) Contraceptions and nonacceptors of Depot MedroxyprogesteroneAcetate (DMPA) Contraceptions.Methods: The research was conducted at the Public ServiceInstitution of Dr. Wahidin Sudirohusodo hospital, and privatemidwife clinics for seven months from December 2015 to June 2016.The research design is cross-sectional with. The samples were fortyacceptors of Depot Medroxyprogesterone Acetate (DMPA) and fortynon-acceptors of Depot Medroxyprogesterone Acetate (DMPA)contraception. Prevalence of HPV 16/18 and cervical cytologychanges were examine using the polymerase chain reaction andliquid base cervical cytology.Results: The results showed there was no significant relationshipbetween long-term use of DMPA contraceptives with HPV 16 and 18.There was no significant relationship between long-term use ofDMPA contraceptives with cervical cytology changes. There was nosignificant relationship between HPV 16 and 18 infections with theoccurrence of cervical cytology changes in long-term use of DMPAcontraceptives.Conclusion: The long-term use of DMPA contraceptive does notincrease the risk of HPV 16 and 18 infections. Also does not causecervical cytology changes that lead to cervical malignancy.Keywords: cervical cytology changes, Depot MedroxyprogesteroneAcetate (DMPA) contraception, HPV 16/18 infection

Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery Nurdin, Azizah; Irianta, Trika; Tahir, Mardiah; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the obstetric risk factors of the analincontinence in mothers with previous history of vaginaldelivery.Methods: The was a case-control study conducted in the Obstetricsand Gynecology Department of Dr.Wahidin Sudirohusodo Hospital,Faculty of Medicine, Universitas Hasanuddin, Makassar, during theperiod of February 2015 through January 2016. The researchinstruments were used to evaluate obstetric risk factors and theanal incontinence was the self-administered questionnaire and FecalIncontinence Severity Index. The data were analyzed statisticallyusing the Chi-square test with the significant value of p<0.05.Results: A total of 300 subjects were recruited in this study. Theresearch results indicated that the parity of  3, the assisted vaginaldelivery history (vacuum extraction), and the prolong secondstage of labor had a significant correlation with the anal incontinencewith p value=0.026, OR (95% CI) = 1.8 (1.07-3.03), p=0.018with OR (95% CI) =3.65 (1.2-10.7) and p=0.006 with OR (95% CI)= 2.9 (1.2-6.7).The history of episiotomy and the delivery of thebaby  4000 gram had no correlation with the anal incontinence.Conclusion: Parity, vacuum delivery and prolong second stage oflabor have an association with anal incontinence among womenwho has history of vaginal delivery.Keywords: anal incontinence, obstetric risk factors, vaginal delivery

