Indonesian Journal of Pharmaceutical Science and Technology
Vol 5, No 3 (2018)

Essential Oil Composition, Antioxidant and Antibacterial Activities of Nutmeg (Myristica fragrans Houtt) from Garut West Java

Diki Prayugo Wibowo (Sekolah Tinggi Farmasi Indonesia, Bandung, 40266)
Yessi Febriana (Sekolah Tinggi Farmasi Indonesia, Bandung, 40266)
Hesti Riasari (Sekolah Tinggi Farmasi Indonesia, Bandung, 40266)
Diah Lia Auilifa (Sekolah Tinggi Farmasi Indonesia, Bandung, 40266)



Article Info

Publish Date
13 Oct 2018

Abstract

West Java is rich in essential oil-producing plants, essential oils known to be responsible for some pharmacological activities among its antioxidant and antimicrobial. This research aims to know antimicrobial, antioxidant activity and identify the components of a compound essential oil of nutmeg (Myristica fragrans Houtt.). Components chemistry identified with GC-MS (Gas Chromatography-Mass pectrometer). Antioxidant activity measured by using the DPPH method (2 2-diphenyl-1-picrylhydrazyl) at 516 λ wavelength absorbance. Antimicrobial activity determined Minimum Inhibitory Concentrations (MIC) and Minimum Bactericidal Concentrations (MBC) using microdilution method. The result of GC-MS showed the highest component on nutmeg containing 22.22% myristicin. The antioxidant test showed nutmeg had IC50 at 3,16%, essential oil showed antibacterial activity against Gram positive and Gram negative bacteria. Minimum inhibitory concentrations of essential oils range from 0.313% to 10%. The content of essential oils of nutmeg plants that grow in the area of West Java Garut can be used to overcome the problems of antioxidants and antimicrobial.Key words: Antioxidant, Antibacterial, Pala (Myristica fragrans Houtt), Chemical Composition.

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Journal Info

Abbrev

ijpst

Publisher

Subject

Computer Science & IT Medicine & Pharmacology

Description

Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan ...