VALENSI
Jurnal Kimia VALENSI Volume 4, No. 1, Mei 2018

Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Ace Tatang Hidayat (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Kindi Farabi (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Ida Nur Farida (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Kansy Haikal (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Nurlelasari Nurlelasari (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Desi Harneti Putri Huspa (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Rani Maharani (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Unang Supratman (Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran)
Yoshihito Shiono (Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan)

Article Info

Publish Date
31 May 2018

Abstract

Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065

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Journal Info
VALENSI
Website

Abbrev

valensi

Publisher

Universitas Islam Negeri Syarif Hidayatullah Jakarta

Subject

Chemistry

Description

Jurnal Kimia Valensi is a biannual and peer-reviewed open access journal published by Department of Chemistry, Faculty of Science and Technology UIN Syarif Hidayatullah Jakarta. This journal covering all aspect of ...