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Characteristics of The Patients with Low Back Pain in The Medical Rehabilitation Clinic, Dr. Ramelan Naval Hospital Surabaya Wijayaningrum, Lena; Setianingsih, Herin; Rahayu, Agustin Silfi
Oceana Biomedicina Journal Vol 2, No 2 (2019): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Background : The total number of visits of patients with complaints of low back pain in the Medical Rehabilitation Subdepartment of dr. Ramelan Naval Hospital Surabaya from January to November 2018 was 38.7% of all visits. Low back pain is a symptom, not a disease, which is defined as pain between the edge of the ribs and the gluteus fold which can be caused by a variety of causes. It is important to know how the characteristics of LBP sufferers.Material and Methods : This study was a descriptive study, Medical records from the LBP population in July to September 2018 are used, at the Dr. Ramelan Hospital RSAL Medical Rehabilitation Clinic, with sample criteria: There are main symptoms of pain or other unpleasant feelings in the lower spine and surrounding areas. Results : 152 data were analyzed from July to September 2018, patients with pain complaints were (86.84%). The data obtained showed patients with hypertensive comorbidities 30, Diabetes Mellitus 26, and Osteoarthritis 20.Conclusion : Characteristics of patients diagnosed with Low Back Pain (LBP) at the RSAL Medical Rehabilitation Clinic Dr. Ramelan Surabaya is aged 51-60 years, many suffer from women, 80 percent complain of pain, accompanied by hypertensive comorbidities, Diabetes Melitus and Osteoarthritis. Keywords : Low back pain (LBP), pain, comorbidities

Pengaruh Pemberian Oksigen Hiperbarik terhadap Kadar LDL Tikus Putih (Rattus norvegicus) Galur Sprague dawley yang kemudian Diberi Diet Tinggi Lemak Putri, Ika Apriyanti Arum; Setianingsih, Herin
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 8, No 1 (2019): EDISI MARET 2019 (available online since April 2019)
Publisher : Universitas Wijaya Kusuma Surabaya

Menurut WHO (2017), dari seluruh kematian akibat penyakit kardiovaskular 7,4 juta (42,3%) di antaranya disebabkan oleh Penyakit Jantung Koroner (PJK). Lipid, khususnya low density lipoprotein (LDL) merupakan salah satu faktor penting penyebab terjadinya PJK, mengingat perannya dalam proses aterogenesis. Terapi Oksigen Hiperbarik diketahui dapat menurunkan faktor resiko atherosklerosis seperti hiperkolesterolemia pada tekanan 1,5 ATA dan 3 ATA. Hiperkolesterolemia ini ditandai dengan peningkatan pada trigliserida (TG), LDL, dan penurunan HDL. Penelitian ini bertujuan untuk mengetahui pengaruh terapi oksigen hiperbarik terhadap kadar LDL tikus putih (Rattus norvegicus) galur Sprague dawley yang kemudian diberi diet tinggi lemak. Penelitian ini adalah penelitian eksperimental murni laboratoris. Subjek pada penelitian ini adalah 32 tikus putih (Rattus norvegicus) galur Sprague dawley yang dibagi menjadi dua kelompok yakni kelompok kontrol dan perlakuan. Kelompok kontrol diberikan diet tinggi lemak selama 49 hari dan kelompok perlakuan yang diterapi oksigen hiperbarik dengan kadar oksigen 98% tekanan 2,4 ATA selama 10 hari kemudian diberi diet tinggi lemak selama 49 hari. Hasil penelitian didapatkan rata-rata LDL kelompok kontrol sebesar 63,43 mg/dl dan kelompok perlakuan adalah 44,43 mg/dl. Kemudian, dilakukan uji hipotesa menggunakan metode Mann Whitney dan didapatkan nilai signifikansi (p) adalah 0,004 atau p<? sehingga dapat ditarik kesimpulan bahwa pada penelitian ini ada perbedaan kadar LDL darah tikus pada kedua kelompok perlakuan atau H1 diterima. Terapi oksigen hiperbarik berpengaruh terhadap penurunan kadar LDL darah pada tikus putih (Rattus norvegicus) galur Sprague dawley sebelum diberi diet tinggi lemak.

