This study is applied research. It is focus in development material’s teaching course of calculus many variable basic on discovery learning model. In this research used developing 4D (define, design, develop, and disseminate). Destination research is for determine how to validity from development material’s teaching course of calculus many variable basic on discovery learning model, and how to effectiveness in development of teaching material courses of calculus many variable basic on discovery learning model. The result of the research is teaching material courses of calculus many variable on discovery learning model. The result of research material’s teaching course validated by experts. Result of validity is calculated with average for each indicator. Therefore effectiveness its calculate with means of student response to material’s teaching course. In this research result that material’s teaching course is valid. Therefore, student response result is 94.45%, it means the effectiveness of teaching material course is very good.
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