Hypertriglyceridemia is associated with the incidence of preeclampsia Dahlan, Intje S; Tahir, Mardiah; Lukas, Efendi; T Chalid, St. Maisuri
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Objective: to find out  the correlation between lipid profille at trimester II of pregnancy and the incidence.of preeclampsia Method : The research  was conducted in the Polyclinic of Hasanuddin University Teaching Hospital, Department of Obstetrics and Gynecology of the Faculty of Medicine, and it network in Makassar city from March, 2015 through March, 2016. The research used was the prospective cohort design. Results : The examination of the lipid levels of 115 pregnant mothers, aged 24-28 weeks. The mothers were then observed whether they experienced preeclampsia up to the time they gave birth or not. In the end, 8 subjects (6.9%) experienced preeclampsia and 107 subjects (93.1%) have no preeclampsia. The statistical analyses used Fisher’s Exact test and Mann Whitney test. The research results indicated that the mean value of the total cholesterol and Low Density Lipoprotein (LDL) was higher in the preeclampsia group compared to the non-preeclampsia group: 267.37 ± 64.12 : 238 ± 37.98; 177.38 ± 55.38 : 157.24 ± 35.08 (p>0.05). The mean value of High Density Lipoprotein (HDL) was lower in the preeclampsia group compared to the non-preeclampsia group: 64.75 ± 14.64 : 67.86 ± 16.72 (p>0,05). The mean value of trigliserida in preeclampsia group was significantly higher (19,5%) compared thanin the non-preeclampsia group: 260.12 ± 58.86 vs 209.14 ± 65.10 (p=0,027). Conclusion : The hypertrigliseridemia was correlated with the preeclampsia incidence. Keywords:preeclampsia, lipid profile, trimester II of pregnancy   Abstrak Tujuan: mengetahui hubungan antara profil lipid kehamilan trimester II dengan kejadian preeklamsia. Metode : Penelitian dilaksanakan di Poliklinik RS jejaring pendidikan Departemen Obstetri dan Ginekologi Fakulltas Kedokteran Universitas Hasanuddin dan Poliklinik Kesehatan Ibu dan Anak di beberapa Puskesmas Kota Makassar selama Maret 2015 sampai dengan Maret 2016. Rancangan penelitian yang digunakan adalah prospektif  kohort. Hasil: dari 115 ibu hamil dilakukan pemeriksaan  kadar lipid, 115 ibu hamil pada usia kehamilan 24 – 28 minggu, kemudian diamati apakah subyek mengalami preeklamsia hingga proses persalinan. Terdapat delapan subyek (6,9%) berkembang menjadi preeklampsia dan 107 subyek tidak preeklamsia. Data dianalisis secara statistik dengan menggunakan uji Fisher’s Exact dan uji Mann Whitney. Hasil penelitian menunjukkan bahwa nilai mean kolesterol total dan Low Density Lipoprotein (LDL) lebih tinggi pada kelompok preeklampsia dibandingkan kelompok tidak preeklamsia, yaitu 267,37 ± 64,12 : 238,01 ± 37,98; 177,38 ± 55,38 : 157,24 ± 35,08 (p>0,05). Nilai mean High Density Lipoprotein (HDL) lebih rendah pada kelompok preeklamsia dibandingkan tidak preeklamsia yaitu 64,75 ± 14,64 : 67,86 ± 16,72 (p>0,05). Nilai mean trigli seri daripada kelompok preeklamsia secara signifikan lebih tinggi 19,5 % dibandingkan kelompok tidak preeklamsia, yaitu 260,12 ± 58,86 : 209,14 ± 65,10 (p=0,027). Kesimpulan : Hiper trigli seridemia berhubungan dengan kejadian preeklamsia. Kata kunci : preeklamsia, profil lipid, kehamilan trimester II    

Human Papilloma Virus16 and 18 Infection and the Cervical Cytology Changes in Combined Hormonal Contraceptive Users Darkuthni, Merdyana; Tahir, Mardiah; Tumedia, Josephine L
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

    Objective: To evaluate the correlation between HPV-16 and 18infection and the cervical cytology changes among combinationhormonal contraceptives users.   Methods: A cross-sectional study involved 40 women usingcombined hormonal contraceptive (oral or injection/DMPA contraceptive)and 40 women of non-hormonal contraceptive users wasconducted in Dr. Wahidin Sudirohusodo hospital, some affiliatedhospitals of Department of Obstetrics and Gynecology Faculty ofMedicine, Universitas Hasanuddin and a private clinic in Makassarfrom November 2015 and April 2016. HPV 16 and 18 genotypingin cervix using PCR method and cervical cytology changes usingliquid-based cytology (LBC) method were performed. HPV infectionand cervical cytology changes were analysis based on Fisher’s testand chi-square test.   Results: A significant difference found only in parity (p<0.05)between users and control of baseline characteristics. Neither usersnor control were significantly associated with HPV-16 and 18infection and changes in cervical cytology.   Conclusion: Combined hormonal contraceptives are not correlatedwith HPV-16 and 18 infection and changes in cervical cytology. Keywords: cervix, combined hormonal contraceptive, human papillomavirus

Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery Nurdin, Azizah; Irianta, Trika; Tahir, Mardiah; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the obstetric risk factors of the analincontinence in mothers with previous history of vaginaldelivery.Methods: The was a case-control study conducted in the Obstetricsand Gynecology Department of Dr.Wahidin Sudirohusodo Hospital,Faculty of Medicine, Universitas Hasanuddin, Makassar, during theperiod of February 2015 through January 2016. The researchinstruments were used to evaluate obstetric risk factors and theanal incontinence was the self-administered questionnaire and FecalIncontinence Severity Index. The data were analyzed statisticallyusing the Chi-square test with the significant value of p<0.05.Results: A total of 300 subjects were recruited in this study. Theresearch results indicated that the parity of  3, the assisted vaginaldelivery history (vacuum extraction), and the prolong secondstage of labor had a significant correlation with the anal incontinencewith p value=0.026, OR (95% CI) = 1.8 (1.07-3.03), p=0.018with OR (95% CI) =3.65 (1.2-10.7) and p=0.006 with OR (95% CI)= 2.9 (1.2-6.7).The history of episiotomy and the delivery of thebaby  4000 gram had no correlation with the anal incontinence.Conclusion: Parity, vacuum delivery and prolong second stage oflabor have an association with anal incontinence among womenwho has history of vaginal delivery.Keywords: anal incontinence, obstetric risk factors, vaginal delivery

The Risk of Infection Human Papilloma Virus Infection in Acceptors of Depot Medroxyprogesterone Acetate Contraceptions Aras, Baharuddin; Tahir, Mardiah; Arifuddin, Sharvianty; Hartono, Eddy; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: Cervical cancer is the second most prevalent cancer inwomen around the world and the most common cancer in womencausing death. This study aims to analyze the connection betweeninfection of human papilloma virus (HPV) 16/18 and cervicalchanges in the acceptors of Depot Medroxyprogesterone Acetate(DMPA) Contraceptions and nonacceptors of Depot MedroxyprogesteroneAcetate (DMPA) Contraceptions.Methods: The research was conducted at the Public ServiceInstitution of Dr. Wahidin Sudirohusodo hospital, and privatemidwife clinics for seven months from December 2015 to June 2016.The research design is cross-sectional with. The samples were fortyacceptors of Depot Medroxyprogesterone Acetate (DMPA) and fortynon-acceptors of Depot Medroxyprogesterone Acetate (DMPA)contraception. Prevalence of HPV 16/18 and cervical cytologychanges were examine using the polymerase chain reaction andliquid base cervical cytology.Results: The results showed there was no significant relationshipbetween long-term use of DMPA contraceptives with HPV 16 and 18.There was no significant relationship between long-term use ofDMPA contraceptives with cervical cytology changes. There was nosignificant relationship between HPV 16 and 18 infections with theoccurrence of cervical cytology changes in long-term use of DMPAcontraceptives.Conclusion: The long-term use of DMPA contraceptive does notincrease the risk of HPV 16 and 18 infections. Also does not causecervical cytology changes that lead to cervical malignancy.Keywords: cervical cytology changes, Depot MedroxyprogesteroneAcetate (DMPA) contraception, HPV 16/18 infection

Human Papilloma Virus16 and 18 Infection and the Cervical Cytology Changes in Combined Hormonal Contraceptive Users Darkuthni, Merdyana; Tahir, Mardiah; Tumedia, Josephine L
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

    Objective: To evaluate the correlation between HPV-16 and 18infection and the cervical cytology changes among combinationhormonal contraceptives users.   Methods: A cross-sectional study involved 40 women usingcombined hormonal contraceptive (oral or injection/DMPA contraceptive)and 40 women of non-hormonal contraceptive users wasconducted in Dr. Wahidin Sudirohusodo hospital, some affiliatedhospitals of Department of Obstetrics and Gynecology Faculty ofMedicine, Universitas Hasanuddin and a private clinic in Makassarfrom November 2015 and April 2016. HPV 16 and 18 genotypingin cervix using PCR method and cervical cytology changes usingliquid-based cytology (LBC) method were performed. HPV infectionand cervical cytology changes were analysis based on Fisher’s testand chi-square test.   Results: A significant difference found only in parity (p<0.05)between users and control of baseline characteristics. Neither usersnor control were significantly associated with HPV-16 and 18infection and changes in cervical cytology.   Conclusion: Combined hormonal contraceptives are not correlatedwith HPV-16 and 18 infection and changes in cervical cytology. Keywords: cervix, combined hormonal contraceptive, human papillomavirus

