JSFK (Jurnal Sains Farmasi & Klinis)
Vol 7, No 1 (2020): J Sains Farm Klin 7(1), April 2020

Formulation of Eel (Monopterus albus) extract membranes for wound dressing using plasticizers

Febriyenti Febriyenti (Fakultas Farmasi, Universitas Andalas Padang)
Rahmi Nofita (Faculty of Pharmacy, Andalas University)
Khalidazia Khalidazia (Faculty of Pharmacy, Andalas University)



Article Info

Publish Date
23 May 2020

Abstract

The types of wound dressing will affect wound healing processes. The membrane is one of the potential wound dressing that can maintain the moisture of the wound surface. The eel extract as an active ingredient could be added to the membrane formula to accelerate wound healing. This study aimed to formulate eel (Monopterus albus) extract membranes for wound dressing using some plasticizers. Polyvinyl alcohol (PVA) 146,000 was used as the polymer, while glycerol, propylene glycol,and polyethylene glycol (PEG) 400 were used as the plasticizers. Methylparaben and propylparaben were added as preservatives. Evaluations included thickness, water vapor permeability, and mechanical properties of the membranes that consisted oftensile strength, elongation at break, and Young's modulus were performed. The result showed that the use of different types of plasticizers affected the mechanical properties of the eel extract membrane. The formula that used glycerol as the plasticizer produced membranes with the best water vapor permeability and mechanical properties.

Copyrights © 2020






Journal Info

Abbrev

jsfk

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Sains Farmasi & Klinis (J Sains Farm Klin) adalah jurnal ilmiah di bidang kefarmasian yang diterbitkan oleh Fakultas Farmasi Universitas Andalas bekerjasama dengan lembaga profesi "Ikatan Apoteker Indonesia" (IAI) daerah Sumatera Barat sejak tahun ...