The Effect of Golden Sea Cucumber (Stichopus hermanii) Extracts to Serum LDL Cholesterol level as a Result of Insulin Resistence Herin Setianingsih; Fatima Sari Suryono Putri; Wahyu Prasasti Mutia Desi; Erlina Yatnasari
Indonesian Journal of Medical Sciences and Public Health Vol 1 No 1 (2020)
Publisher : Future Science

ABSTRACT Diabetes mellitus is a metabolic disease characterized by conditions of hyperglycemia as a result of abnormalities in the secretion of the insulin hormone, the work of the insulin hormone, or both. Metabolic disorders caused by diabetes cause lipolysis to increase, thereby increasing the level of VLDL, which will be converted to LDL. LDL disorders are the effects of insulin resistance. Streptozotocin (STZ) can increase serum LDL cholesterol serum levels due to the mechanism of ROS formation. Golden sea cucumber act as anti-hyperlipidemic because they contain EPA-DHA, saponins, and flavonoids. The purpose of these studies to determine the effect of Golden sea cucumber act as anti-hyperlipidemic. Experimental laboratory research is done using the post-test only control group design method. Using simple random sampling with 25 white male Wistar rats divided into five groups, all rats were given standard feeding. Group 1 without STZ induced, group 2-5 were induced STZ first, and then group 3-5 were given golden sea cucumber extract for 21 days with dose 4,25 mg/kg BW, 8,5 mg/kg BW, 12,75 mg/kg BW, per day respectively. At the end of the study, the LDL serum level was measured. The result of One – Way Anova test showed LDL cholesterol serum levels of group rats with STZ induction and given 12,75 mg/kg BW golden sea cucumber extracts (x=7,4 mg/dl) significantly decreased (p=0,005) compared to LDL cholesterol levels of group rats which were only induced by STZ without given golden sea cucumber extracts (x=12,6 mg/dl). This research showed that the administration 12,75mg/kg BW of golden sea cucumber extracts for 21 days reduced serum LDL cholesterol levels because golden sea cucumber contains compounds that work as antioxidants.

PENGARUH PEMBERIAN CUKA APEL (Malus sylvestris Mill) VARIETAS MANALAGI TERHADAP KADAR TRIGLISERIDA DARAH TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIBERI DIET TINGGI LEMAK DAN DIINDUKSI ALOKSAN Yuliyanti Yuliyanti; A. Sareh Arjono Tjandra; Herin Setianingsih
JURNAL AGRI-TEK : Jurnal Penelitian Ilmu-Ilmu Eksakta Vol. 20 No. 2 (2019): JURNAL AGRITEK
Publisher : Universitas Merdeka Madiun

Hypertriglyceridemia is one of the risk factors for cardiovascular disease and acute pancreatitis (Pejic and Lee, 2006; Brahm and Hegele, 2013; Afari et al., 2015). One way to treat it by using the apple vinegar (Malus sylvestris Mill) of manalagi varieties which contained high antioxidants and acetic acid as well as more durable than the fresh fruit. The study aimed to know the effect of the Apple vinegar of manalagi varieties (Malus sylvestris Mill) to blood triglyceride levels of white male rats (Rattus norvegicus) wistar strain with high-fat diet and induced by alloxan. The study used the post test only control group design, with 24 rats samples which were divided into three groups. The negative control group (K0) only received standard diet for 24 days, the positive control group (K1) received a high-fat diet for 7 days and induced by alloxan with doses of 90 mg/kgBW of rats, and treatment group (K2) was given a high-fat diet for 7 days, induced by alloxan and received the apple vinegar (Malus sylvestris Mill) of manalagi varieties with a dose of 0,27 ml/100 g BW of rats for 14 days. The results by using one way ANOVA showed the significance value of the data p = 0,974 (p>0,05) so that there is no significant difference of the mean of blood triglycerides levels between K0, K1 and K2. This study concluded that apple vinegar (Malus sylvestris Mill) of manalagi varieties can not significantly lower the blood triglyceride levels of white male rats (Rattus norvegicus) wistar strain with high-fat diet and induced by alloxan. Further study about apple vinegar of manalagi varieties is required to define its effects. Â Keywordsâ€”: High-Fat Diet, Alloxan, Triglyceride, Apple Vinegar (Malus sylvestris Mill) of Manalagi Varieties

Characteristics of The Patients with Low Back Pain in The Medical Rehabilitation Clinic, dr. Ramelan Naval Hospital Surabaya Lena Wijayaningrum; Herin Setianingsih; Agustin Silfi Rahayu
Denta Journal Kedokteran Gigi Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background : The total number of visit of patients with low back pain in the Medical Rehabilitation Subdepartment of Dr. Ramelan Naval Hospital Surabaya from January to November 2018 is approximately 38.7% of all visits. Low back pain is defined as pain between the edge of the ribs and the gluteus fold which can be.Material and Methods : This was a cross sectional study, based on the analysis of the medical records from the LBP patients in July to September 2018, in the Dr. Ramelan Hospital RSAL Medical Rehabilitation Clinic. The inclusion criteria of LBP is: patient with main symptom of pain or other unpleasant feelings in the lower spine and surrounding areas, between the edge of the ribs and the gluteus fold. Results : There were 151 data analyzed from July to September 2018, patients with pain complaints were (86.84%). The data obtained showed majority of patients was 51-60 years old. Most of the patients were women.Conclusion : Most of the patients diagnosed with Low Back Pain (LBP) at the Medical Rehabilitation Clinic of RSAL Dr. Ramelan Surabaya, was 51-60 years old, women were the majority, 80%s had complain of pain and there were any of comorbidities.

Pengaruh Pemberian Ekstrak Rumput Laut Merah (Kappaphycus alvarezii) terhadap Kadar LDL pada Tikus Putih (Rattus norvegicus) Jantan Galur Wistar yang Diberi Diet Tinggi Lemak MENTARI AMENDA SAPUTRI; HERIN SETIANINGSIH
HANG TUAH MEDICAL JOURNAL Vol 15 No 2 (2018): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Penyakit kardiovaskular merupakan penyebab kematian nomor satu di dunia. Gaya hidup masyarakat terutama dalam mengkonsumsi diet yang tidak sehat dapat meningkatkan kadar LDL yang dapat menyebabkan penyakit kardiovaskular. Rumput laut merah (Kappaphycus alvarezii) yang banyak dibudidayakan di Indonesia mengandung flavonoid dan triterpenoid yang diduga dapat menurunkan kadar LDL. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak rumput laut merah (Kappaphycus alvarezii) terhadap kadar LDL pada tikus putih (Rattus norvegicus) jantan galur Wistar yang diberi diet tinggi lemak. 113 Penelitian ini adalah penelitian eksperimental murni laboratorik dengan rancangan penelitian Post Test Control Group Design. Sampel yang digunakan adalah 24 ekor tikus putih (Rattus norvegicus) jantan galur Wistar yang dibagi ke dalam tiga kelompok: kelompok yang diberi diet standar selama 28 hari (K1), kelompok yang diberi diet tinggi lemak selama 28 hari (K2), dan kelompok yang diberi diet tinggi lemak selama 28 hari dan pada hari ke-15 sampai hari ke-28 diberi ekstrak rumput laut merah (Kappaphycus alvarezii) dengan dosis 140mg/200grBB/hari (K3). Hasil analisis statistik One Way Anova menunjukkan bahwa terdapat perbedaan kadar LDL yang signifikan antara ketiga kelompok pada penelitian ini (p<0,001). Kadar LDL pada K2 ( X =16,00±3,29) meningkat secara bermakna dibandingkan dengan K1 ( X =10,62±1,77). Sedangkan kadar LDL pada K3 ( X =6,88±2,42) menurun secara bermakna dibandingkan dengan K2. Dari hasil penelitian ini dapat disimpulkan bahwa ekstrak rumput laut merah (Kappaphycus alvarezii) berpengaruh terhadap kadar LDL darah pada tikus putih (Rattus norvegicus) jantan galur Wistar yang diberi diet tinggi lemak.

Hubungan Tingkat Pengetahuan dan Sikap Masyarakat dengan Upaya Pencegahan Covid-19 di Mataram STEFANNY ANGELINE BUDIARTO; HERIN SETIANINGSIH; WAHYU PRASASTI MUTIADESI
HANG TUAH MEDICAL JOURNAL Vol 19 No 1 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v19i1.66

Background : Coronavirus disease 19 is a disease caused by a corona virus which spreads through droplets. The rapid spread of the virus and the increasing incidence of covid-19 must be stopped immediately with specific prevention and handling. The community has a big role to play in preventing Covid-19. A good efforts of prevention really need the role of several factors such as knowledge and attitude. Objective : to analyze the relationship between knowledge and attitude of the community with the effort from preventing coronavirus disease 19 in Cakranegara Selatan village, Mataram City. Method : analytical observation with cross sectional design. The population in this study were people aged 18-40 years who lived in Cakranegara Selatan village. The sampels in this study were 397 people and the sampel was taken using purposive sampling. The instruments used in this study are modified online questionare and already passed validity and reliability test. Bivariate analysis uses the Correlation Spearman’s test with SPSS application. Result : univariate analysis showed 87,4% majority of respondent have good knowledge, 53,4% of respondent have enough attitude and 55,3% of respondent have bad effort of preventing the coronavirus disease 19. The bivariate analysis using Correlation Spearman’s test result found there were a relationship between knowledge and effort of preventing covid-19 with p value=0,000 and a relationship between society attitude and effort of preventing covid-19 with p value=0,000. Conclusion : there is a relationship between knowledge and attitude of the community with the effort from preventing coronavirus disease 19 in Cakranegara Selatan village, Mataram City.