Hypertriglyceridemia is associated with the incidence of preeclampsia Dahlan, Intje S; Tahir, Mardiah; Lukas, Efendi; T Chalid, St. Maisuri
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Abstract Objective: to find out  the correlation between lipid profille at trimester II of pregnancy and the incidence.of preeclampsia Method : The research  was conducted in the Polyclinic of Hasanuddin University Teaching Hospital, Department of Obstetrics and Gynecology of the Faculty of Medicine, and it network in Makassar city from March, 2015 through March, 2016. The research used was the prospective cohort design. Results : The examination of the lipid levels of 115 pregnant mothers, aged 24-28 weeks. The mothers were then observed whether they experienced preeclampsia up to the time they gave birth or not. In the end, 8 subjects (6.9%) experienced preeclampsia and 107 subjects (93.1%) have no preeclampsia. The statistical analyses used Fisher’s Exact test and Mann Whitney test. The research results indicated that the mean value of the total cholesterol and Low Density Lipoprotein (LDL) was higher in the preeclampsia group compared to the non-preeclampsia group: 267.37 ± 64.12 : 238 ± 37.98; 177.38 ± 55.38 : 157.24 ± 35.08 (p>0.05). The mean value of High Density Lipoprotein (HDL) was lower in the preeclampsia group compared to the non-preeclampsia group: 64.75 ± 14.64 : 67.86 ± 16.72 (p>0,05). The mean value of trigliserida in preeclampsia group was significantly higher (19,5%) compared thanin the non-preeclampsia group: 260.12 ± 58.86 vs 209.14 ± 65.10 (p=0,027). Conclusion : The hypertrigliseridemia was correlated with the preeclampsia incidence. Keywords:preeclampsia, lipid profile, trimester II of pregnancy   Abstrak Tujuan: mengetahui hubungan antara profil lipid kehamilan trimester II dengan kejadian preeklamsia. Metode : Penelitian dilaksanakan di Poliklinik RS jejaring pendidikan Departemen Obstetri dan Ginekologi Fakulltas Kedokteran Universitas Hasanuddin dan Poliklinik Kesehatan Ibu dan Anak di beberapa Puskesmas Kota Makassar selama Maret 2015 sampai dengan Maret 2016. Rancangan penelitian yang digunakan adalah prospektif  kohort. Hasil: dari 115 ibu hamil dilakukan pemeriksaan  kadar lipid, 115 ibu hamil pada usia kehamilan 24 – 28 minggu, kemudian diamati apakah subyek mengalami preeklamsia hingga proses persalinan. Terdapat delapan subyek (6,9%) berkembang menjadi preeklampsia dan 107 subyek tidak preeklamsia. Data dianalisis secara statistik dengan menggunakan uji Fisher’s Exact dan uji Mann Whitney. Hasil penelitian menunjukkan bahwa nilai mean kolesterol total dan Low Density Lipoprotein (LDL) lebih tinggi pada kelompok preeklampsia dibandingkan kelompok tidak preeklamsia, yaitu 267,37 ± 64,12 : 238,01 ± 37,98; 177,38 ± 55,38 : 157,24 ± 35,08 (p>0,05). Nilai mean High Density Lipoprotein (HDL) lebih rendah pada kelompok preeklamsia dibandingkan tidak preeklamsia yaitu 64,75 ± 14,64 : 67,86 ± 16,72 (p>0,05). Nilai mean trigli seri daripada kelompok preeklamsia secara signifikan lebih tinggi 19,5 % dibandingkan kelompok tidak preeklamsia, yaitu 260,12 ± 58,86 : 209,14 ± 65,10 (p=0,027). Kesimpulan : Hiper trigli seridemia berhubungan dengan kejadian preeklamsia. Kata kunci : preeklamsia, profil lipid, kehamilan trimester II    

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