Jurnal Ilmu Dasar
Vol 15 No 2 (2014)

The Effect of Cinnamon (Cinnamomum burmanii) Aqueous Extract on Pancreas Structure of Diabetic Mice (Mus musculus) Strain Balb-C

Ika Dewi Kusumaningtyas (Biologi FMIPA, Universitas Jember)
Susantin Fajariyah (Biologi FMIPA, Universitas Jember)
Eva Tyas Utami (Biologi FMIPA, Universitas Jember)



Article Info

Publish Date
21 Feb 2015

Abstract

The objectives of this study were to observe effect and  the effective dose of cinnamon (Cinnamomum burmanii) aqueous extract on pancreas structure of strain Balb-C mice (Mus musculus) diabetic after alloxan exposure. A total of 30 strains Balb-C mice (Mus musculus L.) were divided into 5 groups. Negative control group was not induced  by alloxan and a positive control group was induced alloxan 0,15 mg/g bw intraperitoneally for 9 days. The treatment group was divided into 3 groups was induced alloxan 0,15 mg/g bw and given an aqueous  extract of cinnamon at a dose of 0,73 mg/g bw; 1,09 mg/g bw and 1,45 mg/g bw orally for 7 days. Mice were dissected pancreas histhological taken using paraffin method and Haematoxylin-eosin (HE) stain. The result showed giving aqueous extract of cinnamon gave a strong effect in the repairing of pancreas structure after giving the alloxsan and the most effective aqueouse xtract of cinnamon with dose of 0,73 mg/g bb was able to repair the structure of mice's pancreas after giving the alloxan. Keywords: Cinnamon,  pancreas structur,diabetic mice

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Journal Info

Abbrev

JID

Publisher

Subject

Control & Systems Engineering Mathematics

Description

Jurnal ILMU DASAR (JID) is a national peer-reviewed and open access journal that publishes research papers encompasses all aspects of natural sciences including Mathematics, Physics, Chemistry and Biology. JID publishes 2 issues in 1 volume per year. First published, volume 1 issue 1, in January ...