Kejadian Pasien drop out dari Rencana Pelayanan Rehabilitasi Medik Rumkital di RSAL Dr. Ramelan LENA WIJAYANINGRUM; HERIN SETIANINGSIH; SETIYONO
HANG TUAH MEDICAL JOURNAL Vol 18 No 2 (2021): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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ABSTRACT Background : The high number of patient visits to medical rehabilitation clinic, from January to June 2018 is 13.772 patients, the number of patients from July to December 2018 is 11.142 patients, and the number of patients from januari to july 2019 is 13.781 patients.Therefore it is important to know the continuity of service, as planned by medical rehabilitation specialist. Methode : Descriptive research with population was obtained in medical record for duration 1 December 2019 to 29 February 2020 in the medical rehabilitation clinic of Dr Ramelan Surabaya Result : Patient visits that dropped out in 3 months were 795 patients (less than 10 visit in 3 months ). Patient visits that did not drop out in 3 months were 194 patients more than or equal to 10 visits in 3 months Conclusion : The incidence of patient drop out for planned rehabilitation services is 80,3842%. So the incidence of patient drop-out for planned rehabilitation services is not meeting the standards

Characteristics of The Patients with Low Back Pain in The Medical Rehabilitation Clinic, dr. Ramelan Naval Hospital Surabaya Lena Wijayaningrum; Herin Setianingsih; Agustin Silfi Rahayu
Oceana Biomedicina Journal Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v2i2.32

Background : The total number of visit of patients with low back pain in the Medical Rehabilitation Subdepartment of Dr. Ramelan Naval Hospital Surabaya from January to November 2018 is approximately 38.7% of all visits. Low back pain is defined as pain between the edge of the ribs and the gluteus fold which can be.Material and Methods : This was a cross sectional study, based on the analysis of the medical records from the LBP patients in July to September 2018, in the Dr. Ramelan Hospital RSAL Medical Rehabilitation Clinic. The inclusion criteria of LBP is: patient with main symptom of pain or other unpleasant feelings in the lower spine and surrounding areas, between the edge of the ribs and the gluteus fold. Results : There were 151 data analyzed from July to September 2018, patients with pain complaints were (86.84%). The data obtained showed majority of patients was 51-60 years old. Most of the patients were women.Conclusion : Most of the patients diagnosed with Low Back Pain (LBP) at the Medical Rehabilitation Clinic of RSAL Dr. Ramelan Surabaya, was 51-60 years old, women were the majority, 80%s had complain of pain and there were any of comorbidities.

Pengaruh Pemberian Oksigen Hiperbarik terhadap Kadar LDL Tikus Putih (Rattus norvegicus) Galur Sprague dawley yang kemudian Diberi Diet Tinggi Lemak Ika Apriyanti Arum Putri; Herin Setianingsih
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 8, No 1 (2019): EDISI MARET 2019 (available online since April 2019)
Publisher : Universitas Wijaya Kusuma Surabaya

Menurut WHO (2017), dari seluruh kematian akibat penyakit kardiovaskular 7,4 juta (42,3%) di antaranya disebabkan oleh Penyakit Jantung Koroner (PJK). Lipid, khususnya low density lipoprotein (LDL) merupakan salah satu faktor penting penyebab terjadinya PJK, mengingat perannya dalam proses aterogenesis. Terapi Oksigen Hiperbarik diketahui dapat menurunkan faktor resiko atherosklerosis seperti hiperkolesterolemia pada tekanan 1,5 ATA dan 3 ATA. Hiperkolesterolemia ini ditandai dengan peningkatan pada trigliserida (TG), LDL, dan penurunan HDL. Penelitian ini bertujuan untuk mengetahui pengaruh terapi oksigen hiperbarik terhadap kadar LDL tikus putih (Rattus norvegicus) galur Sprague dawley yang kemudian diberi diet tinggi lemak. Penelitian ini adalah penelitian eksperimental murni laboratoris. Subjek pada penelitian ini adalah 32 tikus putih (Rattus norvegicus) galur Sprague dawley yang dibagi menjadi dua kelompok yakni kelompok kontrol dan perlakuan. Kelompok kontrol diberikan diet tinggi lemak selama 49 hari dan kelompok perlakuan yang diterapi oksigen hiperbarik dengan kadar oksigen 98% tekanan 2,4 ATA selama 10 hari kemudian diberi diet tinggi lemak selama 49 hari. Hasil penelitian didapatkan rata-rata LDL kelompok kontrol sebesar 63,43 mg/dl dan kelompok perlakuan adalah 44,43 mg/dl. Kemudian, dilakukan uji hipotesa menggunakan metode Mann Whitney dan didapatkan nilai signifikansi (p) adalah 0,004 atau p<α sehingga dapat ditarik kesimpulan bahwa pada penelitian ini ada perbedaan kadar LDL darah tikus pada kedua kelompok perlakuan atau H1 diterima. Terapi oksigen hiperbarik berpengaruh terhadap penurunan kadar LDL darah pada tikus putih (Rattus norvegicus) galur Sprague dawley sebelum diberi diet tinggi lemak.

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