<![CDATA[Objective: To determine the expression of Phosphatase Regenerating
Liver-3 (PRL-3) and E-Cadherin in the epithelial ovarian cancer
on various stages and differentiation grades.
Method: This was a cross-sectional study design conducted at
Obstetrics and Gynecology Department of several teaching hospitals,
Faculty of Medicine Universitas Hasanuddin from January
to June 2015. The expression of PRL-3 and E-cadherin was
assessed immunohistochemically in 40 patients with epithelial
ovarian cancer including 15 patients in early stage and 25 patients
in advanced stage. We used the Fisher’s exact test with the
significance of p0.05). The significant difference was
found in the expression of E-cadherin whereas the high expression
was shown at early stage than advanced stage (p0.05). This study also pointed out no
correlation between the expression of PRL-3 and E-cadherin in
epithelial ovarian cancer (p>0.05).
Conclusion: PRL-3 overexpression does not decrease E-cadherin
expression in epithelial ovarian cancer.
Keywords: E-cadherin, epithelial ovarian cancer, PRL-3]]>
Copyrights © 2016
